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P45033

- CCMB_HAEIN

UniProt

P45033 - CCMB_HAEIN

Protein

Heme exporter protein B

Gene

ccmB

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.By similarity

    GO - Molecular functioni

    1. heme transporter activity Source: InterPro

    GO - Biological processi

    1. cytochrome complex assembly Source: UniProtKB-KW

    Keywords - Biological processi

    Cytochrome c-type biogenesis, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Heme exporter protein B
    Alternative name(s):
    Cytochrome c-type biogenesis protein CcmB
    Gene namesi
    Name:ccmB
    Ordered Locus Names:HI_1090
    OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
    Taxonomic identifieri71421 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000000579: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 221221Heme exporter protein BPRO_0000201542Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi71421.HI1090.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei21 – 4121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei46 – 6621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei101 – 12121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei126 – 14621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei157 – 17721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei193 – 21321HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the CcmB/CycW/HelB family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG2386.
    KOiK02194.
    OMAiTGHLLWL.
    OrthoDBiEOG64FKHN.
    PhylomeDBiP45033.

    Family and domain databases

    InterProiIPR003544. Cyt_c_biogenesis_CcmB.
    IPR026031. Cyt_c_CcmB_bac.
    [Graphical view]
    PfamiPF03379. CcmB. 1 hit.
    [Graphical view]
    PIRSFiPIRSF002764. CcmB. 1 hit.
    PRINTSiPR01414. CCMBBIOGNSIS.
    TIGRFAMsiTIGR01190. ccmB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P45033-1 [UniParc]FASTAAdd to Basket

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    MIFLEIIKRE LQIAMRKNAE ILNPLWFFLL VITLFPLVIG PDPKLLSRIA    50
    PGIAWVAALL SALLSFERLF RDDFIDGSLE QLMLTAQPLP MTALAKVVAH 100
    WLLTGLPLIL LSPIAALLLS LEVNIWWALV LTLLLGTPVL SCIGAIGVAL 150
    TVGLRKGGVL LSLLVVPLFI PVLIFASSVL EAAGLNVPYG GQLAILGAMM 200
    VGAVTLSPFA IAAALRISLD N 221
    Length:221
    Mass (Da):23,644
    Last modified:November 1, 1995 - v1
    Checksum:i2FF8EAFDC5228EF8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22747.1.
    PIRiF64166.
    RefSeqiNP_439247.1. NC_000907.1.

    Genome annotation databases

    EnsemblBacteriaiAAC22747; AAC22747; HI_1090.
    GeneIDi950092.
    KEGGihin:HI1090.
    PATRICi20190845. VBIHaeInf48452_1135.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22747.1 .
    PIRi F64166.
    RefSeqi NP_439247.1. NC_000907.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 71421.HI1090.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC22747 ; AAC22747 ; HI_1090 .
    GeneIDi 950092.
    KEGGi hin:HI1090.
    PATRICi 20190845. VBIHaeInf48452_1135.

    Phylogenomic databases

    eggNOGi COG2386.
    KOi K02194.
    OMAi TGHLLWL.
    OrthoDBi EOG64FKHN.
    PhylomeDBi P45033.

    Family and domain databases

    InterProi IPR003544. Cyt_c_biogenesis_CcmB.
    IPR026031. Cyt_c_CcmB_bac.
    [Graphical view ]
    Pfami PF03379. CcmB. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF002764. CcmB. 1 hit.
    PRINTSi PR01414. CCMBBIOGNSIS.
    TIGRFAMsi TIGR01190. ccmB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

    Entry informationi

    Entry nameiCCMB_HAEIN
    AccessioniPrimary (citable) accession number: P45033
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 85 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Haemophilus influenzae
      Haemophilus influenzae (strain Rd): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3