P45244 (Y1542_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative NAD(P)H nitroreductase HI_1542
EC=1.-.-.-

Gene names

Ordered Locus Names:

HI_1542

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus influenzae

Protein attributes

Sequence length	184 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Binds 1 FMN per subunit By similarity.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the nitroreductase family.

Ontologies

Keywords
Ligand	FMN Flavoprotein NAD NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 184	184	Putative NAD(P)H nitroreductase HI_1542		PRO_0000169004
Regions
	Nucleotide binding	10 – 12	3	FMN By similarity
	Nucleotide binding	122 – 127	6	NAD or NADP Potential
	Nucleotide binding	132 – 134	3	FMN By similarity
Sites
	Binding site	35	1	FMN; shared with dimeric partner By similarity
	Binding site	39	1	FMN; shared with dimeric partner By similarity

Sequences

	Sequence		Length	Mass (Da)
	P45244 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: F2EBDC99020C1025	FASTA	184	20,400
	10 20 30 40 50 60 MDALTLLTTR KSNKKLTAPA PNAEQLERIF EAAMRAPDHG KLHPYHFIVM ENESLNKLET 70 80 90 100 110 120 LLKAAVVEFD LGEEKLMKAE NLAHRAPMVI GVVAKIDPTI AKVPGWEQML SAGCATYGLQ 130 140 150 160 170 180 LAAQAQGFDN VWISGKWVNG TALREAFGCR EQDRVIALVM IGTGMEKAER ECRVIDTKDF VTYL

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC23192.1.
PIR	D64172.
RefSeq	NP_439691.1. NC_000907.1.
3D structure databases
ProteinModelPortal	P45244.
ModBase	Search...
Protein-protein interaction databases
STRING	71421.HI1542.
Protocols and materials databases
DNASU	950405.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC23192; AAC23192; HI_1542.
GeneID	950405.
KEGG	hin:HI1542.
PATRIC	20191809. VBIHaeInf48452_1613.
Phylogenomic databases
eggNOG	COG0778.
OMA	QGIGAVW.
ProtClustDB	CLSK808537.
Family and domain databases
Gene3D	3.40.109.10. 1 hit.
InterPro	IPR000415. Nitroreductase-like. IPR026021. YdjA-like. [Graphical view]
Pfam	PF00881. Nitroreductase. 1 hit. [Graphical view]
PIRSF	PIRSF000232. YdjA. 1 hit.
SUPFAM	SSF55469. Nitroreductase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Y1542_HAEIN

Accession

Primary (citable) accession number: P45244

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	May 1, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program