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P45260

- ILVH_HAEIN

UniProt

P45260 - ILVH_HAEIN

Protein

Acetolactate synthase small subunit

Gene

ilvH

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 95 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    2 pyruvate = 2-acetolactate + CO2.

    Pathwayi

    GO - Molecular functioni

    1. acetolactate synthase activity Source: UniProtKB-EC
    2. amino acid binding Source: InterPro

    GO - Biological processi

    1. isoleucine biosynthetic process Source: UniProtKB-UniPathway
    2. valine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Amino-acid biosynthesis, Branched-chain amino acid biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00047; UER00055.
    UPA00049; UER00059.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acetolactate synthase small subunit (EC:2.2.1.6)
    Alternative name(s):
    Acetohydroxy-acid synthase small subunit
    Short name:
    AHAS
    Short name:
    ALS
    Gene namesi
    Name:ilvH
    Ordered Locus Names:HI_1584
    OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
    Taxonomic identifieri71421 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000000579: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 163163Acetolactate synthase small subunitPRO_0000151412Add
    BLAST

    Proteomic databases

    PRIDEiP45260.

    Interactioni

    Subunit structurei

    Dimer of large and small chains.By similarity

    Protein-protein interaction databases

    STRINGi71421.HI1584.

    Structurei

    3D structure databases

    ProteinModelPortaliP45260.
    SMRiP45260. Positions 2-160.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini4 – 7976ACTPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 ACT domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0440.
    KOiK01653.
    OMAiAARIKIP.
    OrthoDBiEOG6X3W8W.
    PhylomeDBiP45260.

    Family and domain databases

    InterProiIPR004789. Acetalactate_synth_ssu.
    IPR019455. Acetolactate_synth_ssu_C.
    IPR002912. ACT_dom.
    [Graphical view]
    PfamiPF10369. ALS_ss_C. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00119. acolac_sm. 1 hit.
    PROSITEiPS51671. ACT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P45260-1 [UniParc]FASTAAdd to Basket

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    MRRILSVLLE NESGALSRVV GLFSQRAFNI ESLTVAPTDD PTLSRMTIEA    50
    VGDAQALEQI EKQLHKLVDV FKVVNLSEQE HIEREIVLAK VRAVGSSRDE 100
    IKRLADIFRG QIVDVTPKSY TIQLSGTNDK VDAFISALKE ETTLLEIVRS 150
    GLISVSRGEK NIL 163
    Length:163
    Mass (Da):18,087
    Last modified:November 1, 1995 - v1
    Checksum:i4F6AFBE71FDD8A32
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC23232.1.
    PIRiB64131.
    RefSeqiNP_439729.1. NC_000907.1.

    Genome annotation databases

    EnsemblBacteriaiAAC23232; AAC23232; HI_1584.
    GeneIDi950447.
    KEGGihin:HI1584.
    PATRICi20191901. VBIHaeInf48452_1658.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC23232.1 .
    PIRi B64131.
    RefSeqi NP_439729.1. NC_000907.1.

    3D structure databases

    ProteinModelPortali P45260.
    SMRi P45260. Positions 2-160.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 71421.HI1584.

    Proteomic databases

    PRIDEi P45260.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC23232 ; AAC23232 ; HI_1584 .
    GeneIDi 950447.
    KEGGi hin:HI1584.
    PATRICi 20191901. VBIHaeInf48452_1658.

    Phylogenomic databases

    eggNOGi COG0440.
    KOi K01653.
    OMAi AARIKIP.
    OrthoDBi EOG6X3W8W.
    PhylomeDBi P45260.

    Enzyme and pathway databases

    UniPathwayi UPA00047 ; UER00055 .
    UPA00049 ; UER00059 .

    Family and domain databases

    InterProi IPR004789. Acetalactate_synth_ssu.
    IPR019455. Acetolactate_synth_ssu_C.
    IPR002912. ACT_dom.
    [Graphical view ]
    Pfami PF10369. ALS_ss_C. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00119. acolac_sm. 1 hit.
    PROSITEi PS51671. ACT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

    Entry informationi

    Entry nameiILVH_HAEIN
    AccessioniPrimary (citable) accession number: P45260
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 95 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Haemophilus influenzae
      Haemophilus influenzae (strain Rd): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3