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P44828

- PPX_HAEIN

UniProt

P44828 - PPX_HAEIN

Protein

Putative exopolyphosphatase

Gene

ppx

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 3 out of 5- Protein uncertaini
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    • History
      Entry version 89 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate.

    Catalytic activityi

    (Polyphosphate)(n) + H2O = (polyphosphate)(n-1) + phosphate.

    Cofactori

    Magnesium.By similarity

    GO - Molecular functioni

    1. exopolyphosphatase activity Source: UniProtKB-EC
    2. magnesium ion binding Source: InterPro

    GO - Biological processi

    1. polyphosphate catabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Ligandi

    Magnesium

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative exopolyphosphatase (EC:3.6.1.11)
    Alternative name(s):
    Metaphosphatase
    Gene namesi
    Name:ppx
    Ordered Locus Names:HI_0695
    OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
    Taxonomic identifieri71421 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000000579: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 323323Putative exopolyphosphatasePRO_0000194302Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi71421.HI0695.

    Structurei

    3D structure databases

    ProteinModelPortaliP44828.
    SMRiP44828. Positions 16-321.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GppA/Ppx family.Curated

    Phylogenomic databases

    eggNOGiCOG0248.
    KOiK01524.
    OMAiAKHFTEL.
    OrthoDBiEOG6M6JN6.
    PhylomeDBiP44828.

    Family and domain databases

    InterProiIPR022371. Exopolyphosphatase.
    IPR003695. Ppx_GppA.
    [Graphical view]
    PfamiPF02541. Ppx-GppA. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR03706. exo_poly_only. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P44828-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNDSILEPKH RGNVREIAAI DLGSNSFHMI VARIVNGSIQ VLSRLKQKVK    50
    LAEGLDENAV LNQEAITRGV NCLALFAERL QGFPMENVNV VGTYTLRRAV 100
    NNDEFLRQAA KVFPYPINII SGQTEAKTIY AGVCHTQPEK GRKLVIDIGG 150
    GSTEMIIGDD FTPLMAESRH MGCVSFATQF FTDGIISPEN FQRARQSAVN 200
    KIEDLGLEYR KLGWQSVLGS SGTIKTVAQV IATNLDPNGT ITAERLNALI 250
    EQTLQAKHFT ELNINGLNQD RVDVFVPGLA ILSAVFDVFH IQQMRYSDGA 300
    LREGVIYSLE KNFQVADIRA STA 323
    Length:323
    Mass (Da):35,566
    Last modified:November 1, 1995 - v1
    Checksum:i5B7E9BBEFE780FB6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22355.1.
    PIRiC64087.
    RefSeqiNP_438855.1. NC_000907.1.

    Genome annotation databases

    EnsemblBacteriaiAAC22355; AAC22355; HI_0695.
    GeneIDi950213.
    KEGGihin:HI0695.
    PATRICi20190011. VBIHaeInf48452_0727.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22355.1 .
    PIRi C64087.
    RefSeqi NP_438855.1. NC_000907.1.

    3D structure databases

    ProteinModelPortali P44828.
    SMRi P44828. Positions 16-321.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 71421.HI0695.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC22355 ; AAC22355 ; HI_0695 .
    GeneIDi 950213.
    KEGGi hin:HI0695.
    PATRICi 20190011. VBIHaeInf48452_0727.

    Phylogenomic databases

    eggNOGi COG0248.
    KOi K01524.
    OMAi AKHFTEL.
    OrthoDBi EOG6M6JN6.
    PhylomeDBi P44828.

    Family and domain databases

    InterProi IPR022371. Exopolyphosphatase.
    IPR003695. Ppx_GppA.
    [Graphical view ]
    Pfami PF02541. Ppx-GppA. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR03706. exo_poly_only. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

    Entry informationi

    Entry nameiPPX_HAEIN
    AccessioniPrimary (citable) accession number: P44828
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 89 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Caution

    Could be the product of a pseudogene. Compared with other ppx it lacks 200 residues at the C-terminal region.Curated

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Haemophilus influenzae
      Haemophilus influenzae (strain Rd): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3