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P45016

- NRFB_HAEIN

UniProt

P45016 - NRFB_HAEIN

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Protein

Cytochrome c-type protein NrfB

Gene
nrfB, HI_1068
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Plays a role in nitrite reduction By similarity.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei65 – 651Heme 1 (covalent) By similarity
Binding sitei68 – 681Heme 1 (covalent) By similarity
Metal bindingi69 – 691Iron (heme 1 axial ligand) By similarity
Binding sitei110 – 1101Heme 2 (covalent) By similarity
Binding sitei113 – 1131Heme 2 (covalent) By similarity
Metal bindingi114 – 1141Iron (heme 2 axial ligand) By similarity
Binding sitei152 – 1521Heme 3 (covalent) By similarity
Binding sitei155 – 1551Heme 3 (covalent) By similarity
Metal bindingi156 – 1561Iron (heme 3 axial ligand) By similarity
Binding sitei177 – 1771Heme 4 (covalent) By similarity
Binding sitei180 – 1801Heme 4 (covalent) By similarity
Metal bindingi181 – 1811Iron (heme 4 axial ligand) By similarity
Binding sitei202 – 2021Heme 5 (covalent) By similarity
Binding sitei205 – 2051Heme 5 (covalent) By similarity
Metal bindingi206 – 2061Iron (heme 5 axial ligand) By similarity

GO - Molecular functioni

  1. heme binding Source: InterPro
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. nitrogen compound metabolic process Source: UniProtKB-UniPathway
  2. oxidation-reduction process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Enzyme and pathway databases

UniPathwayiUPA00045.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c-type protein NrfB
Gene namesi
Name:nrfB
Ordered Locus Names:HI_1068
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579: Chromosome

Subcellular locationi

Periplasm Reviewed prediction

GO - Cellular componenti

  1. periplasmic space Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3939 Reviewed predictionAdd
BLAST
Chaini40 – 226187Cytochrome c-type protein NrfBPRO_0000006586Add
BLAST

Post-translational modificationi

Binds 5 heme groups per subunit By similarity.

Interactioni

Protein-protein interaction databases

STRINGi71421.HI1068.

Structurei

3D structure databases

ProteinModelPortaliP45016.

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG06663.
KOiK04013.
OMAiQEQNQVC.
OrthoDBiEOG62ZHTD.

Family and domain databases

InterProiIPR017564. Cyt_c_NO2Rdtase_pentahaem-su.
IPR011031. Multihaem_cyt.
[Graphical view]
TIGRFAMsiTIGR03146. cyt_nit_nrfB. 1 hit.
PROSITEiPS51008. MULTIHEME_CYTC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P45016-1 [UniParc]FASTAAdd to Basket

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MIFKVKFEVT QMILTSLINK SAKALVIVAF VAAPFLAHAD DAQKPAVHVT    50
YEPQLDNQRD PNQYCAKCHK FDKIDKNQTL DQSGGELHFG KFHGAHLDKK 100
NPNNGKAITC VSCHGNISEN HRRGAKDVMR FEGDIFGNKK PMYSVQEQNQ 150
VCFACHQPDK LREKLWAHDV HAMKLPCASC HTLHPKEDAM KGIQPKQRVK 200
LCVDCHGEQQ KRKAEQDKLI EQKDKL 226
Length:226
Mass (Da):25,664
Last modified:November 1, 1995 - v1
Checksum:i959F2DCEA668030A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC22726.1.
PIRiB64181.
RefSeqiNP_439226.2. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22726; AAC22726; HI_1068.
GeneIDi950046.
KEGGihin:HI1068.
PATRICi20190799. VBIHaeInf48452_1112.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC22726.1 .
PIRi B64181.
RefSeqi NP_439226.2. NC_000907.1.

3D structure databases

ProteinModelPortali P45016.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 71421.HI1068.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC22726 ; AAC22726 ; HI_1068 .
GeneIDi 950046.
KEGGi hin:HI1068.
PATRICi 20190799. VBIHaeInf48452_1112.

Phylogenomic databases

eggNOGi NOG06663.
KOi K04013.
OMAi QEQNQVC.
OrthoDBi EOG62ZHTD.

Enzyme and pathway databases

UniPathwayi UPA00045 .

Family and domain databases

InterProi IPR017564. Cyt_c_NO2Rdtase_pentahaem-su.
IPR011031. Multihaem_cyt.
[Graphical view ]
TIGRFAMsi TIGR03146. cyt_nit_nrfB. 1 hit.
PROSITEi PS51008. MULTIHEME_CYTC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiNRFB_HAEIN
AccessioniPrimary (citable) accession number: P45016
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 14, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways

External Data

Dasty 3

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