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P44957

- RIBF_HAEIN

UniProt

P44957 - RIBF_HAEIN

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Protein
Riboflavin biosynthesis protein RibF
Gene
ribF, HI_0963
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + riboflavin = ADP + FMN.
ATP + FMN = diphosphate + FAD.

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. FMN adenylyltransferase activity Source: UniProtKB-EC
  3. riboflavin kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. FAD biosynthetic process Source: UniProtKB-UniPathway
  2. FMN biosynthetic process Source: UniProtKB-UniPathway
  3. riboflavin biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Nucleotidyltransferase, Transferase

Keywords - Ligandi

ATP-binding, FAD, Flavoprotein, FMN, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00276; UER00406.
UPA00277; UER00407.

Names & Taxonomyi

Protein namesi
Recommended name:
Riboflavin biosynthesis protein RibF
Including the following 2 domains:
Riboflavin kinase (EC:2.7.1.26)
Alternative name(s):
Flavokinase
FMN adenylyltransferase (EC:2.7.7.2)
Alternative name(s):
FAD pyrophosphorylase
FAD synthase
Gene namesi
Name:ribF
Ordered Locus Names:HI_0963
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 308308Riboflavin biosynthesis protein RibF
PRO_0000194140Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0963.

Structurei

3D structure databases

ProteinModelPortaliP44957.

Family & Domainsi

Sequence similaritiesi

Belongs to the RibF family.

Phylogenomic databases

eggNOGiCOG0196.
KOiK11753.
OMAiPQFDGTE.
OrthoDBiEOG6QP0ZV.

Family and domain databases

Gene3Di2.40.30.30. 1 hit.
3.40.50.620. 1 hit.
InterProiIPR004821. Cyt_trans-like.
IPR015864. FAD_synthase.
IPR023468. Riboflavin_kinase.
IPR002606. Riboflavin_kinase_bac.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR22749. PTHR22749. 1 hit.
PfamiPF06574. FAD_syn. 1 hit.
PF01687. Flavokinase. 1 hit.
[Graphical view]
PIRSFiPIRSF004491. FAD_Synth. 1 hit.
SMARTiSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMiSSF82114. SSF82114. 1 hit.
TIGRFAMsiTIGR00125. cyt_tran_rel. 1 hit.
TIGR00083. ribF. 1 hit.

Sequencei

Sequence statusi: Complete.

P44957-1 [UniParc]FASTAAdd to Basket

« Hide

MQLIRGLHNA NRVLQGCALT IGNFDGVHLG HQTVLRHLRQ KADELNLPMA    50
VLLFESQPRE YFMGKNAPAR LMRLRDKIYY LEKAKVDVVI VAKFDRTFAE 100
QLADVFIEQT LVNHLHVKFL SIGDDFKFGS KRQGNFAMLQ AASKRFGFIV 150
EDNRSFCLDA QRISSTAIRE ALANDDLQLA ENLLGKPYRI FGRVIHGNKL 200
GRTIGFPTAN IRLHRQVNPI KGVYAVKVRL KSGEIFNGVA NMGKRPTING 250
LMQLLEVHLF DFSQNIYGQM VEVEFCHKIR NEIKFPSFDD LKVQIEKDVE 300
TAKAFFNS 308
Length:308
Mass (Da):35,121
Last modified:November 1, 1995 - v1
Checksum:i5DA4EA0F5492923E
GO

Sequence cautioni

The sequence AAC22622.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC22622.1. Different initiation.
PIRiH64162.
RefSeqiNP_439124.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22622; AAC22622; HI_0963.
GeneIDi949965.
KEGGihin:HI0963.
PATRICi20190585. VBIHaeInf48452_1005.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC22622.1 . Different initiation.
PIRi H64162.
RefSeqi NP_439124.1. NC_000907.1.

3D structure databases

ProteinModelPortali P44957.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 71421.HI0963.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC22622 ; AAC22622 ; HI_0963 .
GeneIDi 949965.
KEGGi hin:HI0963.
PATRICi 20190585. VBIHaeInf48452_1005.

Phylogenomic databases

eggNOGi COG0196.
KOi K11753.
OMAi PQFDGTE.
OrthoDBi EOG6QP0ZV.

Enzyme and pathway databases

UniPathwayi UPA00276 ; UER00406 .
UPA00277 ; UER00407 .

Family and domain databases

Gene3Di 2.40.30.30. 1 hit.
3.40.50.620. 1 hit.
InterProi IPR004821. Cyt_trans-like.
IPR015864. FAD_synthase.
IPR023468. Riboflavin_kinase.
IPR002606. Riboflavin_kinase_bac.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
PANTHERi PTHR22749. PTHR22749. 1 hit.
Pfami PF06574. FAD_syn. 1 hit.
PF01687. Flavokinase. 1 hit.
[Graphical view ]
PIRSFi PIRSF004491. FAD_Synth. 1 hit.
SMARTi SM00904. Flavokinase. 1 hit.
[Graphical view ]
SUPFAMi SSF82114. SSF82114. 1 hit.
TIGRFAMsi TIGR00125. cyt_tran_rel. 1 hit.
TIGR00083. ribF. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiRIBF_HAEIN
AccessioniPrimary (citable) accession number: P44957
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 14, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Multifunctional enzyme, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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