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Protein

Putative exopolyphosphatase

Gene

ppx

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain.By similarity

Caution

Could be the product of a pseudogene. Compared with other ppx it lacks 200 residues at the C-terminal region.Curated

Catalytic activityi

(Polyphosphate)(n) + H2O = (polyphosphate)(n-1) + phosphate.By similarity

Cofactori

Mg2+By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandMagnesium

Enzyme and pathway databases

BioCyciHINF71421:G1GJ1-730-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative exopolyphosphataseBy similarity (EC:3.6.1.11By similarity)
Short name:
ExopolyPaseBy similarity
Gene namesi
Name:ppx
Ordered Locus Names:HI_0695
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000000579 Componenti: Chromosome

Subcellular locationi

  • Cell membrane By similarity; Peripheral membrane protein By similarity

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001943021 – 323Putative exopolyphosphataseAdd BLAST323

Proteomic databases

PRIDEiP44828

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi71421.HI0695

Structurei

3D structure databases

ProteinModelPortaliP44828
SMRiP44828
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GppA/Ppx family.Curated

Phylogenomic databases

eggNOGiENOG4105C9X Bacteria
COG0248 LUCA
KOiK01524
OMAiVMHPGRV
PhylomeDBiP44828

Family and domain databases

InterProiView protein in InterPro
IPR022371 Exopolyphosphatase
IPR003695 Ppx_GppA
PfamiView protein in Pfam
PF02541 Ppx-GppA, 1 hit
TIGRFAMsiTIGR03706 exo_poly_only, 1 hit

Sequencei

Sequence statusi: Complete.

P44828-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNDSILEPKH RGNVREIAAI DLGSNSFHMI VARIVNGSIQ VLSRLKQKVK
60 70 80 90 100
LAEGLDENAV LNQEAITRGV NCLALFAERL QGFPMENVNV VGTYTLRRAV
110 120 130 140 150
NNDEFLRQAA KVFPYPINII SGQTEAKTIY AGVCHTQPEK GRKLVIDIGG
160 170 180 190 200
GSTEMIIGDD FTPLMAESRH MGCVSFATQF FTDGIISPEN FQRARQSAVN
210 220 230 240 250
KIEDLGLEYR KLGWQSVLGS SGTIKTVAQV IATNLDPNGT ITAERLNALI
260 270 280 290 300
EQTLQAKHFT ELNINGLNQD RVDVFVPGLA ILSAVFDVFH IQQMRYSDGA
310 320
LREGVIYSLE KNFQVADIRA STA
Length:323
Mass (Da):35,566
Last modified:November 1, 1995 - v1
Checksum:i5B7E9BBEFE780FB6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA Translation: AAC22355.1
PIRiC64087
RefSeqiNP_438855.1, NC_000907.1
WP_005694580.1, NC_000907.1

Genome annotation databases

EnsemblBacteriaiAAC22355; AAC22355; HI_0695
GeneIDi950213
KEGGihin:HI0695
PATRICifig|71421.8.peg.727

Similar proteinsi

Entry informationi

Entry nameiPPX_HAEIN
AccessioniPrimary (citable) accession number: P44828
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 23, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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