Reviewed, UniProtKB/Swiss-Prot P44878 (GALU_HAEIN)

Names and origin

Protein names

Recommended name:
    UTP--glucose-1-phosphate uridylyltransferase
    EC=2.7.7.9
Alternative name(s):
    UDP-glucose pyrophosphorylase
      Short name=UDPGP
    Alpha-D-glucosyl-1-phosphate uridylyltransferase
    Uridine diphosphoglucose pyrophosphorylase

Gene names

Name:	galU
Ordered Locus Names:	HI0812

Organism

Haemophilus influenzae [Complete proteome] [HAMAP]

Taxonomic identifier

727 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	295 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	May play a role in stationary phase survival By similarity.
Catalytic activity	UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.
Sequence similarities	Belongs to the UDPGP type 2 family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	UDP-glucose metabolic process Inferred from electronic annotation. Source: InterPro biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	UTP:glucose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 295	295	UTP--glucose-1-phosphate uridylyltransferase		PRO_0000201358

Sequences

	Sequence		Length	Mass (Da)
	P44878-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: FED84173957E571B	FASTA	295	32,279
	10 20 30 40 50 60 MKAVIPVAGL GTRMLPATKA IPKEMLTLVD KPLIQYVVNE CVAAGIKEIV LVTHSSKNAI 70 80 90 100 110 120 ENHFDTSFEL ETMLEKRVKR QLLEEVRSIC PKNVTIMHVR QGNAKGLGHA VLCGRPLVGN 130 140 150 160 170 180 ESFAVMLPDV LLAEFSADQK KENLAAMIQR FNETGASQIM VTPVPQENVS SYGVADCGGI 190 200 210 220 230 240 ELNGGESAKI NSIVEKPSIE DAPSNLAVVG RYVFSAAIWD LLEKTPIGVG DEIQLTDAID 250 260 270 280 290 MLIEKETVEA FHMTGETFDC GDKIGYMEAF VEYGIRHEKL GKEFKSFIKN LAKTL

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L42023 Genomic DNA. Translation: AAC22471.1.
PIR	G64095.
RefSeq	NP_438972.1.
3D structure databases
SMR	P44878. Positions 2-289.
ModBase	Search...
Genome annotation databases
GeneID	949826.
GenomeReviews	Gene locus HI0812 in contig L42023_GR.
KEGG	hin:HI0812.
NMPDR	fig|71421.1.peg.780.
TIGR	HI0812.
Phylogenomic databases
HOGENOM	P44878.
OMA	GFIETTL.
Enzyme and pathway databases
BioCyc	HINF71421:HI_0812-MON.
BRENDA	2.7.7.9. 109.
Family and domain databases
InterPro	IPR005771. GalU_uridylyltTrfase_bac/arc. IPR005835. NTP_transferase. [Graphical view]
Pfam	PF00483. NTP_transferase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01099. galU. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GALU_HAEIN

Accession

Primary (citable) accession number: P44878

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	November 3, 2009
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)