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P44861 (ANMK_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Anhydro-N-acetylmuramic acid kinase

EC=2.7.1.170
Alternative name(s):
AnhMurNAc kinase
Gene names
Name:anmK
Ordered Locus Names:HI_0753
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length382 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling By similarity. HAMAP-Rule MF_01270

Catalytic activity

ATP + 1,6-anhydro-N-acetyl-beta-muramate + H2O = ADP + N-acetylmuramate 6-phosphate. HAMAP-Rule MF_01270

Pathway

Amino-sugar metabolism; 1,6-anhydro-N-acetylmuramate degradation. HAMAP-Rule MF_01270

Cell wall biogenesis; peptidoglycan recycling. HAMAP-Rule MF_01270

Sequence similarities

Belongs to the anhydro-N-acetylmuramic acid kinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 382382Anhydro-N-acetylmuramic acid kinase HAMAP-Rule MF_01270
PRO_0000214822

Regions

Nucleotide binding15 – 228ATP Potential

Sequences

Sequence LengthMass (Da)Tools
P44861 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: D14E353287BC11A6

FASTA38242,026
        10         20         30         40         50         60 
MINMKPQYYL GMMSGTSLDG VDIVLVDFSQ DPQLILSDFF PMPEDLREKL TTLIQVGETT 

        70         80         90        100        110        120 
LQNLGELDHK LALLYSDCVN AFLQKNTFLP NQIQAIGCHG QTVWHSPNSQ FPFTMQLGDM 

       130        140        150        160        170        180 
NLLAAKTGIS VIGDFRRKDM AWGGQGAPLV PAFHEAVFSN SNFATAVLNI GGISNVSILF 

       190        200        210        220        230        240 
PNQAVIGFDT GPGNTLLDQW IEKHQGLRYD ENGEWAAKGN VNKVLLDELL NEPFFSLPAP 

       250        260        270        280        290        300 
KSTGRELFNL VWLNHKIAKI REKLTALSVE MSFRPEDVQA TLVELTVTSI VNALNQLQTD 

       310        320        330        340        350        360 
LPKRLLVCGG GAKNSLIMRG LHDNLLDWQV STTTEQGFDI DYVEAAAFAW LAYCRINNLP 

       370        380 
ANLPSVTGAK SAVSLGAIFP KD 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L42023 Genomic DNA. Translation: AAC22412.1.
PIRB64158.
RefSeqNP_438912.1. NC_000907.1.

3D structure databases

ProteinModelPortalP44861.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING71421.HI0753.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC22412; AAC22412; HI_0753.
GeneID949467.
KEGGhin:HI0753.
PATRIC20190151. VBIHaeInf48452_0791.

Phylogenomic databases

eggNOGCOG2377.
KOK09001.
OMAGRYIGVM.
OrthoDBEOG64N9WW.
PhylomeDBP44861.

Enzyme and pathway databases

UniPathwayUPA00343.
UPA00544.

Family and domain databases

HAMAPMF_01270. AnhMurNAc_kinase.
InterProIPR005338. Anhydro_N_Ac-Mur_kinase.
[Graphical view]
PfamPF03702. UPF0075. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameANMK_HAEIN
AccessionPrimary (citable) accession number: P44861
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: July 9, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names