Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P44777 (FUCA_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
L-fuculose phosphate aldolase

EC=4.1.2.17
Alternative name(s):
L-fuculose-1-phosphate aldolase
Gene names
Name:fucA
Ordered Locus Names:HI_0611
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length216 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the cleavage of L-fuculose 1-phosphate to glycerone phosphate and L-lactaldehyde By similarity. HAMAP-Rule MF_00987

Catalytic activity

L-fuculose 1-phosphate = glycerone phosphate + (S)-lactaldehyde. HAMAP-Rule MF_00987

Cofactor

Binds 1 zinc ion per subunit Potential.

Pathway

Carbohydrate degradation; L-fucose degradation; L-lactaldehyde and glycerone phosphate from L-fucose: step 3/3. HAMAP-Rule MF_00987

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00987

Sequence similarities

Belongs to the aldolase class II family. AraD/FucA subfamily.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Fucose metabolism
   LigandMetal-binding
Zinc
   Molecular functionLyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processfucose catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionL-fuculose-phosphate aldolase activity

Inferred from electronic annotation. Source: UniProtKB-EC

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 216216L-fuculose phosphate aldolase HAMAP-Rule MF_00987
PRO_0000162928

Sites

Active site731Proton acceptor By similarity
Active site1131Proton donor By similarity
Metal binding731Zinc By similarity
Metal binding921Zinc By similarity
Metal binding941Zinc By similarity
Metal binding1551Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
P44777 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 4DBEEE21ED8EA6C6

FASTA21623,944
        10         20         30         40         50         60 
MNRAELSQKI IDTCLEMTKL GLNQGTAGNV SVRYKDGMLI TPTGMPYHLM KTENIVYVDG 

        70         80         90        100        110        120 
NGKHEENKLP SSEWQFHLSV YHTRPEANAV VHNHSIHCAG LSILEKPIPA IHYMVAVSGT 

       130        140        150        160        170        180 
DHIPCVPYAT FGSHKLASYV ATGIKESKAI LLAHHGLITC GENLDKALWL AQEVEVLASW 

       190        200        210 
YLKLLSTGLE IPLLSKEQMQ VVLGKFHTYG LRIEES 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L42023 Genomic DNA. Translation: AAC22270.1.
PIRC64081.
RefSeqNP_438769.1. NC_000907.1.

3D structure databases

ProteinModelPortalP44777.
SMRP44777. Positions 1-210.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING71421.HI0611.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC22270; AAC22270; HI_0611.
GeneID950000.
KEGGhin:HI0611.
PATRIC20189805. VBIHaeInf48452_0635.

Phylogenomic databases

eggNOGCOG0235.
KOK01628.
OMAYATFGTH.
OrthoDBEOG6HQSSQ.
PhylomeDBP44777.

Enzyme and pathway databases

UniPathwayUPA00563; UER00626.

Family and domain databases

Gene3D3.40.225.10. 1 hit.
HAMAPMF_00987. FucA.
InterProIPR001303. Aldolase_II/adducin_N.
IPR004782. FucA.
[Graphical view]
PfamPF00596. Aldolase_II. 1 hit.
[Graphical view]
SMARTSM01007. Aldolase_II. 1 hit.
[Graphical view]
SUPFAMSSF53639. SSF53639. 1 hit.
TIGRFAMsTIGR01086. fucA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameFUCA_HAEIN
AccessionPrimary (citable) accession number: P44777
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: July 9, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names