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P44856

- DHNA_HAEIN

UniProt

P44856 - DHNA_HAEIN

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Protein
NADH dehydrogenase
Gene
ndh, HI_0747
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation By similarity.

Catalytic activityi

NADH + acceptor = NAD+ + reduced acceptor.

Cofactori

Binds 1 FAD per subunit By similarity.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi3 – 3836FAD By similarity
Add
BLAST
Nucleotide bindingi181 – 21838NAD By similarity
Add
BLAST

GO - Molecular functioni

  1. NADH dehydrogenase activity Source: UniProtKB-EC
  2. flavin adenine dinucleotide binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

FAD, Flavoprotein, NAD, Ubiquinone

Names & Taxonomyi

Protein namesi
Recommended name:
NADH dehydrogenase (EC:1.6.99.3)
Gene namesi
Name:ndh
Ordered Locus Names:HI_0747
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579: Chromosome

Subcellular locationi

Cell membrane By similarity

GO - Cellular componenti

  1. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 444444NADH dehydrogenase
PRO_0000079891Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0747.

Structurei

3D structure databases

ProteinModelPortaliP44856.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1252.
KOiK03885.
OMAiSHKDVFV.
OrthoDBiEOG6QZMR6.
PhylomeDBiP44856.

Family and domain databases

InterProiIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
[Graphical view]
PfamiPF00070. Pyr_redox. 2 hits.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSiPR00368. FADPNR.

Sequencei

Sequence statusi: Complete.

P44856-1 [UniParc]FASTAAdd to Basket

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MKNVVIVGGG AGGIELATFL GNKLGRQKQA KVTLVDRNAT HLWKPLLHEI    50
ATGVMDDGVD SLSYRAHGKN HFFSFEQGSI IRINREQKYV ELAPVYGQEG 100
DMLVIARRIP YDYLVIAIGS KSNDFNTKGV ADNCIFLDSS KQALRFQHKL 150
LELFLKFSEN RALDDIGEEE FKQKLVDENK VNIAIVGGGA TGVELTAELY 200
HAAEDLSSYG YGKIDSSCLQ VTLVEAGTRL LPALPENLSA AVLDELKEMG 250
TNVQLNTMIT EAQPNTLITK DGGEIKADLI VWAAGVRAST VTQQFDGLEI 300
NRINQLVVKD TLQTTVDDSI FAIGDCAALI QSNGKLVPPR AQAAHQMAKA 350
CAKNIFALFE NKPLKSFKYN DKGTLVSLSN FTALGSLTNK FGKNPLTVQG 400
KFAQFAYVSL YRMHQHALHG CIKIGLIILV DKLNRYLKPR LKLH 444
Length:444
Mass (Da):48,778
Last modified:November 1, 1995 - v1
Checksum:iB0EFE3613FE6B78B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC22405.1.
PIRiC64090.
RefSeqiNP_438906.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22405; AAC22405; HI_0747.
GeneIDi949772.
KEGGihin:HI0747.
PATRICi20190137. VBIHaeInf48452_0784.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC22405.1 .
PIRi C64090.
RefSeqi NP_438906.1. NC_000907.1.

3D structure databases

ProteinModelPortali P44856.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 71421.HI0747.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC22405 ; AAC22405 ; HI_0747 .
GeneIDi 949772.
KEGGi hin:HI0747.
PATRICi 20190137. VBIHaeInf48452_0784.

Phylogenomic databases

eggNOGi COG1252.
KOi K03885.
OMAi SHKDVFV.
OrthoDBi EOG6QZMR6.
PhylomeDBi P44856.

Family and domain databases

InterProi IPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
[Graphical view ]
Pfami PF00070. Pyr_redox. 2 hits.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view ]
PRINTSi PR00368. FADPNR.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiDHNA_HAEIN
AccessioniPrimary (citable) accession number: P44856
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: July 9, 2014
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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