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Protein

Uncharacterized protein YhfK

Gene

yhfK

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:G7721-MONOMER.
ECOL316407:JW5701-MONOMER.

Protein family/group databases

TCDBi2.A.85.1.3. the aromatic acid exporter (arae) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein YhfK
Gene namesi
Name:yhfK
Ordered Locus Names:b3358, JW5701
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12906. yhfK.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei24 – 44HelicalSequence analysisAdd BLAST21
Transmembranei67 – 87HelicalSequence analysisAdd BLAST21
Transmembranei89 – 109HelicalSequence analysisAdd BLAST21
Transmembranei115 – 135HelicalSequence analysisAdd BLAST21
Transmembranei139 – 159HelicalSequence analysisAdd BLAST21
Transmembranei383 – 403HelicalSequence analysisAdd BLAST21
Transmembranei420 – 440HelicalSequence analysisAdd BLAST21
Transmembranei461 – 481HelicalSequence analysisAdd BLAST21
Transmembranei491 – 511HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001695231 – 700Uncharacterized protein YhfKAdd BLAST700

Proteomic databases

PaxDbiP45537.
PRIDEiP45537.

Interactioni

Protein-protein interaction databases

BioGridi4262927. 168 interactors.
STRINGi511145.b3358.

Structurei

3D structure databases

ProteinModelPortaliP45537.
SMRiP45537.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the YccS/YhfK family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410613R. Bacteria.
COG1289. LUCA.
HOGENOMiHOG000125430.
InParanoidiP45537.
OMAiERAMDTA.
PhylomeDBiP45537.

Family and domain databases

InterProiIPR010020. Integral_membrane_YCCS_YHJK.
IPR032692. YccS_N.
[Graphical view]
PfamiPF12805. FUSC-like. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01667. YCCS_YHJK. 1 hit.

Sequencei

Sequence statusi: Complete.

P45537-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFPPMWRRLI YHPDINYALR QTLVLCLPVA VGLMLGELRF GLLFSLVPAC
60 70 80 90 100
CNIAGLDTPH KRFFKRLIIG ASLFATCSLL TQLLLAKDVP LPFLLTGLTL
110 120 130 140 150
VLGVTAELGP LHAKLLPASL LAAIFTLSLA GYMPVWEPLL IYALGTLWYG
160 170 180 190 200
LFNWFWFWIW REQPLRESLS LLYRELADYC EAKYSLLTQH TDPEKALPPL
210 220 230 240 250
LVRQQKAVDL ITQCYQQMHM LSAQNNTDYK RMLRIFQEAL DLQEHISVSL
260 270 280 290 300
HQPEEVQKLV ERSHAEEVIR WNAQTVAARL RVLADDILYH RLPTRFTMEK
310 320 330 340 350
QIGALEKIAR QHPDNPVGQF CYWHFSRIAR VLRTQKPLYA RDLLADKQRR
360 370 380 390 400
MPLLPALKSY LSLKSPALRN AGRLSVMLSV ASLMGTALHL PKSYWILMTV
410 420 430 440 450
LLVTQNGYGA TRLRIVNRSV GTVVGLIIAG VALHFKIPEG YTLTLMLITT
460 470 480 490 500
LASYLILRKN YGWATVGFTI TAVYTLQLLW LNGEQYILPR LIDTIIGCLI
510 520 530 540 550
AFGGTVWLWP QWQSGLLRKN AHDALEAYQE AIRLILSEDP QPTPLAWQRM
560 570 580 590 600
RVNQAHNTLY NSLNQAMQEP AFNSHYLADM KLWVTHSQFI VEHINAMTTL
610 620 630 640 650
AREHRALPPE LAQEYLQSCE IAIQRCQQRL EYDEPGSSGD ANIMDAPEMQ
660 670 680 690 700
PHEGAAGTLE QHLQRVIGHL NTMHTISSMA WRQRPHHGIW LSRKLRDSKA
Length:700
Mass (Da):79,972
Last modified:July 11, 2001 - v2
Checksum:i4E3532A1129AB6A7
GO

Sequence cautioni

The sequence AAA58155 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58155.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76383.2.
AP009048 Genomic DNA. Translation: BAE77932.1.
RefSeqiNP_417817.2. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAC76383; AAC76383; b3358.
BAE77932; BAE77932; BAE77932.
GeneIDi947866.
KEGGiecj:JW5701.
eco:b3358.
PATRICi32122150. VBIEscCol129921_3452.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58155.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76383.2.
AP009048 Genomic DNA. Translation: BAE77932.1.
RefSeqiNP_417817.2. NC_000913.3.

3D structure databases

ProteinModelPortaliP45537.
SMRiP45537.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262927. 168 interactors.
STRINGi511145.b3358.

Protein family/group databases

TCDBi2.A.85.1.3. the aromatic acid exporter (arae) family.

Proteomic databases

PaxDbiP45537.
PRIDEiP45537.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76383; AAC76383; b3358.
BAE77932; BAE77932; BAE77932.
GeneIDi947866.
KEGGiecj:JW5701.
eco:b3358.
PATRICi32122150. VBIEscCol129921_3452.

Organism-specific databases

EchoBASEiEB2743.
EcoGeneiEG12906. yhfK.

Phylogenomic databases

eggNOGiENOG410613R. Bacteria.
COG1289. LUCA.
HOGENOMiHOG000125430.
InParanoidiP45537.
OMAiERAMDTA.
PhylomeDBiP45537.

Enzyme and pathway databases

BioCyciEcoCyc:G7721-MONOMER.
ECOL316407:JW5701-MONOMER.

Miscellaneous databases

PROiP45537.

Family and domain databases

InterProiIPR010020. Integral_membrane_YCCS_YHJK.
IPR032692. YccS_N.
[Graphical view]
PfamiPF12805. FUSC-like. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01667. YCCS_YHJK. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYHFK_ECOLI
AccessioniPrimary (citable) accession number: P45537
Secondary accession number(s): Q2M724
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: July 11, 2001
Last modified: November 2, 2016
This is version 113 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.