Reviewed, UniProtKB/Swiss-Prot P45176 (MALQ_HAEIN)

Names and origin

Protein names

Recommended name:
    4-alpha-glucanotransferase
    EC=2.4.1.25
Alternative name(s):
    Amylomaltase
    Disproportionating enzyme
      Short name=D-enzyme

Gene names

Name:	malQ
Ordered Locus Names:	HI1356

Organism

Haemophilus influenzae [Complete proteome] [HAMAP]

Taxonomic identifier

727 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	699 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Transfers a segment of a (1->4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1->4)-alpha-D-glucan.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the disproportionating enzyme family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Cellular component	Cytoplasm
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	4-alpha-glucanotransferase activity Inferred from electronic annotation. Source: EC cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 699	699	4-alpha-glucanotransferase		PRO_0000170126

Sequences

	Sequence		Length	Mass (Da)
	P45176-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 80D6E1D51EC2E1E9	FASTA	699	80,252
	10 20 30 40 50 60 MVSMQISDSL KQKAEKCGIA LSHYDIDGHL IFADEKTVST FVELLQPPPK AKGQFDDVLA 70 80 90 100 110 120 AFENEPIDYR LNRLDLPPSA EYRYQLTDES NAILLEKILS NLSVLSLPPL PFGYYQLSIF 130 140 150 160 170 180 SDTEQYRIRL LISPKTAFQP PVLENKKVWG VNVQLYSLRS EQNWGIGDFG DLAYLIEQSA 190 200 210 220 230 240 KQGADYVGIN PLHLPYPAVP NWASPYSSSS RRWLNFLYLD IPDLPEFKRC RSVQNWFKRE 250 260 270 280 290 300 DIQAKIAALR ESDCVDYSSI LALKLTALEP LFDFFQRSQS VEIVTRRKIF AEYLKNKGEP 310 320 330 340 350 360 LLLQGLFNVL DLQEHADHQA EENTIGWLGW RKEWQHLSAA KRKALLKTHH EKIQFFAWLQ 370 380 390 400 410 420 WLTEEQLSAL QNLCKQSGMK LGIYGDLAVN SSRGSADVWS DPDLYCVNAS IGAPPDPLGP 430 440 450 460 470 480 VGQNWNLPPY NPTVLKARGF APFIDMLCAN MQYFGVLRID HVMGLFRLWW IPKGKTAADG 490 500 510 520 530 540 AYVHYPFDEL MAILAIESVR NECLIIGEDL GTVPDEVRWK LNEFQIFSYF VLYFAQRNGE 550 560 570 580 590 600 FPRISDYPRN AYATIGTHDV PSLQSFWHCR DLELFNQLGI LNGEVLKQKY DQRVMDKQAL 610 620 630 640 650 660 LNSLHRDNYL PPHYEGDALS MAMHDYLNRM IHYYLAESNS RLIGVQLENL LSQEISFNLP 670 680 690 STSNEYPNWC KKLAQPLAFI FSNEALKTFF VQINQGRNV

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L42023 Genomic DNA. Translation: AAC23003.1.
PIR	H64118.
RefSeq	NP_439507.1.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GH77. Glycoside Hydrolase Family 77.
Genome annotation databases
GeneID	950287.
GenomeReviews	Gene locus HI1356 in contig L42023_GR.
KEGG	hin:HI1356.
NMPDR	fig|71421.1.peg.1292.
TIGR	HI1356.
Phylogenomic databases
HOGENOM	P45176.
OMA	WASPYSS.
Enzyme and pathway databases
BioCyc	HINF71421:HI_1356-MON.
BRENDA	2.4.1.25. 109.
Family and domain databases
InterPro	IPR003385. Glyco_hydro_77. IPR013781. Glyco_hydro_sg_catalytic. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
Pfam	PF02446. Glyco_hydro_77. 1 hit. [Graphical view]
TIGRFAMs	TIGR00217. malQ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MALQ_HAEIN

Accession

Primary (citable) accession number: P45176

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	November 3, 2009
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)