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P45016

- NRFB_HAEIN

UniProt

P45016 - NRFB_HAEIN

Protein

Cytochrome c-type protein NrfB

Gene

nrfB

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Plays a role in nitrite reduction.By similarity

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei65 – 651Heme 1 (covalent)By similarity
    Binding sitei68 – 681Heme 1 (covalent)By similarity
    Metal bindingi69 – 691Iron (heme 1 axial ligand)By similarity
    Binding sitei110 – 1101Heme 2 (covalent)By similarity
    Binding sitei113 – 1131Heme 2 (covalent)By similarity
    Metal bindingi114 – 1141Iron (heme 2 axial ligand)By similarity
    Binding sitei152 – 1521Heme 3 (covalent)By similarity
    Binding sitei155 – 1551Heme 3 (covalent)By similarity
    Metal bindingi156 – 1561Iron (heme 3 axial ligand)By similarity
    Binding sitei177 – 1771Heme 4 (covalent)By similarity
    Binding sitei180 – 1801Heme 4 (covalent)By similarity
    Metal bindingi181 – 1811Iron (heme 4 axial ligand)By similarity
    Binding sitei202 – 2021Heme 5 (covalent)By similarity
    Binding sitei205 – 2051Heme 5 (covalent)By similarity
    Metal bindingi206 – 2061Iron (heme 5 axial ligand)By similarity

    GO - Molecular functioni

    1. heme binding Source: InterPro
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. nitrogen compound metabolic process Source: UniProtKB-UniPathway
    2. oxidation-reduction process Source: UniProtKB-KW

    Keywords - Biological processi

    Electron transport, Transport

    Keywords - Ligandi

    Heme, Iron, Metal-binding

    Enzyme and pathway databases

    UniPathwayiUPA00045.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c-type protein NrfB
    Gene namesi
    Name:nrfB
    Ordered Locus Names:HI_1068
    OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
    Taxonomic identifieri71421 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000000579: Chromosome

    Subcellular locationi

    Periplasm Curated

    GO - Cellular componenti

    1. periplasmic space Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Periplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 3939Sequence AnalysisAdd
    BLAST
    Chaini40 – 226187Cytochrome c-type protein NrfBPRO_0000006586Add
    BLAST

    Post-translational modificationi

    Binds 5 heme groups per subunit.By similarity

    Interactioni

    Protein-protein interaction databases

    STRINGi71421.HI1068.

    Structurei

    3D structure databases

    ProteinModelPortaliP45016.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG06663.
    KOiK04013.
    OMAiQEQNQVC.
    OrthoDBiEOG62ZHTD.

    Family and domain databases

    InterProiIPR017564. Cyt_c_NO2Rdtase_pentahaem-su.
    IPR011031. Multihaem_cyt.
    [Graphical view]
    TIGRFAMsiTIGR03146. cyt_nit_nrfB. 1 hit.
    PROSITEiPS51008. MULTIHEME_CYTC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P45016-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIFKVKFEVT QMILTSLINK SAKALVIVAF VAAPFLAHAD DAQKPAVHVT    50
    YEPQLDNQRD PNQYCAKCHK FDKIDKNQTL DQSGGELHFG KFHGAHLDKK 100
    NPNNGKAITC VSCHGNISEN HRRGAKDVMR FEGDIFGNKK PMYSVQEQNQ 150
    VCFACHQPDK LREKLWAHDV HAMKLPCASC HTLHPKEDAM KGIQPKQRVK 200
    LCVDCHGEQQ KRKAEQDKLI EQKDKL 226
    Length:226
    Mass (Da):25,664
    Last modified:November 1, 1995 - v1
    Checksum:i959F2DCEA668030A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22726.1.
    PIRiB64181.
    RefSeqiNP_439226.2. NC_000907.1.

    Genome annotation databases

    EnsemblBacteriaiAAC22726; AAC22726; HI_1068.
    GeneIDi950046.
    KEGGihin:HI1068.
    PATRICi20190799. VBIHaeInf48452_1112.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22726.1 .
    PIRi B64181.
    RefSeqi NP_439226.2. NC_000907.1.

    3D structure databases

    ProteinModelPortali P45016.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 71421.HI1068.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC22726 ; AAC22726 ; HI_1068 .
    GeneIDi 950046.
    KEGGi hin:HI1068.
    PATRICi 20190799. VBIHaeInf48452_1112.

    Phylogenomic databases

    eggNOGi NOG06663.
    KOi K04013.
    OMAi QEQNQVC.
    OrthoDBi EOG62ZHTD.

    Enzyme and pathway databases

    UniPathwayi UPA00045 .

    Family and domain databases

    InterProi IPR017564. Cyt_c_NO2Rdtase_pentahaem-su.
    IPR011031. Multihaem_cyt.
    [Graphical view ]
    TIGRFAMsi TIGR03146. cyt_nit_nrfB. 1 hit.
    PROSITEi PS51008. MULTIHEME_CYTC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

    Entry informationi

    Entry nameiNRFB_HAEIN
    AccessioniPrimary (citable) accession number: P45016
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 92 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Haemophilus influenzae
      Haemophilus influenzae (strain Rd): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways

    External Data

    Dasty 3