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Protein

Protein-export protein SecB

Gene

secB

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Protein transport, Translocation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Protein-export protein SecB
Gene namesi
Name:secB
Ordered Locus Names:HI_0743
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000000579 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000553781 – 169Protein-export protein SecBAdd BLAST169

Interactioni

Subunit structurei

Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.

Protein-protein interaction databases

IntActiP44853. 1 interactor.
STRINGi71421.HI0743.

Structurei

Secondary structure

1169
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi17 – 31Combined sources15
Helixi35 – 38Combined sources4
Beta strandi51 – 59Combined sources9
Beta strandi62 – 71Combined sources10
Turni76 – 78Combined sources3
Beta strandi84 – 97Combined sources14
Helixi100 – 108Combined sources9
Helixi110 – 129Combined sources20
Helixi142 – 156Combined sources15
Helixi158 – 161Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1FX3X-ray2.50A/B/C/D1-169[»]
1OZBX-ray2.80A/B/C/D/E/F/G/H1-169[»]
ProteinModelPortaliP44853.
SMRiP44853.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP44853.

Family & Domainsi

Sequence similaritiesi

Belongs to the SecB family.Curated

Phylogenomic databases

eggNOGiENOG4105IX2. Bacteria.
COG1952. LUCA.
KOiK03071.
OMAiCPNVLFP.
PhylomeDBiP44853.

Family and domain databases

Gene3Di3.10.420.10. 1 hit.
HAMAPiMF_00821. SecB. 1 hit.
InterProiIPR003708. SecB.
[Graphical view]
PfamiPF02556. SecB. 1 hit.
[Graphical view]
PRINTSiPR01594. SECBCHAPRONE.
SUPFAMiSSF54611. SSF54611. 1 hit.
TIGRFAMsiTIGR00809. secB. 1 hit.

Sequencei

Sequence statusi: Complete.

P44853-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEQKQDVAA TEEQQPVLQI QRIYVKDVSF EAPNLPHIFQ QEWKPKLGFD
60 70 80 90 100
LSTETTQVGD DLYEVVLNIS VETTLEDSGD VAFICEVKQA GVFTISGLED
110 120 130 140 150
VQMAHCLTSQ CPNMLFPYAR ELVSNLVNRG TFPALNLSPV NFDALFVEYM
160
NRQQAENAEE KSEEEQTKH
Length:169
Mass (Da):19,132
Last modified:November 1, 1995 - v1
Checksum:i047DCC722965EC7B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22401.1.
PIRiI64089.
RefSeqiNP_438902.1. NC_000907.1.
WP_005630575.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22401; AAC22401; HI_0743.
GeneIDi949770.
KEGGihin:HI0743.
PATRICi20190127. VBIHaeInf48452_0779.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22401.1.
PIRiI64089.
RefSeqiNP_438902.1. NC_000907.1.
WP_005630575.1. NC_000907.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1FX3X-ray2.50A/B/C/D1-169[»]
1OZBX-ray2.80A/B/C/D/E/F/G/H1-169[»]
ProteinModelPortaliP44853.
SMRiP44853.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP44853. 1 interactor.
STRINGi71421.HI0743.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC22401; AAC22401; HI_0743.
GeneIDi949770.
KEGGihin:HI0743.
PATRICi20190127. VBIHaeInf48452_0779.

Phylogenomic databases

eggNOGiENOG4105IX2. Bacteria.
COG1952. LUCA.
KOiK03071.
OMAiCPNVLFP.
PhylomeDBiP44853.

Miscellaneous databases

EvolutionaryTraceiP44853.

Family and domain databases

Gene3Di3.10.420.10. 1 hit.
HAMAPiMF_00821. SecB. 1 hit.
InterProiIPR003708. SecB.
[Graphical view]
PfamiPF02556. SecB. 1 hit.
[Graphical view]
PRINTSiPR01594. SECBCHAPRONE.
SUPFAMiSSF54611. SSF54611. 1 hit.
TIGRFAMsiTIGR00809. secB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSECB_HAEIN
AccessioniPrimary (citable) accession number: P44853
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: November 2, 2016
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.