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Protein

Protein NrfC homolog

Gene

nrfC

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi48Iron-sulfur 1 (4Fe-4S)By similarity1
Metal bindingi51Iron-sulfur 1 (4Fe-4S)By similarity1
Metal bindingi54Iron-sulfur 1 (4Fe-4S)By similarity1
Metal bindingi58Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi94Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi97Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi102Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi106Iron-sulfur 4 (4Fe-4S)By similarity1
Metal bindingi127Iron-sulfur 4 (4Fe-4S)By similarity1
Metal bindingi130Iron-sulfur 4 (4Fe-4S)By similarity1
Metal bindingi133Iron-sulfur 4 (4Fe-4S)By similarity1
Metal bindingi137Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi154Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi157Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi170Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi174Iron-sulfur 1 (4Fe-4S)By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
Biological processElectron transport, Transport
Ligand4Fe-4S, Iron, Iron-sulfur, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein NrfC homolog
Gene namesi
Name:nrfC
Ordered Locus Names:HI_1067
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000000579 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Tat-type signalPROSITE-ProRule annotationAdd BLAST28
ChainiPRO_000000884629 – 225Protein NrfC homologAdd BLAST197

Post-translational modificationi

Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

Interactioni

Protein-protein interaction databases

STRINGi71421.HI1067.

Structurei

3D structure databases

ProteinModelPortaliP45015.
SMRiP45015.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 674Fe-4S ferredoxin-type 1PROSITE-ProRule annotationAdd BLAST29
Domaini85 – 1164Fe-4S ferredoxin-type 2PROSITE-ProRule annotationAdd BLAST32
Domaini118 – 1474Fe-4S ferredoxin-type 3PROSITE-ProRule annotationAdd BLAST30

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiENOG4105D3S. Bacteria.
COG0437. LUCA.
KOiK04014.
OMAiCMHCENT.
PhylomeDBiP45015.

Family and domain databases

InterProiView protein in InterPro
IPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR017567. Cyt_c_NO2Rdtase_NrfC.
IPR006311. TAT_signal.
PfamiView protein in Pfam
PF13247. Fer4_11. 1 hit.
TIGRFAMsiTIGR03149. cyt_nit_nrfC. 1 hit.
PROSITEiView protein in PROSITE
PS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 3 hits.
PS51318. TAT. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P45015-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVCSRRNFV SGMGAVILMT GTSLPAFAKE NKADKPKRYA MIHDENACIG
60 70 80 90 100
CTACMDSCRD VNQVPEGVSR LEILRSEPYG EFPNQEYEFF RQSCQHCTNA
110 120 130 140 150
PCVAVCPTGA SFIDKETGIV DVHKDLCIGC QYCIAVCPYR VRFIHPIHRT
160 170 180 190 200
ADKCNFCRDT NLANGKQPAC VEACPTKALT FGDMNDPTSA VSRKVKEKPV
210 220
YRTKVELGTQ PNLYHIPFQH GEPRR
Length:225
Mass (Da):25,105
Last modified:November 1, 1995 - v1
Checksum:iF2E28CA9C9471CAB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22725.1.
PIRiA64181.
RefSeqiNP_439225.1. NC_000907.1.
WP_005647733.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22725; AAC22725; HI_1067.
GeneIDi950045.
KEGGihin:HI1067.
PATRICifig|71421.8.peg.1111.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiNRFC_HAEIN
AccessioniPrimary (citable) accession number: P45015
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: June 7, 2017
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names