P45310 (MOAC_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cyclic pyranopterin monophosphate synthase accessory protein

Alternative name(s):
Molybdenum cofactor biosynthesis protein C

Gene names

Name:	moaC
Ordered Locus Names:	HI_1675

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus influenzae

Protein attributes

Sequence length	160 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Together with MoaA, is involved in the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) By similarity. HAMAP-Rule MF_01224_B
Pathway	Cofactor biosynthesis; molybdopterin biosynthesis. HAMAP-Rule MF_01224_B
Sequence similarities	Belongs to the MoaC family.

Ontologies

Keywords
Biological process	Molybdenum cofactor biosynthesis
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	Mo-molybdopterin cofactor biosynthetic process Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 160	160	Cyclic pyranopterin monophosphate synthase accessory protein HAMAP-Rule MF_01224_B		PRO_0000097803
Sites
	Active site	128	1	Potential

Sequences

	Sequence		Length	Mass (Da)
	P45310 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: C588D33869C7DCED	FASTA	160	17,467
	10 20 30 40 50 60 MTTFTHINSQ GEANMVDVSA KAETVREARA EAIVTMSKET LSMIVEGKHH KGDVFATARI 70 80 90 100 110 120 AGIQAAKRTW ELIPLCHPLL LSKVEVNLEP LLETNQVRIQ SLCKLTGKTG VEMEALTAAS 130 140 150 160 VAALTIYDMC KAVQKDIVIE HVRLLEKSGG KSGHFIAEEK

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC23320.1.
PIR	A64136.
RefSeq	NP_439817.1. NC_000907.1.
3D structure databases
ProteinModelPortal	P45310.
SMR	P45310. Positions 11-150.
ModBase	Search...
Protein-protein interaction databases
STRING	71421.HI1675.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC23320; AAC23320; HI_1675.
GeneID	950864.
KEGG	hin:HI1675.
PATRIC	20192101. VBIHaeInf48452_1754.
Phylogenomic databases
eggNOG	COG0315.
KO	K03637.
OMA	AEAFVEM.
ProtClustDB	PRK09364.
Enzyme and pathway databases
UniPathway	UPA00344.
Family and domain databases
Gene3D	3.30.70.640. 1 hit.
HAMAP	MF_01224_B. MoaC_B.
InterPro	IPR023045. Mo_CF_biosynth-C. IPR023046. Mo_CF_biosynth-C_bac. IPR002820. Mopterin_CF_biosynth-C_dom. [Graphical view]
PANTHER	PTHR26250. PTHR26250. 1 hit.
Pfam	PF01967. MoaC. 1 hit. [Graphical view]
SUPFAM	SSF55040. MoaC. 1 hit.
TIGRFAMs	TIGR00581. moaC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MOAC_HAEIN

Accession

Primary (citable) accession number: P45310

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	May 1, 2013
This is version 84 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program