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P44957 (RIBF_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Riboflavin biosynthesis protein RibF

Including the following 2 domains:

  1. Riboflavin kinase
    EC=2.7.1.26
    Alternative name(s):
    Flavokinase
  2. FMN adenylyltransferase
    EC=2.7.7.2
    Alternative name(s):
    FAD pyrophosphorylase
    FAD synthase
Gene names
Name:ribF
Ordered Locus Names:HI_0963
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length308 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + riboflavin = ADP + FMN.

ATP + FMN = diphosphate + FAD.

Pathway

Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.

Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.

Sequence similarities

Belongs to the RibF family.

Sequence caution

The sequence AAC22622.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 308308Riboflavin biosynthesis protein RibF
PRO_0000194140

Sequences

Sequence LengthMass (Da)Tools
P44957 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 5DA4EA0F5492923E

FASTA30835,121
        10         20         30         40         50         60 
MQLIRGLHNA NRVLQGCALT IGNFDGVHLG HQTVLRHLRQ KADELNLPMA VLLFESQPRE 

        70         80         90        100        110        120 
YFMGKNAPAR LMRLRDKIYY LEKAKVDVVI VAKFDRTFAE QLADVFIEQT LVNHLHVKFL 

       130        140        150        160        170        180 
SIGDDFKFGS KRQGNFAMLQ AASKRFGFIV EDNRSFCLDA QRISSTAIRE ALANDDLQLA 

       190        200        210        220        230        240 
ENLLGKPYRI FGRVIHGNKL GRTIGFPTAN IRLHRQVNPI KGVYAVKVRL KSGEIFNGVA 

       250        260        270        280        290        300 
NMGKRPTING LMQLLEVHLF DFSQNIYGQM VEVEFCHKIR NEIKFPSFDD LKVQIEKDVE 


TAKAFFNS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L42023 Genomic DNA. Translation: AAC22622.1. Different initiation.
PIRH64162.
RefSeqNP_439124.1. NC_000907.1.

3D structure databases

ProteinModelPortalP44957.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING71421.HI0963.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC22622; AAC22622; HI_0963.
GeneID949965.
KEGGhin:HI0963.
PATRIC20190585. VBIHaeInf48452_1005.

Phylogenomic databases

eggNOGCOG0196.
KOK11753.
OMAPQFDGTE.
OrthoDBEOG6QP0ZV.

Enzyme and pathway databases

UniPathwayUPA00276; UER00406.
UPA00277; UER00407.

Family and domain databases

Gene3D2.40.30.30. 1 hit.
3.40.50.620. 1 hit.
InterProIPR004821. Cyt_trans-like.
IPR015864. FAD_synthase.
IPR023468. Riboflavin_kinase.
IPR002606. Riboflavin_kinase_bac.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR22749. PTHR22749. 1 hit.
PfamPF06574. FAD_syn. 1 hit.
PF01687. Flavokinase. 1 hit.
[Graphical view]
PIRSFPIRSF004491. FAD_Synth. 1 hit.
SMARTSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMSSF82114. SSF82114. 1 hit.
TIGRFAMsTIGR00125. cyt_tran_rel. 1 hit.
TIGR00083. ribF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRIBF_HAEIN
AccessionPrimary (citable) accession number: P44957
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 14, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names