Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P44777

- FUCA_HAEIN

UniProt

P44777 - FUCA_HAEIN

Protein

L-fuculose phosphate aldolase

Gene

fucA

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 93 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the cleavage of L-fuculose 1-phosphate to glycerone phosphate and L-lactaldehyde.UniRule annotation

    Catalytic activityi

    L-fuculose 1-phosphate = glycerone phosphate + (S)-lactaldehyde.UniRule annotation

    Cofactori

    Binds 1 zinc ion per subunit.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei73 – 731Proton acceptorUniRule annotation
    Metal bindingi73 – 731ZincUniRule annotation
    Metal bindingi92 – 921ZincUniRule annotation
    Metal bindingi94 – 941ZincUniRule annotation
    Active sitei113 – 1131Proton donorUniRule annotation
    Metal bindingi155 – 1551ZincUniRule annotation

    GO - Molecular functioni

    1. L-fuculose-phosphate aldolase activity Source: UniProtKB-EC
    2. zinc ion binding Source: InterPro

    GO - Biological processi

    1. fucose catabolic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Carbohydrate metabolism, Fucose metabolism

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    UniPathwayiUPA00563; UER00626.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    L-fuculose phosphate aldolaseUniRule annotation (EC:4.1.2.17UniRule annotation)
    Alternative name(s):
    L-fuculose-1-phosphate aldolaseUniRule annotation
    Gene namesi
    Name:fucAUniRule annotation
    Ordered Locus Names:HI_0611
    OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
    Taxonomic identifieri71421 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000000579: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 216216L-fuculose phosphate aldolasePRO_0000162928Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi71421.HI0611.

    Structurei

    3D structure databases

    ProteinModelPortaliP44777.
    SMRiP44777. Positions 1-210.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the aldolase class II family. AraD/FucA subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0235.
    KOiK01628.
    OMAiYATFGTH.
    OrthoDBiEOG6HQSSQ.
    PhylomeDBiP44777.

    Family and domain databases

    Gene3Di3.40.225.10. 1 hit.
    HAMAPiMF_00987. FucA.
    InterProiIPR001303. Aldolase_II/adducin_N.
    IPR004782. FucA.
    [Graphical view]
    PfamiPF00596. Aldolase_II. 1 hit.
    [Graphical view]
    SMARTiSM01007. Aldolase_II. 1 hit.
    [Graphical view]
    SUPFAMiSSF53639. SSF53639. 1 hit.
    TIGRFAMsiTIGR01086. fucA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P44777-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNRAELSQKI IDTCLEMTKL GLNQGTAGNV SVRYKDGMLI TPTGMPYHLM    50
    KTENIVYVDG NGKHEENKLP SSEWQFHLSV YHTRPEANAV VHNHSIHCAG 100
    LSILEKPIPA IHYMVAVSGT DHIPCVPYAT FGSHKLASYV ATGIKESKAI 150
    LLAHHGLITC GENLDKALWL AQEVEVLASW YLKLLSTGLE IPLLSKEQMQ 200
    VVLGKFHTYG LRIEES 216
    Length:216
    Mass (Da):23,944
    Last modified:November 1, 1995 - v1
    Checksum:i4DBEEE21ED8EA6C6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22270.1.
    PIRiC64081.
    RefSeqiNP_438769.1. NC_000907.1.

    Genome annotation databases

    EnsemblBacteriaiAAC22270; AAC22270; HI_0611.
    GeneIDi950000.
    KEGGihin:HI0611.
    PATRICi20189805. VBIHaeInf48452_0635.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22270.1 .
    PIRi C64081.
    RefSeqi NP_438769.1. NC_000907.1.

    3D structure databases

    ProteinModelPortali P44777.
    SMRi P44777. Positions 1-210.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 71421.HI0611.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC22270 ; AAC22270 ; HI_0611 .
    GeneIDi 950000.
    KEGGi hin:HI0611.
    PATRICi 20189805. VBIHaeInf48452_0635.

    Phylogenomic databases

    eggNOGi COG0235.
    KOi K01628.
    OMAi YATFGTH.
    OrthoDBi EOG6HQSSQ.
    PhylomeDBi P44777.

    Enzyme and pathway databases

    UniPathwayi UPA00563 ; UER00626 .

    Family and domain databases

    Gene3Di 3.40.225.10. 1 hit.
    HAMAPi MF_00987. FucA.
    InterProi IPR001303. Aldolase_II/adducin_N.
    IPR004782. FucA.
    [Graphical view ]
    Pfami PF00596. Aldolase_II. 1 hit.
    [Graphical view ]
    SMARTi SM01007. Aldolase_II. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53639. SSF53639. 1 hit.
    TIGRFAMsi TIGR01086. fucA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

    Entry informationi

    Entry nameiFUCA_HAEIN
    AccessioniPrimary (citable) accession number: P44777
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 93 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Haemophilus influenzae
      Haemophilus influenzae (strain Rd): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3