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Protein

Ribosome-binding ATPase YchF

Gene

ychF

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner (By similarity). Does not hydrolyze GTP.UniRule annotation1 Publication

Cofactori

Mg2+By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi16MagnesiumBy similarity1
Metal bindingi36MagnesiumBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi12 – 17ATPUniRule annotation6

GO - Molecular functioni

Keywordsi

LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHINF71421:G1GJ1-408-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosome-binding ATPase YchFUniRule annotation
Gene namesi
Name:ychFUniRule annotation
Synonyms:engD
Ordered Locus Names:HI_0393
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000000579 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00002016782 – 363Ribosome-binding ATPase YchFAdd BLAST362

Proteomic databases

PRIDEiP44681

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0393

Structurei

Secondary structure

1363
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi4 – 8Combined sources5
Helixi15 – 24Combined sources10
Beta strandi41 – 45Combined sources5
Helixi49 – 58Combined sources10
Beta strandi61 – 64Combined sources4
Beta strandi67 – 72Combined sources6
Helixi80 – 83Combined sources4
Helixi84 – 86Combined sources3
Helixi90 – 95Combined sources6
Beta strandi98 – 105Combined sources8
Helixi121 – 151Combined sources31
Turni152 – 154Combined sources3
Helixi156 – 173Combined sources18
Helixi178 – 180Combined sources3
Helixi185 – 191Combined sources7
Helixi192 – 194Combined sources3
Beta strandi202 – 207Combined sources6
Beta strandi213 – 215Combined sources3
Helixi217 – 228Combined sources12
Beta strandi232 – 236Combined sources5
Helixi238 – 243Combined sources6
Helixi244 – 246Combined sources3
Helixi253 – 256Combined sources4
Helixi267 – 276Combined sources10
Beta strandi279 – 285Combined sources7
Beta strandi287 – 296Combined sources10
Helixi301 – 306Combined sources6
Helixi312 – 315Combined sources4
Beta strandi318 – 322Combined sources5
Helixi324 – 329Combined sources6
Helixi333 – 338Combined sources6
Beta strandi343 – 345Combined sources3
Beta strandi356 – 361Combined sources6

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1JALX-ray2.40A/B1-363[»]
ProteinModelPortaliP44681
SMRiP44681
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP44681

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 256OBG-type GAdd BLAST254

Domaini

Composed of 3 distinct structural domains: the N-terminal domain, which has a mononucleotide binding fold typical for the P-loop NTPases, followed by a pronounced alpha-helical coiled coil domain and the C-terminal domain, which may be involved in RNA binding.1 Publication

Sequence similaritiesi

Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C3G Bacteria
COG0012 LUCA
KOiK06942
OMAiHKDFEKG
PhylomeDBiP44681

Family and domain databases

Gene3Di1.10.150.300, 1 hit
3.10.20.30, 2 hits
HAMAPiMF_00944 YchF_OLA1_ATPase, 1 hit
InterProiView protein in InterPro
IPR004396 ATPase_YchF/OLA1
IPR012675 Beta-grasp_dom_sf
IPR031167 G_OBG
IPR006073 GTP_binding_domain
IPR027417 P-loop_NTPase
IPR012676 TGS-like
IPR023192 TGS-like_dom_sf
IPR013029 YchF_C
PfamiView protein in Pfam
PF01926 MMR_HSR1, 1 hit
PF06071 YchF-GTPase_C, 1 hit
PIRSFiPIRSF006641 CHP00092, 1 hit
PRINTSiPR00326 GTP1OBG
SUPFAMiSSF52540 SSF52540, 1 hit
SSF81271 SSF81271, 1 hit
TIGRFAMsiTIGR00092 TIGR00092, 1 hit
PROSITEiView protein in PROSITE
PS51710 G_OBG, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P44681-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGFKCGIVGL PNVGKSTLFN ALTKAGIEAA NYPFCTIEPN TGVVPMPDPR
60 70 80 90 100
LDALAEIVKP ERILPTTMEF VDIAGLVAGA SKGEGLGNKF LANIRETDAI
110 120 130 140 150
GHVVRCFEND DIVHVAGKID PLDDIDTINT ELALADLDSC ERAIQRLQKR
160 170 180 190 200
AKGGDKEAKF ELSVMEKILP VLENAGMIRS VGLDKEELQA IKSYNFLTLK
210 220 230 240 250
PTMYIANVNE DGFENNPYLD RVREIAAKEG AVVVPVCAAI ESEIAELDDE
260 270 280 290 300
EKVEFLQDLG IEEPGLNRVI RAGYALLNLQ TYFTAGVKEV RAWTVSVGAT
310 320 330 340 350
APKAAAVIHT DFEKGFIRAE VIAYEDFIQF NGENGAKEAG KWRLEGKDYI
360
VQDGDVMHFR FNV
Length:363
Mass (Da):39,751
Last modified:January 23, 2007 - v2
Checksum:i08E00CBEF7D0F65E
GO

Mass spectrometryi

Molecular mass is 40011 Da from positions 2 - 363. Determined by MALDI. 1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA Translation: AAC22052.1
PIRiI64150
RefSeqiNP_438555.1, NC_000907.1
WP_005693776.1, NC_000907.1

Genome annotation databases

EnsemblBacteriaiAAC22052; AAC22052; HI_0393
GeneIDi949492
KEGGihin:HI0393
PATRICifig|71421.8.peg.412

Similar proteinsi

Entry informationi

Entry nameiYCHF_HAEIN
AccessioniPrimary (citable) accession number: P44681
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 133 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

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