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Protein

Malate synthase, glyoxysomal

Gene
N/A
Organism
Glycine max (Soybean) (Glycine hispida)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei179 – 1791Proton acceptorBy similarity
Active sitei465 – 4651Proton donorBy similarity

GO - Molecular functioni

  1. malate synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-UniPathway
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Glyoxylate bypass, Tricarboxylic acid cycle

Enzyme and pathway databases

UniPathwayiUPA00703; UER00720.

Names & Taxonomyi

Protein namesi
Recommended name:
Malate synthase, glyoxysomal (EC:2.3.3.9)
Short name:
MS
OrganismiGlycine max (Soybean) (Glycine hispida)
Taxonomic identifieri3847 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja
ProteomesiUP000008827 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

  1. glyoxysome Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Glyoxysome, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – 564›564Malate synthase, glyoxysomalPRO_0000166873Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP45458.

Structurei

3D structure databases

ProteinModelPortaliP45458.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi562 – 5643Microbody targeting signalSequence Analysis

Sequence similaritiesi

Belongs to the malate synthase family.Curated

Family and domain databases

InterProiIPR011076. Malate_synth-like.
IPR006252. Malate_synthA.
IPR001465. Malate_synthase.
IPR019830. Malate_synthase_CS.
[Graphical view]
PfamiPF01274. Malate_synthase. 1 hit.
[Graphical view]
PIRSFiPIRSF001363. Malate_synth. 1 hit.
SUPFAMiSSF51645. SSF51645. 1 hit.
TIGRFAMsiTIGR01344. malate_syn_A. 1 hit.
PROSITEiPS00510. MALATE_SYNTHASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

P45458-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GTYGYPTPAV KKIESYYDVP EGVDIRGRYD AEFAKILTKD ALKFVADLQR
60 70 80 90 100
EFRNHIKYAL ECRREAKKKY NEGALPEFDP ATTYIREQEW VCAPVPPAVA
110 120 130 140 150
DRKVEITGPV DRKMVINALN SGAKVFMADF EDALSPGWEN LMRGQVNLKD
160 170 180 190 200
AVAGTISLHD KARNRVYKLN DQTAKLFVRP RGWHLPEAHI LIDGEPATGC
210 220 230 240 250
LVDFGLYFYH SYSAFRRTQG AGFGPFFYLP KMEHSREAKI WNNVFEKAEK
260 270 280 290 300
VAGIERGSIR ATVLIETLPA VFQMNEILYE LKDHSVGLNC GRWDYIFSYV
310 320 330 340 350
KTFQAHPDRL LPDRVLVGMT QHFMKSYSDL LIRTCHRRGV HAMGGMAAQI
360 370 380 390 400
PIKEDPVANE VALELVRKDK LREVKAGHDG TWAAHPGLIP ACMEIFNNNM
410 420 430 440 450
GNASNQIDTV KREDGANITE QDLLQIPRGA RTMEGLRLNT RVGIQYVAAW
460 470 480 490 500
LTGSGSVPLY NLMEDAATAE ISRVQNWQWL KYGVELNGDG LGVKVNKELF
510 520 530 540 550
GRVVEEEMAR IEKEVGTEKF KEGMYKEACK IFTRQCTSPM LDDFLTLDAY
560
NYIVVHHPRE TSKL
Length:564
Mass (Da):63,909
Last modified:October 31, 1995 - v1
Checksum:iEE175238AEA6185A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L01629 mRNA. Translation: AAC37465.1.
PIRiT07690.
UniGeneiGma.31590.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L01629 mRNA. Translation: AAC37465.1.
PIRiT07690.
UniGeneiGma.31590.

3D structure databases

ProteinModelPortaliP45458.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayiUPA00703; UER00720.

Gene expression databases

GenevestigatoriP45458.

Family and domain databases

InterProiIPR011076. Malate_synth-like.
IPR006252. Malate_synthA.
IPR001465. Malate_synthase.
IPR019830. Malate_synthase_CS.
[Graphical view]
PfamiPF01274. Malate_synthase. 1 hit.
[Graphical view]
PIRSFiPIRSF001363. Malate_synth. 1 hit.
SUPFAMiSSF51645. SSF51645. 1 hit.
TIGRFAMsiTIGR01344. malate_syn_A. 1 hit.
PROSITEiPS00510. MALATE_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Glyoxysomal malate dehydrogenase and malate synthase from soybean cotyledons (Glycine max L.): enzyme association, antibody production and cDNA cloning."
    Guex N., Henry H., Flach J., Richter H., Widmer F.
    Planta 197:369-375(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Maple Arrow.
    Tissue: Cotyledon.

Entry informationi

Entry nameiMASY_SOYBN
AccessioniPrimary (citable) accession number: P45458
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 1995
Last sequence update: October 31, 1995
Last modified: January 6, 2015
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.