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P45189

- PHOB_HAEIN

UniProt

P45189 - PHOB_HAEIN

Protein

Phosphate regulon transcriptional regulatory protein PhoB

Gene

phoB

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 96 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited By similarity.By similarity

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. phosphorelay response regulator activity Source: InterPro

    GO - Biological processi

    1. phosphate ion transport Source: UniProtKB-KW
    2. regulation of transcription, DNA-templated Source: UniProtKB-KW
    3. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Activator

    Keywords - Biological processi

    Phosphate transport, Transcription, Transcription regulation, Transport, Two-component regulatory system

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphate regulon transcriptional regulatory protein PhoB
    Gene namesi
    Name:phoB
    Ordered Locus Names:HI_1379
    OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
    Taxonomic identifieri71421 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000000579: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 231231Phosphate regulon transcriptional regulatory protein PhoBPRO_0000081188Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei52 – 5214-aspartylphosphatePROSITE-ProRule annotation

    Post-translational modificationi

    Phosphorylated by PhoR.By similarity

    Keywords - PTMi

    Phosphoprotein

    Interactioni

    Protein-protein interaction databases

    STRINGi71421.HI1379.

    Structurei

    3D structure databases

    ProteinModelPortaliP45189.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini1 – 119119Response regulatoryPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 response regulatory domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0745.
    KOiK07657.
    OMAiDWMIPGG.
    OrthoDBiEOG6G4VQG.
    PhylomeDBiP45189.

    Family and domain databases

    Gene3Di1.10.10.10. 1 hit.
    InterProiIPR011006. CheY-like_superfamily.
    IPR001867. Sig_transdc_resp-reg_C.
    IPR011879. Sig_transdc_resp-reg_PhoB.
    IPR001789. Sig_transdc_resp-reg_receiver.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PfamiPF00072. Response_reg. 1 hit.
    PF00486. Trans_reg_C. 1 hit.
    [Graphical view]
    SMARTiSM00448. REC. 1 hit.
    SM00862. Trans_reg_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF52172. SSF52172. 1 hit.
    TIGRFAMsiTIGR02154. PhoB. 1 hit.
    PROSITEiPS50110. RESPONSE_REGULATORY. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P45189-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTRKILIVED ECAIREMIAL FLSQKYYDVI EASDFKTAIN KIKENPKLIL    50
    LDWMLPGRSG IQFIQYIKKQ ESYAAIPIIM LTAKSTEEDC IACLNAGADD 100
    YITKPFSPQI LLARIEAVWR RIYEQQSQFI QIDELSIDEN AQRVFFQQQE 150
    INLSSTEFKL LHFFMRHPEK VYSREQLLNR IWHNDLEVEY RTVDSYIRRL 200
    RRNLAPFQCE HYIQTVRGSG YRFSSYLRDK Q 231
    Length:231
    Mass (Da):27,508
    Last modified:November 1, 1995 - v1
    Checksum:iB90BF5FDD6BF414B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC23025.1.
    PIRiF64120.
    RefSeqiNP_439531.1. NC_000907.1.

    Genome annotation databases

    EnsemblBacteriaiAAC23025; AAC23025; HI_1379.
    GeneIDi950671.
    KEGGihin:HI1379.
    PATRICi20191447. VBIHaeInf48452_1434.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC23025.1 .
    PIRi F64120.
    RefSeqi NP_439531.1. NC_000907.1.

    3D structure databases

    ProteinModelPortali P45189.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 71421.HI1379.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC23025 ; AAC23025 ; HI_1379 .
    GeneIDi 950671.
    KEGGi hin:HI1379.
    PATRICi 20191447. VBIHaeInf48452_1434.

    Phylogenomic databases

    eggNOGi COG0745.
    KOi K07657.
    OMAi DWMIPGG.
    OrthoDBi EOG6G4VQG.
    PhylomeDBi P45189.

    Family and domain databases

    Gene3Di 1.10.10.10. 1 hit.
    InterProi IPR011006. CheY-like_superfamily.
    IPR001867. Sig_transdc_resp-reg_C.
    IPR011879. Sig_transdc_resp-reg_PhoB.
    IPR001789. Sig_transdc_resp-reg_receiver.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    Pfami PF00072. Response_reg. 1 hit.
    PF00486. Trans_reg_C. 1 hit.
    [Graphical view ]
    SMARTi SM00448. REC. 1 hit.
    SM00862. Trans_reg_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52172. SSF52172. 1 hit.
    TIGRFAMsi TIGR02154. PhoB. 1 hit.
    PROSITEi PS50110. RESPONSE_REGULATORY. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

    Entry informationi

    Entry nameiPHOB_HAEIN
    AccessioniPrimary (citable) accession number: P45189
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 96 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Haemophilus influenzae
      Haemophilus influenzae (strain Rd): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3