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P44942 (NRFF_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Formate-dependent nitrite reductase complex bifunctional subunit NrfFG
Gene names
Name:nrfF
Ordered Locus Names:HI_0934
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length384 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Possible subunit of a heme lyase By similarity.

Subcellular location

Periplasm Probable.

Sequence similarities

Belongs to the CcmH/CycL/Ccl2/NrfF family.

Contains 2 TPR repeats.

Ontologies

Keywords
   Cellular componentPeriplasm
   DomainRepeat
Signal
TPR repeat
   LigandHeme
Iron
Metal-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentperiplasmic space

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3535 Potential
Chain36 – 384349Formate-dependent nitrite reductase complex bifunctional subunit NrfFG
PRO_0000006616

Regions

Repeat221 – 25434TPR 1
Repeat255 – 28834TPR 2
Region36 – 144109NrfF
Region180 – 384205NrfG

Sites

Binding site611Heme (covalent) Potential
Binding site641Heme (covalent) Potential

Sequences

Sequence LengthMass (Da)Tools
P44942 [UniParc].

Last modified June 6, 2002. Version 2.
Checksum: 0321F4A7704964C4

FASTA38443,780
        10         20         30         40         50         60 
MKSILDIFTR GFIQVQKTVF FATALLFAFS LFTQAEMVDT YQFQNQDDRT RAVELAKSLR 

        70         80         90        100        110        120 
CPQCQNQNLV ESNSPIAYDL RLEVYKMVDE GKSNQQIIDK MTARFGDFVN YKPPFKWNTA 

       130        140        150        160        170        180 
LLWLLPVALL ILAAVLLYFS NRKKQFSEKV VAQQLENDEI ISLPSTFGSS PRKQGEPSKL 

       190        200        210        220        230        240 
SKGKVNSKIY FVLFTLLIAI PATYYFSLDR FSRVQQGEQS MIEQHNQNVE MNDEHKNENV 

       250        260        270        280        290        300 
IEKLQNKLRT DPNNAETWLQ LGEAYVQNNE FDSALVAYSN AEKLSGSKPN ILGLAATALY 

       310        320        330        340        350        360 
YQAGQQMTQK VEQLLNEALA KDKNEVSSLS LLATIALENR QYQQAGMYLQ QLLDSGNAAV 

       370        380 
DRRSVIQRMK MLDFLQRGEK GQNP 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L42023 Genomic DNA. Translation: AAC22592.1.
PIRH64161.
RefSeqNP_439094.1. NC_000907.1.

3D structure databases

ProteinModelPortalP44942.
SMRP44942. Positions 37-114.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING71421.HI0934.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC22592; AAC22592; HI_0934.
GeneID949938.
KEGGhin:HI0934.
PATRIC20190525. VBIHaeInf48452_0975.

Phylogenomic databases

eggNOGCOG3088.
KOK04017.
K04018.
OMANSPIARD.
OrthoDBEOG679TDV.
ProtClustDBCLSK808468.

Family and domain databases

Gene3D1.25.40.10. 2 hits.
InterProIPR005616. Cyt_c_biogenesis_CcmH.
IPR017565. For-dep_Cytc_NO2Rdtase_NrfF.
IPR026930. NrfG.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical.
IPR019734. TPR_repeat.
[Graphical view]
PANTHERPTHR26312:SF64. PTHR26312:SF64. 1 hit.
PfamPF03918. CcmH. 1 hit.
[Graphical view]
TIGRFAMsTIGR03147. cyt_nit_nrfF. 1 hit.
PROSITEPS50005. TPR. 1 hit.
PS50293. TPR_REGION. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNRFF_HAEIN
AccessionPrimary (citable) accession number: P44942
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: June 6, 2002
Last modified: November 13, 2013
This is version 94 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names