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P44785

- METN_HAEIN

UniProt

P44785 - METN_HAEIN

Protein

Methionine import ATP-binding protein MetN

Gene

metN

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 109 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi38 – 458ATPUniRule annotation

    GO - Molecular functioni

    1. amino acid-transporting ATPase activity Source: UniProtKB-HAMAP
    2. ATP binding Source: UniProtKB-HAMAP
    3. D-methionine transmembrane transporter activity Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Amino-acid transport, Transport

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Methionine import ATP-binding protein MetNUniRule annotation (EC:3.6.3.-UniRule annotation)
    Gene namesi
    Name:metNUniRule annotation
    Ordered Locus Names:HI_0621
    OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
    Taxonomic identifieri71421 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000000579: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

    GO - Cellular componenti

    1. ATP-binding cassette (ABC) transporter complex Source: UniProtKB-HAMAP
    2. Gram-negative-bacterium-type cell wall Source: InterPro

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 345345Methionine import ATP-binding protein MetNPRO_0000092509Add
    BLAST

    Interactioni

    Subunit structurei

    The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ).UniRule annotation

    Protein-protein interaction databases

    STRINGi71421.HI0621.

    Structurei

    3D structure databases

    ProteinModelPortaliP44785.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini2 – 241240ABC transporterUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. [View classification]UniRule annotation
    Contains 1 ABC transporter domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1135.
    KOiK02071.
    OMAiKMIQIKN.
    OrthoDBiEOG6T7N3V.
    PhylomeDBiP44785.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR003593. AAA+_ATPase.
    IPR026253. ABC_MetN.
    IPR012692. ABC_MetN_proteobac.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR017908. ABC_transprt_methionine_MetN_C.
    IPR018449. NIL_domain.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PANTHERiPTHR24220:SF186. PTHR24220:SF186. 1 hit.
    PfamiPF00005. ABC_tran. 1 hit.
    PF09383. NIL. 1 hit.
    [Graphical view]
    SMARTiSM00382. AAA. 1 hit.
    SM00930. NIL. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR02314. ABC_MetN. 1 hit.
    PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 1 hit.
    PS51264. METN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P44785-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIKLNNIXKI FELPXKKLTA LDNVSLNIEK GQICGVIGAS GAGKSTLIRC    50
    VNLLEKPTSG SVIVDGVELT KLSDRELVLA RRQIGMIFQH FNLLSSRTVF 100
    ENVALPLELE SESKAKIQEK ITALLDLVGL SEKRDAYPSN LSGGQKQRVA 150
    IARALASDPK VLLCDEATSA LDPATTQSIL KLLKEINRTL GITILLITHE 200
    MEVVKQICDQ VAVIDQGRLV EQGTVGEIFA NPKTELAQEF IRSTFHISLP 250
    DEYLENLTDT PKHSKAYPII KFEFTGRSVD APLLSQASKK FGVELSILTS 300
    QIDYAGGVKF GYTIAEVEGD EDAITQTKVY LMENNVRVEV LGYVQ 345
    Length:345
    Mass (Da):37,880
    Last modified:November 1, 1995 - v1
    Checksum:i7457118E8BEB79C2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22280.1.
    PIRiC64082.
    RefSeqiNP_438780.1. NC_000907.1.

    Genome annotation databases

    EnsemblBacteriaiAAC22280; AAC22280; HI_0621.
    GeneIDi950557.
    KEGGihin:HI0621.
    PATRICi20189827. VBIHaeInf48452_0646.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22280.1 .
    PIRi C64082.
    RefSeqi NP_438780.1. NC_000907.1.

    3D structure databases

    ProteinModelPortali P44785.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 71421.HI0621.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC22280 ; AAC22280 ; HI_0621 .
    GeneIDi 950557.
    KEGGi hin:HI0621.
    PATRICi 20189827. VBIHaeInf48452_0646.

    Phylogenomic databases

    eggNOGi COG1135.
    KOi K02071.
    OMAi KMIQIKN.
    OrthoDBi EOG6T7N3V.
    PhylomeDBi P44785.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR003593. AAA+_ATPase.
    IPR026253. ABC_MetN.
    IPR012692. ABC_MetN_proteobac.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR017908. ABC_transprt_methionine_MetN_C.
    IPR018449. NIL_domain.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    PANTHERi PTHR24220:SF186. PTHR24220:SF186. 1 hit.
    Pfami PF00005. ABC_tran. 1 hit.
    PF09383. NIL. 1 hit.
    [Graphical view ]
    SMARTi SM00382. AAA. 1 hit.
    SM00930. NIL. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR02314. ABC_MetN. 1 hit.
    PROSITEi PS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 1 hit.
    PS51264. METN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

    Entry informationi

    Entry nameiMETN_HAEIN
    AccessioniPrimary (citable) accession number: P44785
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 109 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Haemophilus influenzae
      Haemophilus influenzae (strain Rd): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3