Reviewed, UniProtKB/Swiss-Prot P44997 (SERB_HAEIN)

Names and origin

Protein names

Recommended name:
    Phosphoserine phosphatase
      Short name=PSPase
      Short name=PSP
    EC=3.1.3.3
Alternative name(s):
    O-phosphoserine phosphohydrolase

Gene names

Name:	serB
Ordered Locus Names:	HI1033

Organism

Haemophilus influenzae [Complete proteome] [HAMAP]

Taxonomic identifier

727 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	314 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	O-phospho-L(or D)-serine + H2O = L(or D)-serine + phosphate.
Pathway	Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 3/3.
Sequence similarities	Belongs to the serB family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Serine biosynthesis
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	L-serine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	phosphoserine phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 314	314	Phosphoserine phosphatase		PRO_0000156888

Sequences

	Sequence		Length	Mass (Da)
	P44997-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: ED565F9C78CE0FB1	FASTA	314	34,720
	10 20 30 40 50 60 MQIQCFESIT QKYPQFPTAL LANEEPIQNG EPFILYGTKL DITKLEKFQQ KCGQNFQIFD 70 80 90 100 110 120 VWMVAKNIIV LLKGQWFSDF IKFTHDVEVD IAKLDFSPKL SQAGLLVMDM DSTAIQIECI 130 140 150 160 170 180 DEIAKLAGVG ELVSAITESA MRGELDFEQS LRCRVGTLKG APESILQQVR ENLPLMSGLV 190 200 210 220 230 240 ETIQTLQKYG WKTAIASGGF TYFADYLKAL LQLDFAASNQ FDIEDGKLTG LVKGDVVDAQ 250 260 270 280 290 300 YKAKTLQHLL EEYGIDSRHS IAIGDGANDL AMMNVAGLGV AFHAKPKVQP QAQIVVNFAD 310 LTALLCLLSA NDRI

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC22693.1.
PIR	I64108.
RefSeq	NP_439193.1.
3D structure databases
SMR	P44997. Positions 104-308.
ModBase	Search...
Genome annotation databases
GeneID	949401.
GenomeReviews	Gene locus HI1033 in contig L42023_GR.
KEGG	hin:HI1033.
NMPDR	fig|71421.1.peg.995.
TIGR	HI1033.
Phylogenomic databases
HOGENOM	HBG645339.
OMA	AQSNQLE.
Enzyme and pathway databases
BioCyc	HINF71421:HI_1033-MONOMER.
BRENDA	3.1.3.3. 109.
Family and domain databases
InterPro	IPR005834. Dehalogen-like_hydro. IPR006383. HAD-SF_hydro_IB_PSP-like. IPR004469. SerB. [Graphical view]
Pfam	PF00702. Hydrolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01488. HAD-SF-IB. 1 hit. TIGR00338. serB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SERB_HAEIN

Accession

Primary (citable) accession number: P44997

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	February 9, 2010
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)