P44721 (SURA_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative peptidyl-prolyl cis-trans isomerase SurA
Short name=PPIase SurA
EC=5.2.1.8

Alternative name(s):
Chaperone SurA homolog
Rotamase SurA

Gene names

Name:	surA
Ordered Locus Names:	HI_0458

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus influenzae

Protein attributes

Sequence length	313 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Chaperone involved in the folding of extracytoplasmic proteins By similarity.
Catalytic activity	Peptidylproline (omega=180) = peptidylproline (omega=0).
Subcellular location	Periplasm Potential.
Sequence similarities	Contains 1 PpiC domain.

Ontologies

Keywords
Cellular component	Periplasm
Domain	Signal
Molecular function	Chaperone Isomerase Rotamase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	protein folding Inferred from electronic annotation. Source: UniProtKB-KW protein peptidyl-prolyl isomerization Inferred from electronic annotation. Source: GOC
Cellular_component	periplasmic space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	peptidyl-prolyl cis-trans isomerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 27	27	Potential
	Chain	28 – 313	286	Putative peptidyl-prolyl cis-trans isomerase SurA		PRO_0000025543
Regions
	Domain	167 – 267	101	PpiC

Sequences

	Sequence		Length	Mass (Da)
	P44721 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: EAE2A7C352302450	FASTA	313	34,670
	10 20 30 40 50 60 MKMKKFVLRS FLLATLGCVA FTSMAQAEER VVATVDGIPV LESQVRANMG KKGDRQSAID 70 80 90 100 110 120 KIIDDILVQK AVQESGVKID PREIDHIVED TAARNGLTYG QFLDALDYQG ISLNTFRQQI 130 140 150 160 170 180 ANQMVMGAVR NKAIQESIDV TREEVVALGQ KMLDEAKSQG TAQKVTGKEY EVRHILLKLN 190 200 210 220 230 240 PLLNDAQAKK QLAKIRSDII AGKTTFADAA LKYSKDYLSG ANGGSLGYAF PETYAPQFAQ 250 260 270 280 290 300 TVVKSKQGVI SAPFKTEFGW HILEVTGVRD GDLTAEAYTQ KAYERLVNTQ LQDATNDWVK 310 ALRKRANIQY FNK

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC22116.1.
PIR	F64069.
RefSeq	NP_438619.1. NC_000907.1.
3D structure databases
ProteinModelPortal	P44721.
ModBase	Search...
Protein-protein interaction databases
STRING	71421.HI0458.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC22116; AAC22116; HI_0458.
GeneID	949829.
KEGG	hin:HI0458.
PATRIC	20189471. VBIHaeInf48452_0478.
Phylogenomic databases
eggNOG	COG0760.
KO	K03771.
OMA	MAQAEER.
ProtClustDB	CLSK870395.
Family and domain databases
InterPro	IPR000297. PPIase_PpiC. IPR023058. PPIase_PpiC_CS. IPR015391. SurA_N. IPR027304. Trigger_fact/SurA_dom. [Graphical view]
Pfam	PF00639. Rotamase. 1 hit. PF09312. SurA_N. 1 hit. [Graphical view]
SUPFAM	SSF109998. Trigger_fac_C_bac. 1 hit.
PROSITE	PS01096. PPIC_PPIASE_1. 1 hit. PS50198. PPIC_PPIASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SURA_HAEIN

Accession

Primary (citable) accession number: P44721

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	May 1, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program