Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

UTP--glucose-1-phosphate uridylyltransferase

Gene

galU

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May play a role in stationary phase survival.By similarity

Catalytic activityi

UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.

GO - Molecular functioni

  1. UTP:glucose-1-phosphate uridylyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. biosynthetic process Source: InterPro
  2. UDP-glucose metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
UTP--glucose-1-phosphate uridylyltransferase (EC:2.7.7.9)
Alternative name(s):
Alpha-D-glucosyl-1-phosphate uridylyltransferase
UDP-glucose pyrophosphorylase
Short name:
UDPGP
Uridine diphosphoglucose pyrophosphorylase
Gene namesi
Name:galU
Ordered Locus Names:HI_0812
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 295295UTP--glucose-1-phosphate uridylyltransferasePRO_0000201358Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0812.

Structurei

3D structure databases

ProteinModelPortaliP44878.
SMRiP44878. Positions 2-289.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UDPGP type 2 family.Curated

Phylogenomic databases

eggNOGiCOG1210.
KOiK00963.
OMAiKVERYGI.
OrthoDBiEOG6Z9B3V.
PhylomeDBiP44878.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR005771. GalU_uridylyltTrfase_bac/arc.
IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.
TIGRFAMsiTIGR01099. galU. 1 hit.

Sequencei

Sequence statusi: Complete.

P44878-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKAVIPVAGL GTRMLPATKA IPKEMLTLVD KPLIQYVVNE CVAAGIKEIV
60 70 80 90 100
LVTHSSKNAI ENHFDTSFEL ETMLEKRVKR QLLEEVRSIC PKNVTIMHVR
110 120 130 140 150
QGNAKGLGHA VLCGRPLVGN ESFAVMLPDV LLAEFSADQK KENLAAMIQR
160 170 180 190 200
FNETGASQIM VTPVPQENVS SYGVADCGGI ELNGGESAKI NSIVEKPSIE
210 220 230 240 250
DAPSNLAVVG RYVFSAAIWD LLEKTPIGVG DEIQLTDAID MLIEKETVEA
260 270 280 290
FHMTGETFDC GDKIGYMEAF VEYGIRHEKL GKEFKSFIKN LAKTL
Length:295
Mass (Da):32,279
Last modified:November 1, 1995 - v1
Checksum:iFED84173957E571B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22471.1.
PIRiG64095.
RefSeqiNP_438972.1. NC_000907.1.
WP_005693178.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22471; AAC22471; HI_0812.
GeneIDi949826.
KEGGihin:HI0812.
PATRICi20190279. VBIHaeInf48452_0853.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22471.1.
PIRiG64095.
RefSeqiNP_438972.1. NC_000907.1.
WP_005693178.1. NC_000907.1.

3D structure databases

ProteinModelPortaliP44878.
SMRiP44878. Positions 2-289.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi71421.HI0812.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC22471; AAC22471; HI_0812.
GeneIDi949826.
KEGGihin:HI0812.
PATRICi20190279. VBIHaeInf48452_0853.

Phylogenomic databases

eggNOGiCOG1210.
KOiK00963.
OMAiKVERYGI.
OrthoDBiEOG6Z9B3V.
PhylomeDBiP44878.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR005771. GalU_uridylyltTrfase_bac/arc.
IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.
TIGRFAMsiTIGR01099. galU. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiGALU_HAEIN
AccessioniPrimary (citable) accession number: P44878
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: February 4, 2015
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.