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P45515

- PDUO_CITFR

UniProt

P45515 - PDUO_CITFR

Protein

Cob(I)yrinic acid a,c-diamide adenosyltransferase

Gene
N/A
Organism
Citrobacter freundii
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + cob(I)yrinic acid a,c-diamide = triphosphate + adenosylcob(III)yrinic acid a,c-diamide.
    ATP + cobinamide = triphosphate + adenosylcobinamide.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei24 – 241ATPBy similarity
    Binding sitei155 – 1551ATPBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi6 – 149ATPBy similarity
    Nucleotide bindingi131 – 1366ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. cob(I)yrinic acid a,c-diamide adenosyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cobalamin biosynthetic process Source: UniProtKB-UniPathway
    2. porphyrin-containing compound biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Cobalamin biosynthesis, Porphyrin biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    UniPathwayiUPA00148; UER00233.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cob(I)yrinic acid a,c-diamide adenosyltransferase (EC:2.5.1.17)
    Alternative name(s):
    Cob(I)alamin adenosyltransferase
    ORFW
    OrganismiCitrobacter freundii
    Taxonomic identifieri546 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeCitrobacterCitrobacter freundii complex

    Subcellular locationi

    Cytoplasm Curated

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 176176Cob(I)yrinic acid a,c-diamide adenosyltransferasePRO_0000103801Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP45515.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    Gene3Di1.20.1200.10. 1 hit.
    InterProiIPR016030. AdoCbl_synth_CblAdoTrfase-like.
    IPR029499. PduO-typ.
    [Graphical view]
    PfamiPF01923. Cob_adeno_trans. 1 hit.
    [Graphical view]
    ProDomiPD007457. AdoCbl_syn_CblAdoTrfase_PduO_N. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF89028. SSF89028. 1 hit.
    TIGRFAMsiTIGR00636. PduO_Nterm. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P45515-1 [UniParc]FASTAAdd to Basket

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    MYRIYTRTGD NGTTALFGGS RIDKDDIRVE AYGTVDELIS QLGVCYASTR    50
    QAELRQELHA MQKMLFVLGA ELASDQKGLT RLKQRIGEED IQALEQLIDR 100
    NMAQSGPLKE FVIPGKNLAS AQLHVARTLT RRLERILIAM GRTLTLRDEA 150
    RRYINRLSDA LFSMARIEET TPDVCA 176
    Length:176
    Mass (Da):19,846
    Last modified:November 1, 1995 - v1
    Checksum:iAEB560DD05EF3EB5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U09771 Genomic DNA. Translation: AAB48846.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U09771 Genomic DNA. Translation: AAB48846.1 .

    3D structure databases

    ProteinModelPortali P45515.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00148 ; UER00233 .

    Family and domain databases

    Gene3Di 1.20.1200.10. 1 hit.
    InterProi IPR016030. AdoCbl_synth_CblAdoTrfase-like.
    IPR029499. PduO-typ.
    [Graphical view ]
    Pfami PF01923. Cob_adeno_trans. 1 hit.
    [Graphical view ]
    ProDomi PD007457. AdoCbl_syn_CblAdoTrfase_PduO_N. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF89028. SSF89028. 1 hit.
    TIGRFAMsi TIGR00636. PduO_Nterm. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Daniel R., Gottschalk G.
      Submitted (MAY-1994) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 6750 / DSM 30040 / NCIB 8173 / M8BK.

    Entry informationi

    Entry nameiPDUO_CITFR
    AccessioniPrimary (citable) accession number: P45515
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3