P45053 (OPPC_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Oligopeptide transport system permease protein OppC

Gene names

Name:	oppC
Ordered Locus Names:	HI_1122

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus influenzae

Protein attributes

Sequence length	311 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane By similarity.
Subcellular location	Cell inner membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily. Contains 1 ABC transmembrane type-1 domain.

Ontologies

Keywords
Biological process	Peptide transport Protein transport Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	peptide transport Inferred from electronic annotation. Source: UniProtKB-KW protein transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 311	311	Oligopeptide transport system permease protein OppC		PRO_0000060152
Regions
	Topological domain	1 – 48	48	Cytoplasmic Potential
	Transmembrane	49 – 69	21	Helical; Potential
	Topological domain	70 – 113	44	Periplasmic Potential
	Transmembrane	114 – 134	21	Helical; Potential
	Topological domain	135 – 159	25	Cytoplasmic Potential
	Transmembrane	160 – 180	21	Helical; Potential
	Topological domain	181 – 222	42	Periplasmic Potential
	Transmembrane	223 – 243	21	Helical; Potential
	Topological domain	244 – 246	3	Cytoplasmic Potential
	Transmembrane	247 – 267	21	Helical; Potential
	Topological domain	268 – 278	11	Periplasmic Potential
	Transmembrane	279 – 299	21	Helical; Potential
	Topological domain	300 – 311	12	Cytoplasmic Potential
	Domain	110 – 299	190	ABC transmembrane type-1

Sequences

	Sequence		Length	Mass (Da)
	P45053 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: D55C49A361BED3C8	FASTA	311	34,632
	10 20 30 40 50 60 MTDYRTQPIN QKNADFVEQV ADRIEEMQLE GRSLWQDAKR RFFRNKAAVA SLIILAFIII 70 80 90 100 110 120 FITVAPWFFP FTYEDTDWNM MSAAPTMEGY HFFGTDASGR DLLVRTAIGG RISLLVGIAG 130 140 150 160 170 180 AFISVTIGTI YGAISGYVGG KTDMLMMRFL EILSSFPFMF FVILLVTLFG QNIFLIFIAI 190 200 210 220 230 240 GAIAWLGLAR IVRGQTLSLK NKEFVEAAIV CGVPRRQIIL KHIIPNVLGL VAVYASLEVP 250 260 270 280 290 300 GLILFESFLS FLGLGTQEPM SSWGALLSDG AAQMEVSPWL LIFPAFFLCL TLFCFNFIGD 310 GLRDALDPKD R

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC22776.1.
PIR	D64184.
RefSeq	NP_439279.1. NC_000907.1.
3D structure databases
ProteinModelPortal	P45053.
ModBase	Search...
Protein-protein interaction databases
STRING	71421.HI1122.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC22776; AAC22776; HI_1122.
GeneID	950091.
KEGG	hin:HI1122.
PATRIC	20190917. VBIHaeInf48452_1171.
Phylogenomic databases
eggNOG	COG1173.
KO	K15582.
OMA	RSPWADA.
ProtClustDB	CLSK808487.
Family and domain databases
InterPro	IPR000515. BPD_transp. IPR025966. OppC_N. [Graphical view]
Pfam	PF00528. BPD_transp_1. 1 hit. PF12911. OppC_N. 1 hit. [Graphical view]
PROSITE	PS50928. ABC_TM1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

OPPC_HAEIN

Accession

Primary (citable) accession number: P45053

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	May 1, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program