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P45199 (FNR_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Anaerobic regulatory protein
Gene names
Name:fnr
Ordered Locus Names:HI_1425
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length257 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

It is involved in the activation of genes necessary for anaerobic respiration.

Cofactor

Binds 1 4Fe-4S cluster per subunit By similarity.

Subunit structure

Homodimer By similarity.

Subcellular location

Cytoplasm Probable.

Sequence similarities

Contains 1 cyclic nucleotide-binding domain.

Contains 1 HTH crp-type DNA-binding domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 257257Anaerobic regulatory protein
PRO_0000100177

Regions

Domain167 – 24074HTH crp-type
DNA binding200 – 21920H-T-H motif Potential
Region23 – 3210Essential for the oxygen-regulated activity By similarity
Region143 – 16220Dimerization Potential

Sites

Metal binding231Iron-sulfur (4Fe-4S) Potential
Metal binding261Iron-sulfur (4Fe-4S) Potential
Metal binding321Iron-sulfur (4Fe-4S) Potential
Metal binding1251Iron-sulfur (4Fe-4S) Potential

Sequences

Sequence LengthMass (Da)Tools
P45199 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 2D81E3CE180D5137

FASTA25728,595
        10         20         30         40         50         60 
MKNFVAGAQS GRKIQSGGCA IHCQDCSISQ LCIPFTLNEQ ELDQLDNIIE RKKPIQKSQV 

        70         80         90        100        110        120 
LFKAGDSLNS IYAIRSGTIK SYTISESGEE QITSFHLPGD LVGFDAITQM QHPSFAQALE 

       130        140        150        160        170        180 
TAMVCEIPFD ILDDLAGKMP KLRQQILRLM SSEIKSDQEM ILLLSKMNAE ERLAAFIHNL 

       190        200        210        220        230        240 
SKRYSARGFS AREFRLTMTR GDIGNYLGLT VETISRLLGR FQKLGVISVQ GKYITINDLN 

       250 
GLIELTGTNK TKITLVK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L42023 Genomic DNA. Translation: AAC23062.1.
PIRE64122.
RefSeqNP_439574.1. NC_000907.1.

3D structure databases

ProteinModelPortalP45199.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING71421.HI1425.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC23062; AAC23062; HI_1425.
GeneID950327.
KEGGhin:HI1425.
PATRIC20191545. VBIHaeInf48452_1482.

Phylogenomic databases

eggNOGCOG0664.
KOK01420.
OMAAIRTGFF.
OrthoDBEOG6RVFWF.
ProtClustDBPRK11161.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP_2.
IPR014710. RmlC-like_jellyroll.
IPR001808. Tscrpt_reg_HTH_Crp.
IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF00027. cNMP_binding. 1 hit.
PF00325. Crp. 1 hit.
[Graphical view]
PRINTSPR00034. HTHCRP.
SMARTSM00100. cNMP. 1 hit.
SM00419. HTH_CRP. 1 hit.
[Graphical view]
SUPFAMSSF51206. SSF51206. 1 hit.
PROSITEPS50042. CNMP_BINDING_3. 1 hit.
PS00042. HTH_CRP_1. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFNR_HAEIN
AccessionPrimary (citable) accession number: P45199
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: February 19, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names