Reviewed, UniProtKB/Swiss-Prot P45416 (KDGK_DICD3)

Names and origin

Protein names

Recommended name:
    2-dehydro-3-deoxygluconokinase
    EC=2.7.1.45
Alternative name(s):
    2-keto-3-deoxygluconokinase
    3-deoxy-2-oxo-D-gluconate kinase
    KDG kinase

Gene names

Name:

kdgK

Organism

Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))

Taxonomic identifier

198628 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Dickeya

Protein attributes

Sequence length	310 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + 2-dehydro-3-deoxy-D-gluconate = ADP + 6-phospho-2-dehydro-3-deoxy-D-gluconate.
Pathway	Carbohydrate acid metabolism; 2-dehydro-3-deoxy-D-gluconate degradation; D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-gluconate: step 1/2.
Sequence similarities	Belongs to the carbohydrate kinase pfkB family.
Sequence caution	The sequence CAA52961.1 differs from that shown. Reason: Frameshift at position 304.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Gene Ontology (GO)
Molecular function	2-dehydro-3-deoxygluconokinase activity Inferred from electronic annotation. Source: EC ATP binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 310	310	2-dehydro-3-deoxygluconokinase		PRO_0000080086

Sequences

	Sequence		Length	Mass (Da)
	P45416-1 [UniParc]. Last modified October 1, 1996. Version 2. Checksum: 6EB9EF89E0B1F50C	FASTA	310	34,217
	10 20 30 40 50 60 MTTKNIAIIG ECMIELSRKA RISIRGFGGD TLNTAVYISR QVKPDALDVH YVTALGTDSF 70 80 90 100 110 120 SSEMMASWQK EGVKTDLIQR LDNKLPGLYF IETDATGERT FYYWRNDAAA RYWLESPDAD 130 140 150 160 170 180 TISQQLAQFD YIYLSGISLA ILNQASRARL LTVLRACRAN GGKVIFDNNY RPRLWQSKEE 190 200 210 220 230 240 TRQAYSDMLA CTDIAFLTLD DEDMLWGELP VDEVLKRTHG AGVMEVVIKR GADACLVSIQ 250 260 270 280 290 300 GEALLEVPAI KLPKEKVVDT TAAGDSFSAG YLSVRLNGGS AQDAAKRGHL TASTVIQYRG 310 AIIPLEAMPA

References

[1]	"Molecular characterization of the Erwinia chrysanthemi kdgK gene involved in pectin degradation." Hugouvieux-Cotte-Pattat N., Nasser W., Robert-Baudouy J. J. Bacteriol. 176:2386-2392(1994) [PubMed: 8157608] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	Rudd K.E. Unpublished observations (AUG-1996) Cited for: IDENTIFICATION OF PROBABLE FRAMESHIFT.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X75047 Genomic DNA. Translation: CAA52961.1. Frameshift.
PIR	C55215.
3D structure databases
HSSP	HSSP built from PDB template 1DGY based on UniProtKB Q9TVW2.
ModBase	Search...
Family and domain databases
InterPro	IPR011611. Carb/pur_kinase. IPR002173. Carboh/pur_kinase_PfkB_CS. [Graphical view]
Pfam	PF00294. PfkB. 1 hit. [Graphical view]
PROSITE	PS00583. PFKB_KINASES_1. False negative. PS00584. PFKB_KINASES_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KDGK_DICD3

Accession

Primary (citable) accession number: P45416

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	October 1, 1996
Last modified:	September 22, 2009
This is version 51 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)