Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uncharacterized protease YhbU

Gene

yhbU

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease

Enzyme and pathway databases

BioCyciEcoCyc:G7652-MONOMER.
ECOL316407:JW3127-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protease YhbU (EC:3.4.-.-)
Gene namesi
Name:yhbU
Ordered Locus Names:b3158, JW3127
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12790. yhbU.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1515Sequence analysisAdd
BLAST
Chaini16 – 331316Uncharacterized protease YhbUPRO_0000028525Add
BLAST

Proteomic databases

PaxDbiP45527.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
groLP0A6F53EBI-561157,EBI-543750

Protein-protein interaction databases

BioGridi4259275. 73 interactions.
DIPiDIP-12268N.
IntActiP45527. 11 interactions.
MINTiMINT-1243533.
STRINGi511145.b3158.

Structurei

3D structure databases

ProteinModelPortaliP45527.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase U32 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105CFP. Bacteria.
COG0826. LUCA.
HOGENOMiHOG000276098.
InParanoidiP45527.
KOiK08303.
OMAiNTIIYDH.
OrthoDBiEOG661H5R.
PhylomeDBiP45527.

Family and domain databases

InterProiIPR001539. Peptidase_U32.
IPR022998. ThiaminP_synth_SF.
[Graphical view]
PfamiPF01136. Peptidase_U32. 1 hit.
[Graphical view]
SUPFAMiSSF51391. SSF51391. 1 hit.
PROSITEiPS01276. PEPTIDASE_U32. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P45527-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELLCPAGNL PALKAAIENG ADAVYIGLKD DTNARHFAGL NFTEKKLQEA
60 70 80 90 100
VSFVHQHRRK LHIAINTFAH PDGYARWQRA VDMAAQLGAD ALILADLAML
110 120 130 140 150
EYAAERYPHI ERHVSVQASA TNEEAINFYH RHFDVARVVL PRVLSIHQVK
160 170 180 190 200
QLARVTPVPL EVFAFGSLCI MSEGRCYLSS YLTGESPNTI GACSPARFVR
210 220 230 240 250
WQQTPQGLES RLNEVLIDRY QDGENAGYPT LCKGRYLVDG ERYHALEEPT
260 270 280 290 300
SLNTLELLPE LMAANIASVK IEGRQRSPAY VSQVAKVWRQ AIDRCKADPQ
310 320 330
NFVPQSAWME TLGSMSEGTQ TTLGAYHRKW Q
Length:331
Mass (Da):37,047
Last modified:November 1, 1995 - v1
Checksum:i2AFDED5929C4CFA7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA57961.1.
U00096 Genomic DNA. Translation: AAC76192.1.
AP009048 Genomic DNA. Translation: BAE77204.1.
PIRiB65106.
RefSeqiNP_417627.1. NC_000913.3.
WP_001311152.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76192; AAC76192; b3158.
BAE77204; BAE77204; BAE77204.
GeneIDi949115.
KEGGiecj:JW3127.
eco:b3158.
PATRICi32121734. VBIEscCol129921_3253.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA57961.1.
U00096 Genomic DNA. Translation: AAC76192.1.
AP009048 Genomic DNA. Translation: BAE77204.1.
PIRiB65106.
RefSeqiNP_417627.1. NC_000913.3.
WP_001311152.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP45527.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259275. 73 interactions.
DIPiDIP-12268N.
IntActiP45527. 11 interactions.
MINTiMINT-1243533.
STRINGi511145.b3158.

Proteomic databases

PaxDbiP45527.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76192; AAC76192; b3158.
BAE77204; BAE77204; BAE77204.
GeneIDi949115.
KEGGiecj:JW3127.
eco:b3158.
PATRICi32121734. VBIEscCol129921_3253.

Organism-specific databases

EchoBASEiEB2642.
EcoGeneiEG12790. yhbU.

Phylogenomic databases

eggNOGiENOG4105CFP. Bacteria.
COG0826. LUCA.
HOGENOMiHOG000276098.
InParanoidiP45527.
KOiK08303.
OMAiNTIIYDH.
OrthoDBiEOG661H5R.
PhylomeDBiP45527.

Enzyme and pathway databases

BioCyciEcoCyc:G7652-MONOMER.
ECOL316407:JW3127-MONOMER.

Miscellaneous databases

PROiP45527.

Family and domain databases

InterProiIPR001539. Peptidase_U32.
IPR022998. ThiaminP_synth_SF.
[Graphical view]
PfamiPF01136. Peptidase_U32. 1 hit.
[Graphical view]
SUPFAMiSSF51391. SSF51391. 1 hit.
PROSITEiPS01276. PEPTIDASE_U32. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYHBU_ECOLI
AccessioniPrimary (citable) accession number: P45527
Secondary accession number(s): Q2M952
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: April 13, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.