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Protein

HTH-type transcriptional activator TtdR

Gene

ttdR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB-ygjE operon.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi23 – 42H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:EG12694-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional activator TtdR
Gene namesi
Name:ttdR
Synonyms:ygiP
Ordered Locus Names:b3060, JW3032
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12694. ttdR.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001057951 – 310HTH-type transcriptional activator TtdRAdd BLAST310

Proteomic databases

PaxDbiP45463.
PRIDEiP45463.

Interactioni

Protein-protein interaction databases

BioGridi4263515. 3 interactors.
DIPiDIP-12223N.
IntActiP45463. 6 interactors.
STRINGi316385.ECDH10B_3235.

Structurei

3D structure databases

ProteinModelPortaliP45463.
SMRiP45463.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 63HTH lysR-typePROSITE-ProRule annotationAdd BLAST58

Phylogenomic databases

eggNOGiENOG4105EJC. Bacteria.
ENOG410XNQA. LUCA.
HOGENOMiHOG000233519.
InParanoidiP45463.
KOiK21742.
PhylomeDBiP45463.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiView protein in PROSITE
PS50931. HTH_LYSR. 1 hit.

Sequencei

Sequence statusi: Complete.

P45463-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLNSWPLAKD LQVLVEIVHS GSFSAAAATL GQTPAFVTKR IQILENTLAT
60 70 80 90 100
TLLNRSARGV ALTESGQRCY EHALEILTQY QRLVDDVTQI KTRPEGMIRI
110 120 130 140 150
GCSFGFGRSH IAPAITELMR NYPELQVHFE LFDRQIDLVQ DNIDLDIRIN
160 170 180 190 200
DEIPDYYIAH LLTKNKRILC AAPEYLQKYP QPQSLQELSR HDCLVTKERD
210 220 230 240 250
MTHGIWELGN GQEKKSVKVS GHLSSNSGEI VLQWALEGKG IMLRSEWDVL
260 270 280 290 300
PFLESGKLVQ VLPEYAQSAN IWAVYREPLY RSMKLRVCVE FLAAWCQQRL
310
GKPDEGYQVM
Length:310
Mass (Da):35,315
Last modified:October 1, 1996 - v2
Checksum:i17C0072B72B08885
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28379 Genomic DNA. Translation: AAA89140.1.
U00096 Genomic DNA. Translation: AAC76096.1.
AP009048 Genomic DNA. Translation: BAE77111.1.
L14781 Unassigned DNA. No translation available.
PIRiB65094.
RefSeqiNP_417532.1. NC_000913.3.
WP_000935206.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76096; AAC76096; b3060.
BAE77111; BAE77111; BAE77111.
GeneIDi947562.
KEGGiecj:JW3032.
eco:b3060.
PATRICifig|1411691.4.peg.3671.

Similar proteinsi

Entry informationi

Entry nameiTTDR_ECOLI
AccessioniPrimary (citable) accession number: P45463
Secondary accession number(s): Q2M9E5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: October 1, 1996
Last modified: September 27, 2017
This is version 126 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene