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Protein

Inner membrane protein YrbG

Gene

yrbG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:YRBG-MONOMER.
ECOL316407:JW3163-MONOMER.

Protein family/group databases

TCDBi2.A.19.5.1. the ca(2+):cation antiporter (caca) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane protein YrbG
Gene namesi
Name:yrbG
Ordered Locus Names:b3196, JW3163
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12802. yrbG.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 55PeriplasmicSequence analysis
Transmembranei6 – 2621HelicalSequence analysisAdd
BLAST
Topological domaini27 – 3711CytoplasmicSequence analysisAdd
BLAST
Transmembranei38 – 5821HelicalSequence analysisAdd
BLAST
Topological domaini59 – 679PeriplasmicSequence analysis
Transmembranei68 – 8821HelicalSequence analysisAdd
BLAST
Topological domaini89 – 10416CytoplasmicSequence analysisAdd
BLAST
Transmembranei105 – 12521HelicalSequence analysisAdd
BLAST
Topological domaini126 – 1261PeriplasmicSequence analysis
Transmembranei127 – 14721HelicalSequence analysisAdd
BLAST
Topological domaini148 – 16922CytoplasmicSequence analysisAdd
BLAST
Transmembranei170 – 19021HelicalSequence analysisAdd
BLAST
Topological domaini191 – 1988PeriplasmicSequence analysis
Transmembranei199 – 21921HelicalSequence analysisAdd
BLAST
Topological domaini220 – 24324CytoplasmicSequence analysisAdd
BLAST
Transmembranei244 – 26421HelicalSequence analysisAdd
BLAST
Topological domaini265 – 2695PeriplasmicSequence analysis
Transmembranei270 – 29021HelicalSequence analysisAdd
BLAST
Topological domaini291 – 30212CytoplasmicSequence analysisAdd
BLAST
Transmembranei303 – 32321HelicalSequence analysisAdd
BLAST
Topological domaini324 – 3252PeriplasmicSequence analysis

GO - Cellular componenti

  • integral component of plasma membrane Source: EcoliWiki
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 325325Inner membrane protein YrbGPRO_0000209507Add
BLAST

Proteomic databases

PaxDbiP45394.
PRIDEiP45394.

Interactioni

Protein-protein interaction databases

BioGridi4261579. 3 interactions.
STRINGi511145.b3196.

Structurei

3D structure databases

ProteinModelPortaliP45394.
SMRiP45394. Positions 19-316.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105FEU. Bacteria.
COG0530. LUCA.
HOGENOMiHOG000274121.
InParanoidiP45394.
KOiK07301.
OMAiEQMAELP.
OrthoDBiEOG6H4K73.
PhylomeDBiP45394.

Family and domain databases

InterProiIPR004481. K/Na/Ca-exchanger.
IPR004837. NaCa_Exmemb.
[Graphical view]
PANTHERiPTHR10846. PTHR10846. 1 hit.
PfamiPF01699. Na_Ca_ex. 2 hits.
[Graphical view]
TIGRFAMsiTIGR00367. TIGR00367. 1 hit.

Sequencei

Sequence statusi: Complete.

P45394-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLATALLIV GLLLVVYSAD RLVFAASILC RTFGIPPLII GMTVVSIGTS
60 70 80 90 100
LPEVIVSLAA SLHEQRDLAV GTALGSNIIN ILLILGLAAL VRPFTVHSDV
110 120 130 140 150
LRRELPLMLL VSVVAGSVLY DGQLSRSDGI FLLFLAVLWL LFIVKLARQA
160 170 180 190 200
ERQGTDSLTR EQLAELPRDG GLPVAFLWLG IALIIMPVAT RMVVDNATVL
210 220 230 240 250
ANYFAISELT MGLTAIAIGT SLPELATAIA GVRKGENDIA VGNIIGANIF
260 270 280 290 300
NIVIVLGLPA LITPGEIDPL AYSRDYSVML LVSIIFALLC WRRSPQPGRG
310 320
VGVLLTGGFI VWLAMLYWLS PILVE
Length:325
Mass (Da):34,741
Last modified:November 1, 1995 - v1
Checksum:iBC08E0BBFD56A6C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA57997.1.
U00096 Genomic DNA. Translation: AAC76228.1.
AP009048 Genomic DNA. Translation: BAE77240.1.
PIRiF65110.
RefSeqiNP_417663.1. NC_000913.3.
WP_000922901.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76228; AAC76228; b3196.
BAE77240; BAE77240; BAE77240.
GeneIDi947730.
KEGGiecj:JW3163.
eco:b3196.
PATRICi32121812. VBIEscCol129921_3290.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA57997.1.
U00096 Genomic DNA. Translation: AAC76228.1.
AP009048 Genomic DNA. Translation: BAE77240.1.
PIRiF65110.
RefSeqiNP_417663.1. NC_000913.3.
WP_000922901.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP45394.
SMRiP45394. Positions 19-316.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261579. 3 interactions.
STRINGi511145.b3196.

Protein family/group databases

TCDBi2.A.19.5.1. the ca(2+):cation antiporter (caca) family.

Proteomic databases

PaxDbiP45394.
PRIDEiP45394.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76228; AAC76228; b3196.
BAE77240; BAE77240; BAE77240.
GeneIDi947730.
KEGGiecj:JW3163.
eco:b3196.
PATRICi32121812. VBIEscCol129921_3290.

Organism-specific databases

EchoBASEiEB2654.
EcoGeneiEG12802. yrbG.

Phylogenomic databases

eggNOGiENOG4105FEU. Bacteria.
COG0530. LUCA.
HOGENOMiHOG000274121.
InParanoidiP45394.
KOiK07301.
OMAiEQMAELP.
OrthoDBiEOG6H4K73.
PhylomeDBiP45394.

Enzyme and pathway databases

BioCyciEcoCyc:YRBG-MONOMER.
ECOL316407:JW3163-MONOMER.

Miscellaneous databases

PROiP45394.

Family and domain databases

InterProiIPR004481. K/Na/Ca-exchanger.
IPR004837. NaCa_Exmemb.
[Graphical view]
PANTHERiPTHR10846. PTHR10846. 1 hit.
PfamiPF01699. Na_Ca_ex. 2 hits.
[Graphical view]
TIGRFAMsiTIGR00367. TIGR00367. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYRBG_ECOLI
AccessioniPrimary (citable) accession number: P45394
Secondary accession number(s): Q2M916
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: February 17, 2016
This is version 118 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.