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P44828

- PPX_HAEIN

UniProt

P44828 - PPX_HAEIN

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Protein
Putative exopolyphosphatase
Gene
ppx, HI_0695
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 3 out of 5 - Protein uncertaini

Functioni

Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate.

Catalytic activityi

(Polyphosphate)(n) + H2O = (polyphosphate)(n-1) + phosphate.

Cofactori

Magnesium By similarity.

GO - Molecular functioni

  1. exopolyphosphatase activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. polyphosphate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Magnesium

Names & Taxonomyi

Protein namesi
Recommended name:
Putative exopolyphosphatase (EC:3.6.1.11)
Alternative name(s):
Metaphosphatase
Gene namesi
Name:ppx
Ordered Locus Names:HI_0695
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 323323Putative exopolyphosphatase
PRO_0000194302Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0695.

Structurei

3D structure databases

ProteinModelPortaliP44828.
SMRiP44828. Positions 16-321.

Family & Domainsi

Sequence similaritiesi

Belongs to the GppA/Ppx family.

Phylogenomic databases

eggNOGiCOG0248.
KOiK01524.
OMAiAKHFTEL.
OrthoDBiEOG6M6JN6.
PhylomeDBiP44828.

Family and domain databases

InterProiIPR022371. Exopolyphosphatase.
IPR003695. Ppx_GppA.
[Graphical view]
PfamiPF02541. Ppx-GppA. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03706. exo_poly_only. 1 hit.

Sequencei

Sequence statusi: Complete.

P44828-1 [UniParc]FASTAAdd to Basket

« Hide

MNDSILEPKH RGNVREIAAI DLGSNSFHMI VARIVNGSIQ VLSRLKQKVK    50
LAEGLDENAV LNQEAITRGV NCLALFAERL QGFPMENVNV VGTYTLRRAV 100
NNDEFLRQAA KVFPYPINII SGQTEAKTIY AGVCHTQPEK GRKLVIDIGG 150
GSTEMIIGDD FTPLMAESRH MGCVSFATQF FTDGIISPEN FQRARQSAVN 200
KIEDLGLEYR KLGWQSVLGS SGTIKTVAQV IATNLDPNGT ITAERLNALI 250
EQTLQAKHFT ELNINGLNQD RVDVFVPGLA ILSAVFDVFH IQQMRYSDGA 300
LREGVIYSLE KNFQVADIRA STA 323
Length:323
Mass (Da):35,566
Last modified:November 1, 1995 - v1
Checksum:i5B7E9BBEFE780FB6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC22355.1.
PIRiC64087.
RefSeqiNP_438855.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22355; AAC22355; HI_0695.
GeneIDi950213.
KEGGihin:HI0695.
PATRICi20190011. VBIHaeInf48452_0727.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC22355.1 .
PIRi C64087.
RefSeqi NP_438855.1. NC_000907.1.

3D structure databases

ProteinModelPortali P44828.
SMRi P44828. Positions 16-321.
ModBasei Search...

Protein-protein interaction databases

STRINGi 71421.HI0695.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC22355 ; AAC22355 ; HI_0695 .
GeneIDi 950213.
KEGGi hin:HI0695.
PATRICi 20190011. VBIHaeInf48452_0727.

Phylogenomic databases

eggNOGi COG0248.
KOi K01524.
OMAi AKHFTEL.
OrthoDBi EOG6M6JN6.
PhylomeDBi P44828.

Family and domain databases

InterProi IPR022371. Exopolyphosphatase.
IPR003695. Ppx_GppA.
[Graphical view ]
Pfami PF02541. Ppx-GppA. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR03706. exo_poly_only. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiPPX_HAEIN
AccessioniPrimary (citable) accession number: P44828
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: July 9, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

Could be the product of a pseudogene. Compared with other ppx it lacks 200 residues at the C-terminal region.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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