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P45015

- NRFC_HAEIN

UniProt

P45015 - NRFC_HAEIN

Protein

Protein NrfC homolog

Gene

nrfC

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 100 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi48 – 481Iron-sulfur 1 (4Fe-4S)By similarity
    Metal bindingi51 – 511Iron-sulfur 1 (4Fe-4S)By similarity
    Metal bindingi54 – 541Iron-sulfur 1 (4Fe-4S)By similarity
    Metal bindingi58 – 581Iron-sulfur 2 (4Fe-4S)By similarity
    Metal bindingi94 – 941Iron-sulfur 3 (4Fe-4S)By similarity
    Metal bindingi97 – 971Iron-sulfur 3 (4Fe-4S)By similarity
    Metal bindingi102 – 1021Iron-sulfur 3 (4Fe-4S)By similarity
    Metal bindingi106 – 1061Iron-sulfur 4 (4Fe-4S)By similarity
    Metal bindingi127 – 1271Iron-sulfur 4 (4Fe-4S)By similarity
    Metal bindingi130 – 1301Iron-sulfur 4 (4Fe-4S)By similarity
    Metal bindingi133 – 1331Iron-sulfur 4 (4Fe-4S)By similarity
    Metal bindingi137 – 1371Iron-sulfur 3 (4Fe-4S)By similarity
    Metal bindingi154 – 1541Iron-sulfur 2 (4Fe-4S)By similarity
    Metal bindingi157 – 1571Iron-sulfur 2 (4Fe-4S)By similarity
    Metal bindingi170 – 1701Iron-sulfur 2 (4Fe-4S)By similarity
    Metal bindingi174 – 1741Iron-sulfur 1 (4Fe-4S)By similarity

    GO - Molecular functioni

    1. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW
    3. oxidoreductase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Electron transport, Transport

    Keywords - Ligandi

    4Fe-4S, Iron, Iron-sulfur, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein NrfC homolog
    Gene namesi
    Name:nrfC
    Ordered Locus Names:HI_1067
    OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
    Taxonomic identifieri71421 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000000579: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2828Tat-type signalPROSITE-ProRule annotationAdd
    BLAST
    Chaini29 – 225197Protein NrfC homologPRO_0000008846Add
    BLAST

    Post-translational modificationi

    Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

    Interactioni

    Protein-protein interaction databases

    STRINGi71421.HI1067.

    Structurei

    3D structure databases

    ProteinModelPortaliP45015.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini39 – 67294Fe-4S ferredoxin-type 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini85 – 116324Fe-4S ferredoxin-type 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini118 – 147304Fe-4S ferredoxin-type 3PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 3 4Fe-4S ferredoxin-type domains.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, Signal

    Phylogenomic databases

    eggNOGiCOG0437.
    KOiK04014.
    OMAiIEREGPF.
    OrthoDBiEOG6JTC8Q.
    PhylomeDBiP45015.

    Family and domain databases

    InterProiIPR001450. 4Fe4S-bd_dom.
    IPR017896. 4Fe4S_Fe-S-bd.
    IPR017900. 4Fe4S_Fe_S_CS.
    IPR017567. Cyt_c_NO2Rdtase_NrfC.
    IPR006311. TAT_signal.
    [Graphical view]
    PfamiPF00037. Fer4. 1 hit.
    PF12798. Fer4_3. 1 hit.
    PF12838. Fer4_7. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR03149. cyt_nit_nrfC. 1 hit.
    PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
    PS51379. 4FE4S_FER_2. 3 hits.
    PS51318. TAT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P45015-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTVCSRRNFV SGMGAVILMT GTSLPAFAKE NKADKPKRYA MIHDENACIG    50
    CTACMDSCRD VNQVPEGVSR LEILRSEPYG EFPNQEYEFF RQSCQHCTNA 100
    PCVAVCPTGA SFIDKETGIV DVHKDLCIGC QYCIAVCPYR VRFIHPIHRT 150
    ADKCNFCRDT NLANGKQPAC VEACPTKALT FGDMNDPTSA VSRKVKEKPV 200
    YRTKVELGTQ PNLYHIPFQH GEPRR 225
    Length:225
    Mass (Da):25,105
    Last modified:November 1, 1995 - v1
    Checksum:iF2E28CA9C9471CAB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22725.1.
    PIRiA64181.
    RefSeqiNP_439225.1. NC_000907.1.

    Genome annotation databases

    EnsemblBacteriaiAAC22725; AAC22725; HI_1067.
    GeneIDi950045.
    KEGGihin:HI1067.
    PATRICi20190797. VBIHaeInf48452_1111.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22725.1 .
    PIRi A64181.
    RefSeqi NP_439225.1. NC_000907.1.

    3D structure databases

    ProteinModelPortali P45015.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 71421.HI1067.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC22725 ; AAC22725 ; HI_1067 .
    GeneIDi 950045.
    KEGGi hin:HI1067.
    PATRICi 20190797. VBIHaeInf48452_1111.

    Phylogenomic databases

    eggNOGi COG0437.
    KOi K04014.
    OMAi IEREGPF.
    OrthoDBi EOG6JTC8Q.
    PhylomeDBi P45015.

    Family and domain databases

    InterProi IPR001450. 4Fe4S-bd_dom.
    IPR017896. 4Fe4S_Fe-S-bd.
    IPR017900. 4Fe4S_Fe_S_CS.
    IPR017567. Cyt_c_NO2Rdtase_NrfC.
    IPR006311. TAT_signal.
    [Graphical view ]
    Pfami PF00037. Fer4. 1 hit.
    PF12798. Fer4_3. 1 hit.
    PF12838. Fer4_7. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR03149. cyt_nit_nrfC. 1 hit.
    PROSITEi PS00198. 4FE4S_FER_1. 1 hit.
    PS51379. 4FE4S_FER_2. 3 hits.
    PS51318. TAT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

    Entry informationi

    Entry nameiNRFC_HAEIN
    AccessioniPrimary (citable) accession number: P45015
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 100 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Haemophilus influenzae
      Haemophilus influenzae (strain Rd): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3