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Protein

Probable L-xylulose kinase

Gene

lyx

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-xylulose = ADP + L-xylulose 5-phosphate.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable L-xylulose kinase (EC:2.7.1.53)
Short name:
L-xylulokinase
Gene namesi
Name:lyx
Synonyms:lyxK, sgbK
Ordered Locus Names:HI_1027
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 485485Probable L-xylulose kinasePRO_0000059561Add
BLAST

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi71421.HI1027.

Structurei

3D structure databases

ProteinModelPortaliP44991.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FGGY kinase family.Curated

Phylogenomic databases

eggNOGiCOG1070.
KOiK00880.
OMAiFMSSTFD.
OrthoDBiEOG6KDKMT.
PhylomeDBiP44991.

Family and domain databases

InterProiIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
[Graphical view]
PfamiPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000538. GlpK. 1 hit.
PROSITEiPS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P44991-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHYYLGIDCG GTFIKAAIFD QNGTLQSIAR RNIPIISEKP GYAERDMDEL
60 70 80 90 100
WNLCAQVIQK TIRQSSILPQ QIKAIGISAQ GKGAFFLDKD NKPLGRAILS
110 120 130 140 150
SDQRAYEIVQ CWQKENILQK FYPITLQTLW MGHPVSILRW IKENEPSRYE
160 170 180 190 200
QIHTILMSHD YLRFCLTEKL YCEETNISES NFYNMREGKY DIQLAKLFGI
210 220 230 240 250
TECIDKLPPI IKSNKIAGYV TSRAAEQSGL VEGIPVVGGL FDVVSTALCA
260 270 280 290 300
DLKDDQHLNV VLGTWSVVSG VTHYIDDNQT IPFVYGKYPE KNKFIIHEAS
310 320 330 340 350
PTSAGNLEWF VNQFNLPNYD DINHEIAKLK PASSSVLFAP FLYGSNAKLG
360 370 380 390 400
MQAGFYGIQS HHTQIHLLQA IYEGVIFSLM SHLERMQVRF PNASTVRVTG
410 420 430 440 450
GPAKSEVWMQ MLADISGMRL EIPNIEETGC LGAALMAMQA ESAVEISQIL
460 470 480
NIDRKIFLPD KNQYSKYQHK YHRYLKFIEA LKNLD
Length:485
Mass (Da):54,965
Last modified:November 1, 1995 - v1
Checksum:i8E63C56CB775A66D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22687.1.
PIRiH64164.
RefSeqiNP_439187.1. NC_000907.1.
WP_010869108.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22687; AAC22687; HI_1027.
GeneIDi949892.
KEGGihin:HI1027.
PATRICi20190717. VBIHaeInf48452_1071.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22687.1.
PIRiH64164.
RefSeqiNP_439187.1. NC_000907.1.
WP_010869108.1. NC_000907.1.

3D structure databases

ProteinModelPortaliP44991.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi71421.HI1027.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC22687; AAC22687; HI_1027.
GeneIDi949892.
KEGGihin:HI1027.
PATRICi20190717. VBIHaeInf48452_1071.

Phylogenomic databases

eggNOGiCOG1070.
KOiK00880.
OMAiFMSSTFD.
OrthoDBiEOG6KDKMT.
PhylomeDBiP44991.

Family and domain databases

InterProiIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
[Graphical view]
PfamiPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000538. GlpK. 1 hit.
PROSITEiPS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiLYXK_HAEIN
AccessioniPrimary (citable) accession number: P44991
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 27, 2015
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.