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P44920 (COAE_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 90. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dephospho-CoA kinase
EC=2.7.1.24
Alternative name(s):
Dephosphocoenzyme A kinase
Gene names
Name:coaE
Ordered Locus Names:HI_0890
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length206 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A By similarity. HAMAP MF_00376

Catalytic activity

ATP + 3'-dephospho-CoA = ADP + CoA. HAMAP MF_00376

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5. HAMAP MF_00376

Subcellular location

Cytoplasm By similarity HAMAP MF_00376.

Sequence similarities

Belongs to the CoaE family.

Contains 1 DPCK (dephospho-CoA kinase) domain.

Sequence caution

The sequence AAC22550.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processCoenzyme A biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological processcoenzyme A biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

dephospho-CoA kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 206206Dephospho-CoA kinase HAMAP MF_00376
PRO_0000172947

Regions

Domain4 – 204201DPCK
Nucleotide binding9 – 168ATP Potential

Secondary structure

1 ................................. 206
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P44920 [UniParc].

Last modified June 1, 2001. Version 2.
Checksum: DF85B65D50131C01

FASTA20623,287
        10         20         30         40         50         60 
MTYIVGLTGG IGSGKTTIAN LFTDLGVPLV DADVVAREVV AKDSPLLSKI VEHFGAQILT 

        70         80         90        100        110        120 
EQGELNRAAL RERVFNHDED KLWLNNLLHP AIRERMKQKL AEQTAPYTLF VVPLLIENKL 

       130        140        150        160        170        180 
TALCDRILVV DVSPQTQLAR SAQRDNNNFE QIQRIMNSQV SQQERLKWAD DVINNDAELA 

       190        200 
QNLPHLQQKV LELHQFYLQQ AENKNA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L42023 Genomic DNA. Translation: AAC22550.1. Different initiation.
PIRA64161.
RefSeqNP_439051.1. NC_000907.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1JJVX-ray2.00A1-206[»]
ProteinModelPortalP44920.
SMRP44920. Positions 1-205.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID950766.
GenomeReviewsGene locus HI_0890 in contig L42023_GR.
NMPDRfig|71421.1.peg.857.
PATRIC20190437. VBIHaeInf48452_0932.
TIGRHI_0890.

Phylogenomic databases

HOGENOMHBG650290.
OMAYVIMVVP.
PhylomeDBP44920.
ProtClustDBPRK00081.

Enzyme and pathway databases

BioCycHINF71421:HI_0890-MONOMER.

Family and domain databases

HAMAPMF_00376. Dephospho_CoA_kinase.
[Tree]
InterProIPR001977. Depp_CoAkinase.
[Graphical view]
PfamPF01121. CoaE. 1 hit.
[Graphical view]
TIGRFAMsTIGR00152. TIGR00152. 1 hit.
PROSITEPS51219. DPCK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOAE_HAEIN
AccessionPrimary (citable) accession number: P44920
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: June 1, 2001
Last modified: January 25, 2012
This is version 90 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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