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Protein

Outer membrane antigenic lipoprotein B

Gene

lppB

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May be a virulence determinant.

GO - Biological processi

  1. pathogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Virulence

Names & Taxonomyi

Protein namesi
Recommended name:
Outer membrane antigenic lipoprotein B
Gene namesi
Name:lppB
Ordered Locus Names:HI_0706
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cell outer membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717CuratedAdd
BLAST
Chaini18 – 405388Outer membrane antigenic lipoprotein BPRO_0000018034Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi18 – 181N-palmitoyl cysteineCurated
Lipidationi18 – 181S-diacylglycerol cysteineCurated

Keywords - PTMi

Lipoprotein, Palmitate

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0706.

Structurei

3D structure databases

ProteinModelPortaliP44833.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati147 – 19044LysMAdd
BLAST

Sequence similaritiesi

Contains 1 LysM repeat.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG0739.
KOiK06194.
OMAiWITGNDY.
OrthoDBiEOG61ZTBJ.
PhylomeDBiP44833.

Family and domain databases

Gene3Di3.10.350.10. 1 hit.
InterProiIPR011055. Dup_hybrid_motif.
IPR018392. LysM_dom.
IPR016047. Peptidase_M23.
[Graphical view]
PfamiPF01476. LysM. 1 hit.
PF01551. Peptidase_M23. 1 hit.
[Graphical view]
SMARTiSM00257. LysM. 1 hit.
[Graphical view]
SUPFAMiSSF51261. SSF51261. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P44833-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKSFLLLPL SLVVLSACTS NFPAPISDAD GNFSPSVIQS VNGSNVGGAW
60 70 80 90 100
QPEIQKNSLP TTGNMVTPQQ NFQPINQQPT MPTAPAQPAF QPSPKTVVSA
110 120 130 140 150
PTVQTKTVTK TVADCVDGQH INIPRNPNTN APDYSKISKG SYKGNTYKVN
160 170 180 190 200
KGDTMFLIAY LAGIDVKELA ALNNLSEPYN LSLGQVLKIS NCDIKTVTTT
210 220 230 240 250
VSVKQPAVTA STATPVKPAV TYTPGANGTQ IGSDGTIIGP IKSEAGTSPS
260 270 280 290 300
VPVATSSTQV TSSVNNANST PINSNVVAPI ASNVVWQWPT SGNIIQGFSS
310 320 330 340 350
TDGGNKGIDI SGSRGQAVKA AAAGRIVYAG NALRGYGNLI IIKHNDDFLS
360 370 380 390 400
AYAHNDKILV ADQQEVKAGQ DIAKMGSSGT NTVKLHFEIR YKGKSVDPVR

YLPRH
Length:405
Mass (Da):42,505
Last modified:October 31, 1995 - v1
Checksum:i4134FB6B93EFE57F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22363.1.
PIRiF64087.
RefSeqiNP_438864.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22363; AAC22363; HI_0706.
GeneIDi949731.
KEGGihin:HI0706.
PATRICi20190029. VBIHaeInf48452_0736.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22363.1.
PIRiF64087.
RefSeqiNP_438864.1. NC_000907.1.

3D structure databases

ProteinModelPortaliP44833.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi71421.HI0706.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC22363; AAC22363; HI_0706.
GeneIDi949731.
KEGGihin:HI0706.
PATRICi20190029. VBIHaeInf48452_0736.

Phylogenomic databases

eggNOGiCOG0739.
KOiK06194.
OMAiWITGNDY.
OrthoDBiEOG61ZTBJ.
PhylomeDBiP44833.

Family and domain databases

Gene3Di3.10.350.10. 1 hit.
InterProiIPR011055. Dup_hybrid_motif.
IPR018392. LysM_dom.
IPR016047. Peptidase_M23.
[Graphical view]
PfamiPF01476. LysM. 1 hit.
PF01551. Peptidase_M23. 1 hit.
[Graphical view]
SMARTiSM00257. LysM. 1 hit.
[Graphical view]
SUPFAMiSSF51261. SSF51261. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiLPPB_HAEIN
AccessioniPrimary (citable) accession number: P44833
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 1995
Last sequence update: October 31, 1995
Last modified: February 3, 2015
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.