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P44828 (PPX_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative exopolyphosphatase
EC=3.6.1.11
Alternative name(s):
Metaphosphatase
Gene names
Name:ppx
Ordered Locus Names:HI_0695
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus ›

Protein attributes

Sequence length323 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Function

Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate.

Catalytic activity

(Polyphosphate)(n) + H2O = (polyphosphate)(n-1) + phosphate.

Cofactor

Magnesium By similarity.

Subcellular location

Cell membrane; Peripheral membrane protein Potential.

Sequence similarities

Belongs to the GppA/Ppx family.

Caution

Could be the product of a pseudogene. Compared with other ppx it lacks 200 residues at the C-terminal region.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   LigandMagnesium
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processpolyphosphate catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentplasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionexopolyphosphatase activity

Inferred from electronic annotation. Source: EC

magnesium ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 323323Putative exopolyphosphatase
PRO_0000194302

Sequences

Sequence LengthMass (Da)Tools
P44828 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 5B7E9BBEFE780FB6

FASTA32335,566
        10         20         30         40         50         60 
MNDSILEPKH RGNVREIAAI DLGSNSFHMI VARIVNGSIQ VLSRLKQKVK LAEGLDENAV 

        70         80         90        100        110        120 
LNQEAITRGV NCLALFAERL QGFPMENVNV VGTYTLRRAV NNDEFLRQAA KVFPYPINII 

       130        140        150        160        170        180 
SGQTEAKTIY AGVCHTQPEK GRKLVIDIGG GSTEMIIGDD FTPLMAESRH MGCVSFATQF 

       190        200        210        220        230        240 
FTDGIISPEN FQRARQSAVN KIEDLGLEYR KLGWQSVLGS SGTIKTVAQV IATNLDPNGT 

       250        260        270        280        290        300 
ITAERLNALI EQTLQAKHFT ELNINGLNQD RVDVFVPGLA ILSAVFDVFH IQQMRYSDGA 

       310        320 
LREGVIYSLE KNFQVADIRA STA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L42023 Genomic DNA. Translation: AAC22355.1.
PIRC64087.
RefSeqNP_438855.1. NC_000907.1.

3D structure databases

ProteinModelPortalP44828.
SMRP44828. Positions 16-321.
ModBaseSearch...

Protein-protein interaction databases

STRING71421.HI0695.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC22355; AAC22355; HI_0695.
GeneID950213.
KEGGhin:HI0695.
PATRIC20190011. VBIHaeInf48452_0727.

Phylogenomic databases

eggNOGCOG0248.
KOK01524.
OMADRVIFSE.
ProtClustDBCLSK808440.

Family and domain databases

InterProIPR022371. Exopolyphosphatase.
IPR003695. Ppx_GppA.
[Graphical view]
PfamPF02541. Ppx-GppA. 1 hit.
[Graphical view]
TIGRFAMsTIGR03706. exo_poly_only. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPX_HAEIN
AccessionPrimary (citable) accession number: P44828
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 1, 2013
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names

SIMILARITY comments

Index of protein domains and families

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