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P45016 (NRFB_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c-type protein NrfB
Gene names
Name:nrfB
Ordered Locus Names:HI_1068
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length226 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Plays a role in nitrite reduction By similarity.

Pathway

Energy metabolism; nitrogen metabolism.

Subcellular location

Periplasm Potential.

Post-translational modification

Binds 5 heme groups per subunit By similarity.

Ontologies

Keywords
   Biological processElectron transport
Transport
   Cellular componentPeriplasm
   DomainSignal
   LigandHeme
Iron
Metal-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processnitrogen compound metabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

oxidation-reduction process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentperiplasmic space

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionheme binding

Inferred from electronic annotation. Source: InterPro

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3939 Potential
Chain40 – 226187Cytochrome c-type protein NrfB
PRO_0000006586

Sites

Metal binding691Iron (heme 1 axial ligand) By similarity
Metal binding1141Iron (heme 2 axial ligand) By similarity
Metal binding1561Iron (heme 3 axial ligand) By similarity
Metal binding1811Iron (heme 4 axial ligand) By similarity
Metal binding2061Iron (heme 5 axial ligand) By similarity
Binding site651Heme 1 (covalent) By similarity
Binding site681Heme 1 (covalent) By similarity
Binding site1101Heme 2 (covalent) By similarity
Binding site1131Heme 2 (covalent) By similarity
Binding site1521Heme 3 (covalent) By similarity
Binding site1551Heme 3 (covalent) By similarity
Binding site1771Heme 4 (covalent) By similarity
Binding site1801Heme 4 (covalent) By similarity
Binding site2021Heme 5 (covalent) By similarity
Binding site2051Heme 5 (covalent) By similarity

Sequences

Sequence LengthMass (Da)Tools
P45016 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 959F2DCEA668030A

FASTA22625,664
        10         20         30         40         50         60 
MIFKVKFEVT QMILTSLINK SAKALVIVAF VAAPFLAHAD DAQKPAVHVT YEPQLDNQRD 

        70         80         90        100        110        120 
PNQYCAKCHK FDKIDKNQTL DQSGGELHFG KFHGAHLDKK NPNNGKAITC VSCHGNISEN 

       130        140        150        160        170        180 
HRRGAKDVMR FEGDIFGNKK PMYSVQEQNQ VCFACHQPDK LREKLWAHDV HAMKLPCASC 

       190        200        210        220 
HTLHPKEDAM KGIQPKQRVK LCVDCHGEQQ KRKAEQDKLI EQKDKL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L42023 Genomic DNA. Translation: AAC22726.1.
PIRB64181.
RefSeqNP_439226.2. NC_000907.1.

3D structure databases

ProteinModelPortalP45016.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING71421.HI1068.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC22726; AAC22726; HI_1068.
GeneID950046.
KEGGhin:HI1068.
PATRIC20190799. VBIHaeInf48452_1112.

Phylogenomic databases

eggNOGNOG06663.
KOK04013.
OMAQEQNQVC.
OrthoDBEOG62ZHTD.

Enzyme and pathway databases

UniPathwayUPA00045.

Family and domain databases

InterProIPR017564. Cyt_c_NO2Rdtase_pentahaem-su.
IPR011031. Multihaem_cyt.
[Graphical view]
TIGRFAMsTIGR03146. cyt_nit_nrfB. 1 hit.
PROSITEPS51008. MULTIHEME_CYTC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNRFB_HAEIN
AccessionPrimary (citable) accession number: P45016
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 14, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names