Reviewed, UniProtKB/Swiss-Prot P44999 (T2D5_HAEIN)

Names and origin

Protein names

Recommended name:
    Probable type-2 restriction enzyme HindVP
      Short name=R.HindVP
    EC=3.1.21.4
Alternative name(s):
    Type II restriction enzyme HindVP
    Endonuclease HindVP

Gene names

Name:	hindVRP
Ordered Locus Names:	HI1040

Organism

Haemophilus influenzae [Complete proteome] [HAMAP]

Taxonomic identifier

727 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	334 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Predicted.

General annotation (Comments)

Catalytic activity

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

Ontologies

Keywords
Biological process	Restriction system
Molecular function	Endonuclease Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA restriction-modification system Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro Type II site-specific deoxyribonuclease activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 334	334	Probable type-2 restriction enzyme HindVP		PRO_0000077322

Sequences

	Sequence		Length	Mass (Da)
	P44999-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 8CA1F88E76E730DD	FASTA	334	38,346
	10 20 30 40 50 60 MLYYVPRREK SYMNIKPHLF GLNRSNRDFS LRETWGKNQF NSSFPVSLCC YMSSKGILAN 70 80 90 100 110 120 YLSIENAEIK CSSIDIKDVF EIEPENENTF FAFETSHSIK LTALPDHTTC DLTDADFGSE 130 140 150 160 170 180 IVIRPDSIVY LACSLAEILK ESLANCMDIP NNVDHLDWSE PKQVIPLFPH ILSTLNNLCS 190 200 210 220 230 240 RADTIQTPFL LQPVWKTLGK SPRLADNCLD IFIWSDVAFV KFILEISNLN VNVLSINRQT 250 260 270 280 290 300 RTAIWLYKML VDIVKYGRFN HHKIIDLCSY NTKNDKAFAS SGMITNVFMK SERLERPIIM 310 320 330 KSEIKNIILG GGQELLSPER RFDAIIYNSS ELFR

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L42023 Genomic DNA. Translation: AAC22699.1.
PIR	B64109.
RefSeq	NP_439199.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	950604.
GenomeReviews	Gene locus HI1040 in contig L42023_GR.
KEGG	hin:HI1040.
NMPDR	fig|71421.1.peg.1001.
TIGR	HI1040.
Phylogenomic databases
OMA	NTKNDKA.
Enzyme and pathway databases
BioCyc	HINF71421:HI_1040-MON.
BRENDA	3.1.21.4. 109.
Family and domain databases
InterPro	IPR019044. Restrict_endonuc_II_HindVP. [Graphical view]
Pfam	PF09519. RE_HindVP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

T2D5_HAEIN

Accession

Primary (citable) accession number: P44999

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	November 3, 2009
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)