P45215 (Y1459_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable RNA polymerase sigma factor HI_1459

Gene names

Ordered Locus Names:

HI_1459

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus influenzae

Protein attributes

Sequence length	194 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the sigma-70 factor family. ECF subfamily.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Ligand	DNA-binding
Molecular function	Sigma factor
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA-dependent transcription, initiation Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro sigma factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 194	194	Probable RNA polymerase sigma factor HI_1459		PRO_0000094020
Regions
	DNA binding	161 – 180	20	H-T-H motif By similarity
	Motif	45 – 58	14	Polymerase core binding Potential

Sequences

	Sequence		Length	Mass (Da)
	P45215 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 9E55F57235B43CE1	FASTA	194	22,843
	10 20 30 40 50 60 MSFISYISFK GIKMNVISDL ELQQIRTQML TFAQLQVNQA DLAEDLVQEA FLSAFKNLAN 70 80 90 100 110 120 FKRQSAFKTW IFAILKNKII DYLRQKGRFV LESELEDENT NNSFFDEKGH WKPEYHPSEL 130 140 150 160 170 180 QGEEETVYSD EFWLIFETCL NCLPAKQAKI FMMREFLELS SEEICQETHL TSSNLHTTLY 190 RARLQLQNCL SKKL

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC23107.1.
PIR	G64124.
RefSeq	NP_439610.2. NC_000907.1.
3D structure databases
ProteinModelPortal	P45215.
ModBase	Search...
Protein-protein interaction databases
STRING	71421.HI1459.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC23107; AAC23107; HI_1459.
GeneID	950350.
KEGG	hin:HI1459.
PATRIC	20191625. VBIHaeInf48452_1522.
Phylogenomic databases
eggNOG	COG1595.
KO	K03088.
OMA	ALKTWIF.
ProtClustDB	PRK12530.
Family and domain databases
Gene3D	1.10.10.10. 1 hit.
InterPro	IPR014289. RNA_pol_sigma-24-rel. IPR014284. RNA_pol_sigma-70_dom. IPR000838. RNA_pol_sigma70_ECF_CS. IPR007627. RNA_pol_sigma70_r2. IPR013249. RNA_pol_sigma70_r4_t2. IPR013325. RNA_pol_sigma_r2. IPR013324. RNA_pol_sigma_r3_r4. IPR011991. WHTH_DNA-bd_dom. [Graphical view]
Pfam	PF04542. Sigma70_r2. 1 hit. PF08281. Sigma70_r4_2. 1 hit. [Graphical view]
SUPFAM	SSF88946. Sigma_r2. 1 hit. SSF88659. Sigma_r3_r4. 1 hit.
TIGRFAMs	TIGR02943. Sig70_famx1. 1 hit. TIGR02937. sigma70-ECF. 1 hit.
PROSITE	PS01063. SIGMA70_ECF. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y1459_HAEIN

Accession

Primary (citable) accession number: P45215

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	May 1, 2013
This is version 89 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program