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P44856

- DHNA_HAEIN

UniProt

P44856 - DHNA_HAEIN

Protein

NADH dehydrogenase

Gene

ndh

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 101 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation By similarity.By similarity

    Catalytic activityi

    NADH + acceptor = NAD+ + reduced acceptor.

    Cofactori

    Binds 1 FAD per subunit.By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi3 – 3836FADBy similarityAdd
    BLAST
    Nucleotide bindingi181 – 21838NADBy similarityAdd
    BLAST

    GO - Molecular functioni

    1. flavin adenine dinucleotide binding Source: InterPro
    2. NADH dehydrogenase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Electron transport, Transport

    Keywords - Ligandi

    FAD, Flavoprotein, NAD, Ubiquinone

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    NADH dehydrogenase (EC:1.6.99.3)
    Gene namesi
    Name:ndh
    Ordered Locus Names:HI_0747
    OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
    Taxonomic identifieri71421 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000000579: Chromosome

    Subcellular locationi

    Cell membrane By similarity

    GO - Cellular componenti

    1. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 444444NADH dehydrogenasePRO_0000079891Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi71421.HI0747.

    Structurei

    3D structure databases

    ProteinModelPortaliP44856.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the NADH dehydrogenase family.Curated

    Phylogenomic databases

    eggNOGiCOG1252.
    KOiK03885.
    OMAiSHKDVFV.
    OrthoDBiEOG6QZMR6.
    PhylomeDBiP44856.

    Family and domain databases

    InterProiIPR013027. FAD_pyr_nucl-diS_OxRdtase.
    IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
    IPR001327. Pyr_OxRdtase_NAD-bd_dom.
    [Graphical view]
    PfamiPF00070. Pyr_redox. 2 hits.
    PF07992. Pyr_redox_2. 1 hit.
    [Graphical view]
    PRINTSiPR00368. FADPNR.

    Sequencei

    Sequence statusi: Complete.

    P44856-1 [UniParc]FASTAAdd to Basket

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    MKNVVIVGGG AGGIELATFL GNKLGRQKQA KVTLVDRNAT HLWKPLLHEI    50
    ATGVMDDGVD SLSYRAHGKN HFFSFEQGSI IRINREQKYV ELAPVYGQEG 100
    DMLVIARRIP YDYLVIAIGS KSNDFNTKGV ADNCIFLDSS KQALRFQHKL 150
    LELFLKFSEN RALDDIGEEE FKQKLVDENK VNIAIVGGGA TGVELTAELY 200
    HAAEDLSSYG YGKIDSSCLQ VTLVEAGTRL LPALPENLSA AVLDELKEMG 250
    TNVQLNTMIT EAQPNTLITK DGGEIKADLI VWAAGVRAST VTQQFDGLEI 300
    NRINQLVVKD TLQTTVDDSI FAIGDCAALI QSNGKLVPPR AQAAHQMAKA 350
    CAKNIFALFE NKPLKSFKYN DKGTLVSLSN FTALGSLTNK FGKNPLTVQG 400
    KFAQFAYVSL YRMHQHALHG CIKIGLIILV DKLNRYLKPR LKLH 444
    Length:444
    Mass (Da):48,778
    Last modified:November 1, 1995 - v1
    Checksum:iB0EFE3613FE6B78B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22405.1.
    PIRiC64090.
    RefSeqiNP_438906.1. NC_000907.1.

    Genome annotation databases

    EnsemblBacteriaiAAC22405; AAC22405; HI_0747.
    GeneIDi949772.
    KEGGihin:HI0747.
    PATRICi20190137. VBIHaeInf48452_0784.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22405.1 .
    PIRi C64090.
    RefSeqi NP_438906.1. NC_000907.1.

    3D structure databases

    ProteinModelPortali P44856.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 71421.HI0747.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC22405 ; AAC22405 ; HI_0747 .
    GeneIDi 949772.
    KEGGi hin:HI0747.
    PATRICi 20190137. VBIHaeInf48452_0784.

    Phylogenomic databases

    eggNOGi COG1252.
    KOi K03885.
    OMAi SHKDVFV.
    OrthoDBi EOG6QZMR6.
    PhylomeDBi P44856.

    Family and domain databases

    InterProi IPR013027. FAD_pyr_nucl-diS_OxRdtase.
    IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
    IPR001327. Pyr_OxRdtase_NAD-bd_dom.
    [Graphical view ]
    Pfami PF00070. Pyr_redox. 2 hits.
    PF07992. Pyr_redox_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00368. FADPNR.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

    Entry informationi

    Entry nameiDHNA_HAEIN
    AccessioniPrimary (citable) accession number: P44856
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 101 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Haemophilus influenzae
      Haemophilus influenzae (strain Rd): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3