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P45260

- ILVH_HAEIN

UniProt

P45260 - ILVH_HAEIN

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Protein

Acetolactate synthase small subunit

Gene
ilvH, HI_1584
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

2 pyruvate = 2-acetolactate + CO2.

Pathwayi

GO - Molecular functioni

  1. acetolactate synthase activity Source: UniProtKB-EC
  2. amino acid binding Source: InterPro

GO - Biological processi

  1. isoleucine biosynthetic process Source: UniProtKB-UniPathway
  2. valine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Branched-chain amino acid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00047; UER00055.
UPA00049; UER00059.

Names & Taxonomyi

Protein namesi
Recommended name:
Acetolactate synthase small subunit (EC:2.2.1.6)
Alternative name(s):
Acetohydroxy-acid synthase small subunit
Short name:
AHAS
Short name:
ALS
Gene namesi
Name:ilvH
Ordered Locus Names:HI_1584
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 163163Acetolactate synthase small subunitPRO_0000151412Add
BLAST

Proteomic databases

PRIDEiP45260.

Interactioni

Subunit structurei

Dimer of large and small chains By similarity.

Protein-protein interaction databases

STRINGi71421.HI1584.

Structurei

3D structure databases

ProteinModelPortaliP45260.
SMRiP45260. Positions 2-160.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 7976ACTAdd
BLAST

Sequence similaritiesi

Contains 1 ACT domain.

Phylogenomic databases

eggNOGiCOG0440.
KOiK01653.
OMAiAARIKIP.
OrthoDBiEOG6X3W8W.
PhylomeDBiP45260.

Family and domain databases

InterProiIPR004789. Acetalactate_synth_ssu.
IPR019455. Acetolactate_synth_ssu_C.
IPR002912. ACT_dom.
[Graphical view]
PfamiPF10369. ALS_ss_C. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00119. acolac_sm. 1 hit.
PROSITEiPS51671. ACT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P45260-1 [UniParc]FASTAAdd to Basket

« Hide

MRRILSVLLE NESGALSRVV GLFSQRAFNI ESLTVAPTDD PTLSRMTIEA    50
VGDAQALEQI EKQLHKLVDV FKVVNLSEQE HIEREIVLAK VRAVGSSRDE 100
IKRLADIFRG QIVDVTPKSY TIQLSGTNDK VDAFISALKE ETTLLEIVRS 150
GLISVSRGEK NIL 163
Length:163
Mass (Da):18,087
Last modified:November 1, 1995 - v1
Checksum:i4F6AFBE71FDD8A32
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC23232.1.
PIRiB64131.
RefSeqiNP_439729.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC23232; AAC23232; HI_1584.
GeneIDi950447.
KEGGihin:HI1584.
PATRICi20191901. VBIHaeInf48452_1658.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC23232.1 .
PIRi B64131.
RefSeqi NP_439729.1. NC_000907.1.

3D structure databases

ProteinModelPortali P45260.
SMRi P45260. Positions 2-160.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 71421.HI1584.

Proteomic databases

PRIDEi P45260.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC23232 ; AAC23232 ; HI_1584 .
GeneIDi 950447.
KEGGi hin:HI1584.
PATRICi 20191901. VBIHaeInf48452_1658.

Phylogenomic databases

eggNOGi COG0440.
KOi K01653.
OMAi AARIKIP.
OrthoDBi EOG6X3W8W.
PhylomeDBi P45260.

Enzyme and pathway databases

UniPathwayi UPA00047 ; UER00055 .
UPA00049 ; UER00059 .

Family and domain databases

InterProi IPR004789. Acetalactate_synth_ssu.
IPR019455. Acetolactate_synth_ssu_C.
IPR002912. ACT_dom.
[Graphical view ]
Pfami PF10369. ALS_ss_C. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00119. acolac_sm. 1 hit.
PROSITEi PS51671. ACT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiILVH_HAEIN
AccessioniPrimary (citable) accession number: P45260
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: July 9, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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