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P45015 (NRFC_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified December 11, 2013. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein NrfC homolog
Gene names
Name:nrfC
Ordered Locus Names:HI_1067
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length225 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes By similarity.

Post-translational modification

Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

Sequence similarities

Contains 3 4Fe-4S ferredoxin-type domains.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2828Tat-type signal Potential
Chain29 – 225197Protein NrfC homolog
PRO_0000008846

Regions

Domain39 – 67294Fe-4S ferredoxin-type 1
Domain85 – 116324Fe-4S ferredoxin-type 2
Domain118 – 147304Fe-4S ferredoxin-type 3

Sites

Metal binding481Iron-sulfur 1 (4Fe-4S) By similarity
Metal binding511Iron-sulfur 1 (4Fe-4S) By similarity
Metal binding541Iron-sulfur 1 (4Fe-4S) By similarity
Metal binding581Iron-sulfur 2 (4Fe-4S) By similarity
Metal binding941Iron-sulfur 3 (4Fe-4S) By similarity
Metal binding971Iron-sulfur 3 (4Fe-4S) By similarity
Metal binding1021Iron-sulfur 3 (4Fe-4S) By similarity
Metal binding1061Iron-sulfur 4 (4Fe-4S) By similarity
Metal binding1271Iron-sulfur 4 (4Fe-4S) By similarity
Metal binding1301Iron-sulfur 4 (4Fe-4S) By similarity
Metal binding1331Iron-sulfur 4 (4Fe-4S) By similarity
Metal binding1371Iron-sulfur 3 (4Fe-4S) By similarity
Metal binding1541Iron-sulfur 2 (4Fe-4S) By similarity
Metal binding1571Iron-sulfur 2 (4Fe-4S) By similarity
Metal binding1701Iron-sulfur 2 (4Fe-4S) By similarity
Metal binding1741Iron-sulfur 1 (4Fe-4S) By similarity

Sequences

Sequence LengthMass (Da)Tools
P45015 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: F2E28CA9C9471CAB

FASTA22525,105
        10         20         30         40         50         60 
MTVCSRRNFV SGMGAVILMT GTSLPAFAKE NKADKPKRYA MIHDENACIG CTACMDSCRD 

        70         80         90        100        110        120 
VNQVPEGVSR LEILRSEPYG EFPNQEYEFF RQSCQHCTNA PCVAVCPTGA SFIDKETGIV 

       130        140        150        160        170        180 
DVHKDLCIGC QYCIAVCPYR VRFIHPIHRT ADKCNFCRDT NLANGKQPAC VEACPTKALT 

       190        200        210        220 
FGDMNDPTSA VSRKVKEKPV YRTKVELGTQ PNLYHIPFQH GEPRR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L42023 Genomic DNA. Translation: AAC22725.1.
PIRA64181.
RefSeqNP_439225.1. NC_000907.1.

3D structure databases

ProteinModelPortalP45015.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING71421.HI1067.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC22725; AAC22725; HI_1067.
GeneID950045.
KEGGhin:HI1067.
PATRIC20190797. VBIHaeInf48452_1111.

Phylogenomic databases

eggNOGCOG0437.
KOK04014.
OMARFIHPVH.
OrthoDBEOG6JTC8Q.
ProtClustDBCLSK869937.

Family and domain databases

InterProIPR001450. 4Fe4S-bd_dom.
IPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR017567. Cyt_c_NO2Rdtase_NrfC.
IPR006311. TAT_signal.
[Graphical view]
PfamPF00037. Fer4. 1 hit.
PF12798. Fer4_3. 1 hit.
PF12838. Fer4_7. 1 hit.
[Graphical view]
TIGRFAMsTIGR03149. cyt_nit_nrfC. 1 hit.
PROSITEPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 3 hits.
PS51318. TAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNRFC_HAEIN
AccessionPrimary (citable) accession number: P45015
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: December 11, 2013
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names