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Protein

Formate-dependent nitrite reductase complex bifunctional subunit NrfFG

Gene

nrfF

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Possible subunit of a heme lyase.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei61Heme (covalent)Sequence analysis1
Binding sitei64Heme (covalent)Sequence analysis1

GO - Molecular functioni

Keywordsi

LigandHeme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciHINF71421:G1GJ1-974-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Formate-dependent nitrite reductase complex bifunctional subunit NrfFG
Gene namesi
Name:nrfF
Ordered Locus Names:HI_0934
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000000579 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 35Sequence analysisAdd BLAST35
ChainiPRO_000000661636 – 384Formate-dependent nitrite reductase complex bifunctional subunit NrfFGAdd BLAST349

Proteomic databases

PRIDEiP44942

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0934

Structurei

3D structure databases

ProteinModelPortaliP44942
SMRiP44942
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati221 – 254TPR 1Add BLAST34
Repeati255 – 288TPR 2Add BLAST34

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni36 – 144NrfFAdd BLAST109
Regioni180 – 384NrfGAdd BLAST205

Sequence similaritiesi

Belongs to the CcmH/CycL/Ccl2/NrfF family.Curated

Keywords - Domaini

Repeat, Signal, TPR repeat

Phylogenomic databases

eggNOGiENOG4108DMF Bacteria
COG3088 LUCA
COG4235 LUCA
KOiK04017
K04018
OMAiQNNEFDS
PhylomeDBiP44942

Family and domain databases

Gene3Di1.10.8.640, 1 hit
1.25.40.10, 2 hits
InterProiView protein in InterPro
IPR005616 CcmH/CycL/Ccl2/NrfF
IPR038297 CcmH/CycL/NrfF/Ccl2_sf
IPR017565 For-dep_Cytc_NO2Rdtase_NrfF
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PfamiView protein in Pfam
PF03918 CcmH, 1 hit
SMARTiView protein in SMART
SM00028 TPR, 1 hit
SUPFAMiSSF48452 SSF48452, 1 hit
TIGRFAMsiTIGR03147 cyt_nit_nrfF, 1 hit
PROSITEiView protein in PROSITE
PS50005 TPR, 1 hit
PS50293 TPR_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P44942-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSILDIFTR GFIQVQKTVF FATALLFAFS LFTQAEMVDT YQFQNQDDRT
60 70 80 90 100
RAVELAKSLR CPQCQNQNLV ESNSPIAYDL RLEVYKMVDE GKSNQQIIDK
110 120 130 140 150
MTARFGDFVN YKPPFKWNTA LLWLLPVALL ILAAVLLYFS NRKKQFSEKV
160 170 180 190 200
VAQQLENDEI ISLPSTFGSS PRKQGEPSKL SKGKVNSKIY FVLFTLLIAI
210 220 230 240 250
PATYYFSLDR FSRVQQGEQS MIEQHNQNVE MNDEHKNENV IEKLQNKLRT
260 270 280 290 300
DPNNAETWLQ LGEAYVQNNE FDSALVAYSN AEKLSGSKPN ILGLAATALY
310 320 330 340 350
YQAGQQMTQK VEQLLNEALA KDKNEVSSLS LLATIALENR QYQQAGMYLQ
360 370 380
QLLDSGNAAV DRRSVIQRMK MLDFLQRGEK GQNP
Length:384
Mass (Da):43,780
Last modified:June 6, 2002 - v2
Checksum:i0321F4A7704964C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA Translation: AAC22592.1
PIRiH64161
RefSeqiNP_439094.1, NC_000907.1
WP_005693281.1, NC_000907.1

Genome annotation databases

EnsemblBacteriaiAAC22592; AAC22592; HI_0934
GeneIDi949938
KEGGihin:HI0934
PATRICifig|71421.8.peg.975

Similar proteinsi

Entry informationi

Entry nameiNRFF_HAEIN
AccessioniPrimary (citable) accession number: P44942
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: June 6, 2002
Last modified: May 23, 2018
This is version 120 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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