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P45107

- PTA_HAEIN

UniProt

P45107 - PTA_HAEIN

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Protein

Phosphate acetyltransferase

Gene

pta

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Involved in acetate metabolism.By similarity

Catalytic activityi

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathwayi

GO - Molecular functioni

  1. phosphate acetyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. acetyl-CoA biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Enzyme and pathway databases

UniPathwayiUPA00340; UER00459.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphate acetyltransferase (EC:2.3.1.8)
Alternative name(s):
Phosphotransacetylase
Gene namesi
Name:pta
Ordered Locus Names:HI_1203
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579: Chromosome

Subcellular locationi

Cytoplasm Curated

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 711711Phosphate acetyltransferasePRO_0000179130Add
BLAST

Proteomic databases

PRIDEiP45107.

Interactioni

Subunit structurei

Homohexamer.By similarity

Protein-protein interaction databases

STRINGi71421.HI1203.

Structurei

3D structure databases

ProteinModelPortaliP45107.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni390 – 711322Phosphate acetyltransferaseAdd
BLAST

Domaini

The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site (By similarity).By similarity

Sequence similaritiesi

In the N-terminal section; belongs to the CobB/CobQ family.Curated
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.Curated

Phylogenomic databases

eggNOGiCOG0280.
KOiK13788.
OMAiKPIAQPH.
OrthoDBiEOG6BKJ5W.
PhylomeDBiP45107.

Family and domain databases

Gene3Di3.40.1390.20. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR027417. P-loop_NTPase.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
IPR028979. Ser_kin/Pase_Hpr_N_like.
[Graphical view]
PfamiPF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
[Graphical view]
PIRSFiPIRSF006107. PhpActrans_proteobac. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF75138. SSF75138. 1 hit.
TIGRFAMsiTIGR00651. pta. 1 hit.

Sequencei

Sequence statusi: Complete.

P45107-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSRTIILIPV STGVGLTSIS LGLIHSLEQK GTKVAFMKPV SQPSTGEDKL
60 70 80 90 100
DRTTSIIRTS TSLETAEPFM LSVAESLIGQ NQSDVLLEKI VANHQQLTKN
110 120 130 140 150
NDIVVVEGLI PTRKHGYANS INYEIAQALD AEIVLVAAPA TETPTELKDR
160 170 180 190 200
VEAAASLFGG KNNPNLLGVV VNKFNAPVDE SGRTRPDLAE IFDSFQHNHI
210 220 230 240 250
SETEVNKLFA GSAIKLLACV PWNANLIATR AIDLVKHLGA SIINEGEINR
260 270 280 290 300
RIRGITFCAR SLPNMVEHFR AGSLLVASAD RPDVLVAAAL AASNGIEIGG
310 320 330 340 350
ILLTGGYKID AQINKLCRPT FEKAKLPIFR IEGNTWQTAL SLQSFNLEVP
360 370 380 390 400
VDDKERIENI KQYISQHFNA DFINNLVADS SRLPRLSPPA FRFQLTELAR
410 420 430 440 450
AAKKRIVLPE GDEPRTIKAA VLCAERGIAE CVLLADPASV QRVAEAQGVK
460 470 480 490 500
LGKGITIINP ADVRENYVDR LVELRKAKGM TETAAREQLE DTVVLGTMML
510 520 530 540 550
EANEVDGLVS GAVHTTANTI RPPMQIIKTA PGSSIVSSIF FMLLPDQVLV
560 570 580 590 600
YGDCAVNPDP TAEQLAEIAI QSADSAKAFG IDPKVAMISY STGTSGSGAD
610 620 630 640 650
VEKVKEATRI AKEKRPDLLI DGPLQYDAAV MEDVARSKAP NSPVAGKATV
660 670 680 690 700
FVFPDLNTGN TTYKAVQRSA DLVSIGPMLQ GMRKPVNDLS RGALVDDIVY
710
TIALTAIQAT Q
Length:711
Mass (Da):76,517
Last modified:January 23, 2007 - v2
Checksum:i4C684C943E2870CB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22857.1.
PIRiB64169.
RefSeqiNP_439359.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22857; AAC22857; HI_1203.
GeneIDi950151.
KEGGihin:HI1203.
PATRICi20191085. VBIHaeInf48452_1255.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22857.1 .
PIRi B64169.
RefSeqi NP_439359.1. NC_000907.1.

3D structure databases

ProteinModelPortali P45107.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 71421.HI1203.

Proteomic databases

PRIDEi P45107.

Protocols and materials databases

DNASUi 950151.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC22857 ; AAC22857 ; HI_1203 .
GeneIDi 950151.
KEGGi hin:HI1203.
PATRICi 20191085. VBIHaeInf48452_1255.

Phylogenomic databases

eggNOGi COG0280.
KOi K13788.
OMAi KPIAQPH.
OrthoDBi EOG6BKJ5W.
PhylomeDBi P45107.

Enzyme and pathway databases

UniPathwayi UPA00340 ; UER00459 .

Family and domain databases

Gene3Di 3.40.1390.20. 1 hit.
3.40.50.300. 1 hit.
InterProi IPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR027417. P-loop_NTPase.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
IPR028979. Ser_kin/Pase_Hpr_N_like.
[Graphical view ]
Pfami PF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
[Graphical view ]
PIRSFi PIRSF006107. PhpActrans_proteobac. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
SSF75138. SSF75138. 1 hit.
TIGRFAMsi TIGR00651. pta. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiPTA_HAEIN
AccessioniPrimary (citable) accession number: P45107
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 23, 2007
Last modified: November 26, 2014
This is version 103 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3