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P45509

- CFA_CITFR

UniProt

P45509 - CFA_CITFR

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Protein

Cyclopropane-fatty-acyl-phospholipid synthase

Gene

cfa

Organism
Citrobacter freundii
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge.By similarity

Catalytic activityi

S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei61 – 611By similarity

GO - Molecular functioni

  1. cyclopropane-fatty-acyl-phospholipid synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. lipid biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism

Keywords - Ligandi

S-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclopropane-fatty-acyl-phospholipid synthase (EC:2.1.1.79)
Short name:
CFA synthase
Short name:
Cyclopropane fatty acid synthase
Gene namesi
Name:cfa
OrganismiCitrobacter freundii
Taxonomic identifieri546 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeCitrobacterCitrobacter freundii complex

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – 89›89Cyclopropane-fatty-acyl-phospholipid synthasePRO_0000089570Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP45509.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CFA/CMAS family.Curated

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
InterProiIPR003333. Mycolic_cyclopropane_synthase.
IPR029063. SAM-dependent_MTases-like.
[Graphical view]
PfamiPF02353. CMAS. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Fragment.

P45509-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
ISHIAEASES RFVMEDWHNF GSDYDKTLMA WHERFNQAWP ELSSRYSATF
60 70 80
RRMFNYYLCA CAGAFRARDI ELWQVLFSRG VEGGIRVYR
Length:89
Mass (Da):10,609
Last modified:November 1, 1995 - v1
Checksum:i7D0DDB9F377F72EA
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U09771 Genomic DNA. Translation: AAB48842.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U09771 Genomic DNA. Translation: AAB48842.1 .

3D structure databases

ProteinModelPortali P45509.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
InterProi IPR003333. Mycolic_cyclopropane_synthase.
IPR029063. SAM-dependent_MTases-like.
[Graphical view ]
Pfami PF02353. CMAS. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Daniel R., Gottschalk G.
    Submitted (MAY-1994) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 6750 / DSM 30040 / NCIB 8173 / M8BK.

Entry informationi

Entry nameiCFA_CITFR
AccessioniPrimary (citable) accession number: P45509
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: October 29, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3