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P44942

- NRFF_HAEIN

UniProt

P44942 - NRFF_HAEIN

Protein

Formate-dependent nitrite reductase complex bifunctional subunit NrfFG

Gene

nrfF

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 99 (01 Oct 2014)
      Sequence version 2 (06 Jun 2002)
      Previous versions | rss
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    Functioni

    Possible subunit of a heme lyase.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei61 – 611Heme (covalent)Sequence Analysis
    Binding sitei64 – 641Heme (covalent)Sequence Analysis

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW

    Keywords - Ligandi

    Heme, Iron, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Formate-dependent nitrite reductase complex bifunctional subunit NrfFG
    Gene namesi
    Name:nrfF
    Ordered Locus Names:HI_0934
    OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
    Taxonomic identifieri71421 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000000579: Chromosome

    Subcellular locationi

    Periplasm Curated

    GO - Cellular componenti

    1. periplasmic space Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Periplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 3535Sequence AnalysisAdd
    BLAST
    Chaini36 – 384349Formate-dependent nitrite reductase complex bifunctional subunit NrfFGPRO_0000006616Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi71421.HI0934.

    Structurei

    3D structure databases

    ProteinModelPortaliP44942.
    SMRiP44942. Positions 37-114.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati221 – 25434TPR 1Add
    BLAST
    Repeati255 – 28834TPR 2Add
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni36 – 144109NrfFAdd
    BLAST
    Regioni180 – 384205NrfGAdd
    BLAST

    Sequence similaritiesi

    Belongs to the CcmH/CycL/Ccl2/NrfF family.Curated
    Contains 2 TPR repeats.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, Signal, TPR repeat

    Phylogenomic databases

    eggNOGiCOG3088.
    KOiK04017.
    K04018.
    OMAiNSPIARD.
    OrthoDBiEOG679TDV.
    PhylomeDBiP44942.

    Family and domain databases

    Gene3Di1.25.40.10. 2 hits.
    InterProiIPR005616. Cyt_c_biogenesis_CcmH.
    IPR017565. For-dep_Cytc_NO2Rdtase_NrfF.
    IPR013026. TPR-contain_dom.
    IPR011990. TPR-like_helical.
    IPR019734. TPR_repeat.
    [Graphical view]
    PfamiPF03918. CcmH. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR03147. cyt_nit_nrfF. 1 hit.
    PROSITEiPS50005. TPR. 1 hit.
    PS50293. TPR_REGION. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P44942-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKSILDIFTR GFIQVQKTVF FATALLFAFS LFTQAEMVDT YQFQNQDDRT    50
    RAVELAKSLR CPQCQNQNLV ESNSPIAYDL RLEVYKMVDE GKSNQQIIDK 100
    MTARFGDFVN YKPPFKWNTA LLWLLPVALL ILAAVLLYFS NRKKQFSEKV 150
    VAQQLENDEI ISLPSTFGSS PRKQGEPSKL SKGKVNSKIY FVLFTLLIAI 200
    PATYYFSLDR FSRVQQGEQS MIEQHNQNVE MNDEHKNENV IEKLQNKLRT 250
    DPNNAETWLQ LGEAYVQNNE FDSALVAYSN AEKLSGSKPN ILGLAATALY 300
    YQAGQQMTQK VEQLLNEALA KDKNEVSSLS LLATIALENR QYQQAGMYLQ 350
    QLLDSGNAAV DRRSVIQRMK MLDFLQRGEK GQNP 384
    Length:384
    Mass (Da):43,780
    Last modified:June 6, 2002 - v2
    Checksum:i0321F4A7704964C4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22592.1.
    PIRiH64161.
    RefSeqiNP_439094.1. NC_000907.1.
    WP_005693281.1. NC_000907.1.

    Genome annotation databases

    EnsemblBacteriaiAAC22592; AAC22592; HI_0934.
    GeneIDi949938.
    KEGGihin:HI0934.
    PATRICi20190525. VBIHaeInf48452_0975.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22592.1 .
    PIRi H64161.
    RefSeqi NP_439094.1. NC_000907.1.
    WP_005693281.1. NC_000907.1.

    3D structure databases

    ProteinModelPortali P44942.
    SMRi P44942. Positions 37-114.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 71421.HI0934.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC22592 ; AAC22592 ; HI_0934 .
    GeneIDi 949938.
    KEGGi hin:HI0934.
    PATRICi 20190525. VBIHaeInf48452_0975.

    Phylogenomic databases

    eggNOGi COG3088.
    KOi K04017.
    K04018.
    OMAi NSPIARD.
    OrthoDBi EOG679TDV.
    PhylomeDBi P44942.

    Family and domain databases

    Gene3Di 1.25.40.10. 2 hits.
    InterProi IPR005616. Cyt_c_biogenesis_CcmH.
    IPR017565. For-dep_Cytc_NO2Rdtase_NrfF.
    IPR013026. TPR-contain_dom.
    IPR011990. TPR-like_helical.
    IPR019734. TPR_repeat.
    [Graphical view ]
    Pfami PF03918. CcmH. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR03147. cyt_nit_nrfF. 1 hit.
    PROSITEi PS50005. TPR. 1 hit.
    PS50293. TPR_REGION. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

    Entry informationi

    Entry nameiNRFF_HAEIN
    AccessioniPrimary (citable) accession number: P44942
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: June 6, 2002
    Last modified: October 1, 2014
    This is version 99 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Haemophilus influenzae
      Haemophilus influenzae (strain Rd): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3