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Protein

Uncharacterized outer membrane usher protein YhcD

Gene

yhcD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in the export and assembly of a fimbrial subunit across the outer membrane.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Fimbrium biogenesis, Transport

Enzyme and pathway databases

BioCyciEcoCyc:G7670-MONOMER.
ECOL316407:JW3183-MONOMER.

Protein family/group databases

TCDBi1.B.11.5.1. the outer membrane fimbrial usher porin (fup) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized outer membrane usher protein YhcD
Gene namesi
Name:yhcD
Ordered Locus Names:b3216, JW3183
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12810. yhcD.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121Sequence analysisAdd
BLAST
Chaini22 – 793772Uncharacterized outer membrane usher protein YhcDPRO_0000009333Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi769 ↔ 792Sequence analysis

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiP45420.
PRIDEiP45420.

Interactioni

Protein-protein interaction databases

BioGridi4261874. 172 interactions.
DIPiDIP-12277N.
STRINGi511145.b3216.

Structurei

3D structure databases

ProteinModelPortaliP45420.
SMRiP45420. Positions 149-793.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the fimbrial export usher family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane beta strand

Phylogenomic databases

eggNOGiENOG4105E6S. Bacteria.
ENOG410XPN5. LUCA.
HOGENOMiHOG000260663.
OMAiNASINWA.
OrthoDBiEOG61ZTB2.
PhylomeDBiP45420.

Family and domain databases

InterProiIPR000015. Fimb_usher.
IPR018030. Fimbrial_membr_usher_CS.
IPR025949. PapC-like_C.
IPR025885. PapC_N.
[Graphical view]
PANTHERiPTHR30451. PTHR30451. 1 hit.
PfamiPF13953. PapC_C. 1 hit.
PF13954. PapC_N. 1 hit.
PF00577. Usher. 1 hit.
[Graphical view]
PROSITEiPS01151. FIMBRIAL_USHER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P45420-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKKTLLAYT IGFAFSPPAN ADGIEIAAVD FDRETLKSLG VDPNISHYFS
60 70 80 90 100
RSARFLPGEY SLIVSVNGEK KGNIATRFDE NGDICLDQAF LQQAGLKIPS
110 120 130 140 150
EEKNGCYDYI LSYPGTTITP LPNQEALDII VSPQAIIPIG LDLTNAATGG
160 170 180 190 200
TAALLNYSLM SSRAEFSNGS SDYSQAALEG GININDWMLR SHQFLTQTNG
210 220 230 240 250
TFSNQNSSTY LQRTFTDLKT LMRAGEVNLN NSVLEGASIY GIEIAPDNAL
260 270 280 290 300
QTSGSGVQVT GIANTSQARV EIRQQGVLIH SILVPAGAFT IPDVPVRNGN
310 320 330 340 350
SDLNVTVVET DGSSHNYIVP STLFNQHVES FQGYRFAIGR VDDDYDESPW
360 370 380 390 400
VISASSGWNL TRWSAMNGGV IVAENYQAAS IRSSLVPLPD LTVSSQISTS
410 420 430 440 450
QDTKDSLQGQ KYRLDANYNL PFSLGLTTSL TRSDRHYREL SEAIDDDYTD
460 470 480 490 500
PTKSTYALGL NWSNSILGGF NISGYKTYSY DGDNDSSNLN INWNKAFKHA
510 520 530 540 550
TVSVNWQHQL SASENNEDDG DLFYVNISIP FGRSNTATLY TRHDDHKTHY
560 570 580 590 600
GTGVMGVVSD EMSYYVNAER DHDERETSLN GSISSNLHYT QVSLAAGASG
610 620 630 640 650
SDSRTYNGTM SGGIAVHDQG VTFSPWTIND TFAIAKMDNN IAGVRITSQA
660 670 680 690 700
GPVWTDFRGN AVIPSIQPWR TSGVEIDTAS LPKNVDIGNG TKMIKQGRGA
710 720 730 740 750
VGKVGFSAIT QRRALLNITL SDGKKLPRGV AIEDSEGNYL TTSVDDGVVF
760 770 780 790
LNNIKPDMVL DIKDEQQSCR IHLTFPEDAP KDVFYETATG ECQ
Length:793
Mass (Da):86,289
Last modified:November 1, 1995 - v1
Checksum:i952CFAB835BB3681
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58018.1.
U00096 Genomic DNA. Translation: AAC76248.1.
AP009048 Genomic DNA. Translation: BAE77260.1.
PIRiB65113.
RefSeqiNP_417683.1. NC_000913.3.
WP_000914994.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76248; AAC76248; b3216.
BAE77260; BAE77260; BAE77260.
GeneIDi947738.
KEGGiecj:JW3183.
eco:b3216.
PATRICi32121854. VBIEscCol129921_3311.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58018.1.
U00096 Genomic DNA. Translation: AAC76248.1.
AP009048 Genomic DNA. Translation: BAE77260.1.
PIRiB65113.
RefSeqiNP_417683.1. NC_000913.3.
WP_000914994.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP45420.
SMRiP45420. Positions 149-793.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261874. 172 interactions.
DIPiDIP-12277N.
STRINGi511145.b3216.

Protein family/group databases

TCDBi1.B.11.5.1. the outer membrane fimbrial usher porin (fup) family.

Proteomic databases

PaxDbiP45420.
PRIDEiP45420.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76248; AAC76248; b3216.
BAE77260; BAE77260; BAE77260.
GeneIDi947738.
KEGGiecj:JW3183.
eco:b3216.
PATRICi32121854. VBIEscCol129921_3311.

Organism-specific databases

EchoBASEiEB2661.
EcoGeneiEG12810. yhcD.

Phylogenomic databases

eggNOGiENOG4105E6S. Bacteria.
ENOG410XPN5. LUCA.
HOGENOMiHOG000260663.
OMAiNASINWA.
OrthoDBiEOG61ZTB2.
PhylomeDBiP45420.

Enzyme and pathway databases

BioCyciEcoCyc:G7670-MONOMER.
ECOL316407:JW3183-MONOMER.

Miscellaneous databases

PROiP45420.

Family and domain databases

InterProiIPR000015. Fimb_usher.
IPR018030. Fimbrial_membr_usher_CS.
IPR025949. PapC-like_C.
IPR025885. PapC_N.
[Graphical view]
PANTHERiPTHR30451. PTHR30451. 1 hit.
PfamiPF13953. PapC_C. 1 hit.
PF13954. PapC_N. 1 hit.
PF00577. Usher. 1 hit.
[Graphical view]
PROSITEiPS01151. FIMBRIAL_USHER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYHCD_ECOLI
AccessioniPrimary (citable) accession number: P45420
Secondary accession number(s): Q2M8Z6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: January 20, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.