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P44999 (T2D5_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable type-2 restriction enzyme HindVP

Short name=R.HindVP
EC=3.1.21.4
Alternative name(s):
Endonuclease HindVP
Type II restriction enzyme HindVP
Gene names
Name:hindVRP
Ordered Locus Names:HI_1040
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length334 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Catalytic activity

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

Ontologies

Keywords
   Biological processRestriction system
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processDNA restriction-modification system

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: InterPro

Type II site-specific deoxyribonuclease activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 334334Probable type-2 restriction enzyme HindVP
PRO_0000077322

Sequences

Sequence LengthMass (Da)Tools
P44999 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 8CA1F88E76E730DD

FASTA33438,346
        10         20         30         40         50         60 
MLYYVPRREK SYMNIKPHLF GLNRSNRDFS LRETWGKNQF NSSFPVSLCC YMSSKGILAN 

        70         80         90        100        110        120 
YLSIENAEIK CSSIDIKDVF EIEPENENTF FAFETSHSIK LTALPDHTTC DLTDADFGSE 

       130        140        150        160        170        180 
IVIRPDSIVY LACSLAEILK ESLANCMDIP NNVDHLDWSE PKQVIPLFPH ILSTLNNLCS 

       190        200        210        220        230        240 
RADTIQTPFL LQPVWKTLGK SPRLADNCLD IFIWSDVAFV KFILEISNLN VNVLSINRQT 

       250        260        270        280        290        300 
RTAIWLYKML VDIVKYGRFN HHKIIDLCSY NTKNDKAFAS SGMITNVFMK SERLERPIIM 

       310        320        330 
KSEIKNIILG GGQELLSPER RFDAIIYNSS ELFR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L42023 Genomic DNA. Translation: AAC22699.1.
PIRB64109.
RefSeqNP_439199.1. NC_000907.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING71421.HI1040.

Protein family/group databases

REBASE2819. HindVP.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC22699; AAC22699; HI_1040.
GeneID950604.
KEGGhin:HI1040.
PATRIC20190743. VBIHaeInf48452_1084.

Phylogenomic databases

eggNOGNOG256210.
KOK01155.
OMATKNDKAF.
OrthoDBEOG6677SG.

Family and domain databases

InterProIPR019044. Restrct_endonuc_II_HindVP.
[Graphical view]
PfamPF09519. RE_HindVP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameT2D5_HAEIN
AccessionPrimary (citable) accession number: P44999
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 14, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Restriction enzymes and methylases

Classification of restriction enzymes and methylases and list of entries

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names