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P45294 (PDXT_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine amidotransferase subunit PdxT

EC=2.6.-.-
Alternative name(s):
Glutamine amidotransferase glutaminase subunit PdxT
Gene names
Name:pdxT
Ordered Locus Names:HI_1648
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length192 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS By similarity. HAMAP-Rule MF_01615

Pathway

Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis. HAMAP-Rule MF_01615

Subunit structure

Forms a complex with PdxS By similarity. HAMAP-Rule MF_01615

Sequence similarities

Belongs to the glutamine amidotransferase PdxT/SNO family.

Sequence caution

The sequence AAC23295.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   DomainGlutamine amidotransferase
   LigandPyridoxal phosphate
   Molecular functionTransferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglutamine catabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

pyridoxal phosphate biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functiontransferase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 192192Glutamine amidotransferase subunit PdxT HAMAP-Rule MF_01615
PRO_0000135641

Sites

Active site821Nucleophile By similarity
Active site1721 By similarity
Active site1741 By similarity
Binding site1091Glutamine Potential

Sequences

Sequence LengthMass (Da)Tools
P45294 [UniParc].

Last modified July 5, 2005. Version 2.
Checksum: 52297D26C0EE5579

FASTA19221,070
        10         20         30         40         50         60 
MKIGILALQG AFAEHARMLE KLGIESVELR NLKNFQQHYS DLSGLILPGG ESTAIGKLLR 

        70         80         90        100        110        120 
ELYMLEPIKQ AISSGFPVFG TCAGLILLAK EITSQKESHF GTMDIVVERN AYGRQLGSFY 

       130        140        150        160        170        180 
TEADCKGVGK IPMTFIRGPI ISSVGKKVNI LATVNNKIVA AQEKNMLVTS FHPELTNNLS 

       190 
LHKYFIDICK VA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L42023 Genomic DNA. Translation: AAC23295.1. Different initiation.
PIRG64173.
RefSeqNP_439790.2. NC_000907.1.

3D structure databases

ProteinModelPortalP45294.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING71421.HI1648.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC23295; AAC23295; HI_1648.
GeneID950854.
KEGGhin:HI1648.
PATRIC20192041. VBIHaeInf48452_1724.

Phylogenomic databases

eggNOGCOG0311.
KOK08681.
OMAGMIMLAD.
OrthoDBEOG66F0BW.
ProtClustDBPRK13525.

Enzyme and pathway databases

UniPathwayUPA00245.

Family and domain databases

HAMAPMF_01615. PdxT.
InterProIPR002161. Glutamine_amidoTferase_suPdxT.
IPR021196. PdxT/SNO_CS.
[Graphical view]
PfamPF01174. SNO. 1 hit.
[Graphical view]
PIRSFPIRSF005639. Glut_amidoT_SNO. 1 hit.
TIGRFAMsTIGR03800. PLP_synth_Pdx2. 1 hit.
PROSITEPS01236. PDXT_SNO_1. 1 hit.
PS51130. PDXT_SNO_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePDXT_HAEIN
AccessionPrimary (citable) accession number: P45294
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: July 5, 2005
Last modified: February 19, 2014
This is version 76 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names