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P45189

- PHOB_HAEIN

UniProt

P45189 - PHOB_HAEIN

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Protein

Phosphate regulon transcriptional regulatory protein PhoB

Gene

phoB

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited (By similarity).By similarity

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. phosphorelay response regulator activity Source: InterPro

GO - Biological processi

  1. phosphate ion transport Source: UniProtKB-KW
  2. regulation of transcription, DNA-templated Source: UniProtKB-KW
  3. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Phosphate transport, Transcription, Transcription regulation, Transport, Two-component regulatory system

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphate regulon transcriptional regulatory protein PhoB
Gene namesi
Name:phoB
Ordered Locus Names:HI_1379
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 231231Phosphate regulon transcriptional regulatory protein PhoBPRO_0000081188Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei52 – 5214-aspartylphosphatePROSITE-ProRule annotation

Post-translational modificationi

Phosphorylated by PhoR.By similarity

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi71421.HI1379.

Structurei

3D structure databases

ProteinModelPortaliP45189.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 119119Response regulatoryPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 response regulatory domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0745.
KOiK07657.
OMAiDWMIPGG.
OrthoDBiEOG6G4VQG.
PhylomeDBiP45189.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR011006. CheY-like_superfamily.
IPR001867. Sig_transdc_resp-reg_C.
IPR011879. Sig_transdc_resp-reg_PhoB.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00072. Response_reg. 1 hit.
PF00486. Trans_reg_C. 1 hit.
[Graphical view]
SMARTiSM00448. REC. 1 hit.
SM00862. Trans_reg_C. 1 hit.
[Graphical view]
SUPFAMiSSF52172. SSF52172. 1 hit.
TIGRFAMsiTIGR02154. PhoB. 1 hit.
PROSITEiPS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P45189 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTRKILIVED ECAIREMIAL FLSQKYYDVI EASDFKTAIN KIKENPKLIL
60 70 80 90 100
LDWMLPGRSG IQFIQYIKKQ ESYAAIPIIM LTAKSTEEDC IACLNAGADD
110 120 130 140 150
YITKPFSPQI LLARIEAVWR RIYEQQSQFI QIDELSIDEN AQRVFFQQQE
160 170 180 190 200
INLSSTEFKL LHFFMRHPEK VYSREQLLNR IWHNDLEVEY RTVDSYIRRL
210 220 230
RRNLAPFQCE HYIQTVRGSG YRFSSYLRDK Q
Length:231
Mass (Da):27,508
Last modified:November 1, 1995 - v1
Checksum:iB90BF5FDD6BF414B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC23025.1.
PIRiF64120.
RefSeqiNP_439531.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC23025; AAC23025; HI_1379.
GeneIDi950671.
KEGGihin:HI1379.
PATRICi20191447. VBIHaeInf48452_1434.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC23025.1 .
PIRi F64120.
RefSeqi NP_439531.1. NC_000907.1.

3D structure databases

ProteinModelPortali P45189.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 71421.HI1379.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC23025 ; AAC23025 ; HI_1379 .
GeneIDi 950671.
KEGGi hin:HI1379.
PATRICi 20191447. VBIHaeInf48452_1434.

Phylogenomic databases

eggNOGi COG0745.
KOi K07657.
OMAi DWMIPGG.
OrthoDBi EOG6G4VQG.
PhylomeDBi P45189.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR011006. CheY-like_superfamily.
IPR001867. Sig_transdc_resp-reg_C.
IPR011879. Sig_transdc_resp-reg_PhoB.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00072. Response_reg. 1 hit.
PF00486. Trans_reg_C. 1 hit.
[Graphical view ]
SMARTi SM00448. REC. 1 hit.
SM00862. Trans_reg_C. 1 hit.
[Graphical view ]
SUPFAMi SSF52172. SSF52172. 1 hit.
TIGRFAMsi TIGR02154. PhoB. 1 hit.
PROSITEi PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiPHOB_HAEIN
AccessioniPrimary (citable) accession number: P45189
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: October 29, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3