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Protein

Probable lysophospholipase L2

Gene

pldB

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.

GO - Molecular functioni

  1. lysophospholipase activity Source: UniProtKB-EC

GO - Biological processi

  1. lipid metabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Probable lysophospholipase L2 (EC:3.1.1.5)
Alternative name(s):
Lecithinase B
Gene namesi
Name:pldB
Ordered Locus Names:HI_0645
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579 Componenti: Chromosome

Subcellular locationi

  1. Cell inner membrane By similarity

GO - Cellular componenti

  1. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 313313Probable lysophospholipase L2PRO_0000058457Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0645.

Structurei

3D structure databases

ProteinModelPortaliP44800.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG2267.
KOiK01048.
OMAiYHWVREG.
OrthoDBiEOG6CCH34.
PhylomeDBiP44800.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000073. AB_hydrolase_1.
[Graphical view]
PfamiPF00561. Abhydrolase_1. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

P44800-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIREPYFHQF ALAELLPFFE QFPTQYLSGK RNIKLAYRHL IQPESAVRKL
60 70 80 90 100
MILVNGRAEN MLKWSELAYD FYHQGYDVLL FDHRGQGYSQ RIIPQKGHLD
110 120 130 140 150
EFRFYVDDMA KIIEKVTALF SYSTQHLLAH SMGALIATYY LANYDHHINK
160 170 180 190 200
AVLSSPFYGI LLKHPIRDEL IITLMNILGQ GERYVFGKGA YQQAHLEYNE
210 220 230 240 250
LTFCKTRMKW MNRINRKNPA INLGGPTFRW VHLCLNAIKR LPKVIPKIEI
260 270 280 290 300
PILILQAEKE KIVDNKNLEK LTALFPNARC EVILNAKHEV LFEKDNVRRN
310
VLKSVNHFLN VQS
Length:313
Mass (Da):36,658
Last modified:November 1, 1995 - v1
Checksum:i891E784FF7F77C2E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22305.1.
PIRiA64084.
RefSeqiNP_438805.1. NC_000907.1.
WP_005694498.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22305; AAC22305; HI_0645.
GeneIDi949694.
KEGGihin:HI0645.
PATRICi20189905. VBIHaeInf48452_0674.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22305.1.
PIRiA64084.
RefSeqiNP_438805.1. NC_000907.1.
WP_005694498.1. NC_000907.1.

3D structure databases

ProteinModelPortaliP44800.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi71421.HI0645.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC22305; AAC22305; HI_0645.
GeneIDi949694.
KEGGihin:HI0645.
PATRICi20189905. VBIHaeInf48452_0674.

Phylogenomic databases

eggNOGiCOG2267.
KOiK01048.
OMAiYHWVREG.
OrthoDBiEOG6CCH34.
PhylomeDBiP44800.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000073. AB_hydrolase_1.
[Graphical view]
PfamiPF00561. Abhydrolase_1. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiPLDB_HAEIN
AccessioniPrimary (citable) accession number: P44800
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: February 4, 2015
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.