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P45309 (MOAD_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Molybdopterin synthase sulfur carrier subunit
Alternative name(s):
MPT synthase subunit 1
Molybdenum cofactor biosynthesis protein D
Molybdopterin-converting factor small subunit
Molybdopterin-converting factor subunit 1
Sulfur carrier protein MoaD
Gene names
Name:moaD
Ordered Locus Names:HI_1674
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length81 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin By similarity.

Pathway

Cofactor biosynthesis; molybdopterin biosynthesis.

Subunit structure

Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Forms a stable heterotetrameric complex of 2 MoaD and 2 MoeB during adenylation of MoaD by MoeB. During catalysis MoaD shuttles between the two heterotetrameric complexes By similarity.

Sequence similarities

Belongs to the MoaD family.

Ontologies

Keywords
   Biological processMolybdenum cofactor biosynthesis
   LigandNucleotide-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processMo-molybdopterin cofactor biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionnucleotide binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 8181Molybdopterin synthase sulfur carrier subunit
PRO_0000209132

Amino acid modifications

Modified residue8111-thioglycine; alternate By similarity
Modified residue811Glycyl adenylate; alternate By similarity

Sequences

Sequence LengthMass (Da)Tools
P45309 [UniParc].

Last modified November 1, 1997. Version 2.
Checksum: 35D1440F82456F22

FASTA818,826
        10         20         30         40         50         60 
MLNVLFFAQT RELIGVDAIQ LEDDFATAEA VREHLAQKGD KWALALEKGK LLVAINQTLM 

        70         80 
PLESAVKNGD EIAFFPPVTG G 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L42023 Genomic DNA. Translation: AAC23319.1.
PIRA59368.
RefSeqNP_439816.1. NC_000907.1.

3D structure databases

ProteinModelPortalP45309.
SMRP45309. Positions 1-81.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING71421.HI1674.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC23319; AAC23319; HI_1674.
GeneID950503.
KEGGhin:HI1674.
PATRIC20192099. VBIHaeInf48452_1753.

Phylogenomic databases

eggNOGCOG1977.
KOK03636.
OMATISSWDT.
OrthoDBEOG6KMBD9.
PhylomeDBP45309.

Enzyme and pathway databases

UniPathwayUPA00344.

Family and domain databases

Gene3D3.10.20.30. 1 hit.
InterProIPR012675. Beta-grasp_dom.
IPR010034. Mopterin_su_1.
IPR016155. Mopterin_synth/thiamin_S_b.
IPR003749. ThiS/MoaD.
[Graphical view]
PfamPF02597. ThiS. 1 hit.
[Graphical view]
SUPFAMSSF54285. SSF54285. 1 hit.
TIGRFAMsTIGR01682. moaD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMOAD_HAEIN
AccessionPrimary (citable) accession number: P45309
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1997
Last modified: July 9, 2014
This is version 88 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names