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P45456

- ACEA1_SOYBN

UniProt

P45456 - ACEA1_SOYBN

Protein

Isocitrate lyase 1

Gene

ICL1

Organism
Glycine max (Soybean) (Glycine hispida)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    • Comment

    Functioni

    Involved in storage lipid mobilization during the growth of higher plant seedling.By similarity

    Catalytic activityi

    Isocitrate = succinate + glyoxylate.PROSITE-ProRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei195 – 1951PROSITE-ProRule annotation

    GO - Molecular functioni

    1. isocitrate lyase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glyoxylate cycle Source: UniProtKB-UniPathway
    2. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Glyoxylate bypass, Tricarboxylic acid cycle

    Enzyme and pathway databases

    UniPathwayiUPA00703; UER00719.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Isocitrate lyase 1 (EC:4.1.3.1)
    Short name:
    ICL 1
    Short name:
    Isocitrase 1
    Short name:
    Isocitratase 1
    Gene namesi
    Name:ICL1
    OrganismiGlycine max (Soybean) (Glycine hispida)
    Taxonomic identifieri3847 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja
    ProteomesiUP000008827: Unplaced

    Subcellular locationi

    GO - Cellular componenti

    1. glyoxysome Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Glyoxysome, Peroxisome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – 558›558Isocitrate lyase 1PRO_0000068811Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriP45456.

    Interactioni

    Subunit structurei

    Homotetramer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliP45456.
    SMRiP45456. Positions 1-518.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi556 – 5583Microbody targeting signalSequence Analysis

    Sequence similaritiesi

    Family and domain databases

    Gene3Di3.20.20.60. 2 hits.
    InterProiIPR006254. Isocitrate_lyase.
    IPR018523. Isocitrate_lyase_ph_CS.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PANTHERiPTHR21631:SF3. PTHR21631:SF3. 1 hit.
    PfamiPF00463. ICL. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001362. Isocit_lyase. 1 hit.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    TIGRFAMsiTIGR01346. isocit_lyase. 1 hit.
    PROSITEiPS00161. ISOCITRATE_LYASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    P45456-1 [UniParc]FASTAAdd to Basket

    « Hide

    EAEVAEVQAW WNSERFRLTK RPYTARDVVS LRGNLRQTYA SNEMAKKLWR    50
    LLKNHQANGT ASRTFGALDP VQVTQMAKHL DTIYVSGWQC SATHTTSNEP 100
    GPDLADYPYD TVPNKVEHLF FAQQYHDRKQ KEERMRMSRE ERARTPYVDY 150
    LRPIIADGDT GFGGTTATVK LCKLFVERGA AGIHIEDQSS VTKKCGHMAG 200
    KVLVAISEHI NRLVAARLQF DVMGVETVLV ARTDAEAANL IQSNIDTRDH 250
    QFILGVTNPN LKGKSLATLM QQGMAAGKNG AELQALEDEW LSKAQLKTLS 300
    EAVVEAIERQ NNIGEEEKRR KLNEWMHHSS YERCLSNEEG REIAEKLGVR 350
    NLFWDWDLPR TREGFYRFKG SVTASVVRGC AFSPHADVIW METASPNVVE 400
    CTEFSEGVRS KHPQMMLGYN LSPSFNWDAS GMSDEQMKDF IPKIAKLGYV 450
    WQFITVGGLH SNALITSTFA RDFANRGMLA YVERIQREER NNGVDTLAHQ 500
    KWAGANYYDR YLKTVQGGVA STAAMGKGVT EEQFKESWTR SGAVNIDRGS 550
    IVVAKARM 558
    Length:558
    Mass (Da):62,845
    Last modified:November 1, 1995 - v1
    Checksum:i99B5CA5EA24F5DDB
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L02329 mRNA. Translation: AAA33976.1.
    PIRiT07631.
    UniGeneiGma.28715.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L02329 mRNA. Translation: AAA33976.1 .
    PIRi T07631.
    UniGenei Gma.28715.

    3D structure databases

    ProteinModelPortali P45456.
    SMRi P45456. Positions 1-518.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00703 ; UER00719 .

    Gene expression databases

    Genevestigatori P45456.

    Family and domain databases

    Gene3Di 3.20.20.60. 2 hits.
    InterProi IPR006254. Isocitrate_lyase.
    IPR018523. Isocitrate_lyase_ph_CS.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    PANTHERi PTHR21631:SF3. PTHR21631:SF3. 1 hit.
    Pfami PF00463. ICL. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001362. Isocit_lyase. 1 hit.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    TIGRFAMsi TIGR01346. isocit_lyase. 1 hit.
    PROSITEi PS00161. ISOCITRATE_LYASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Guex N., Henry H., Widmer F.
      Submitted (AUG-1993) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. Maple Arrow.
      Tissue: Cotyledon.

    Entry informationi

    Entry nameiACEA1_SOYBN
    AccessioniPrimary (citable) accession number: P45456
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3