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P44680

- Y387_HAEIN

UniProt

P44680 - Y387_HAEIN

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Protein

Probable ATP-dependent helicase HI_0387

Gene
HI_0387
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi51 – 588ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. ATP-dependent helicase activity Source: InterPro
  3. DNA binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Helicase, Hydrolase

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable ATP-dependent helicase HI_0387 (EC:3.6.4.12)
Gene namesi
Ordered Locus Names:HI_0387
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 640640Probable ATP-dependent helicase HI_0387PRO_0000102007Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0387.

Structurei

3D structure databases

ProteinModelPortaliP44680.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini16 – 278263Helicase ATP-bindingAdd
BLAST
Domaini458 – 634177Helicase C-terminalAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi231 – 2344DEAH box

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1199.
KOiK03722.
OMAiICDSRLV.
OrthoDBiEOG6742WF.
PhylomeDBiP44680.

Family and domain databases

Gene3Di3.40.50.300. 3 hits.
InterProiIPR006555. ATP-dep_Helicase_C.
IPR014013. Helic_SF1/SF2_ATP-bd_DinG/Rad3.
IPR006935. Helicase/UvrB_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF13307. Helicase_C_2. 1 hit.
PF04851. ResIII. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00491. HELICc2. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 4 hits.
PROSITEiPS51193. HELICASE_ATP_BIND_2. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P44680-1 [UniParc]FASTAAdd to Basket

« Hide

MDYENQIANI FSLNGELSQN IKGFRPRAEQ LEMAYAVGKA IQNKSSLVIE    50
AGTGTGKTFA YLAPALVFGK KTIISTGSKN LQDQLFNRDL PAIKKALNFT 100
GKIALLKGRA NYLCLERLDQ VIAQGVLGDK SVLAELSKVR KWNNSTKTGD 150
FTECIELAED SPIIPQLTST AESCLGTDCP NYSECYVASA RKKALNADLV 200
VVNHHLFFAD MAVKESGFGE LIPNAEVIIF DEAHQLPDIA SQYFGQSLTS 250
RQLFDLCKDI NIVYRTELKD MQQLGTTSDT LLKVVQDFRL LLGNGSNVRG 300
NWRELYTQSA VKKAFELLQE KIDFLSEVIK LALGRSQTLD SIFERVESIK 350
IQLKRLSETN IVGYCYWYEG NGRQFGLHIT PLTVADKFGA QLEAKEAAWI 400
FTSATLEVGG TFNHFCQRLG IENATQKILY SPFNYPEQSL LCVPRYLPNT 450
NQMNTLNSLG EILLPVIEAN KGRCFVLCTS YSMMRGLAEY FREKSHLSIL 500
LQGETSKGKL LEQFIKETHS VLVATSSFWE GVDVRGDALS LVIIDKLPFT 550
APDEPLLKAR IEDCRLQGGD PFNDIQIPEA VITLKQGVGR LIRDVTDRGV 600
VIICDNRLVM RNYGETFLKS LPNSSRTRDL NKVIQFLQNK 640
Length:640
Mass (Da):71,531
Last modified:November 1, 1995 - v1
Checksum:iEC659D19C2F23D3C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC22045.1.
PIRiA64065.
RefSeqiNP_438548.1. NC_000907.1.
WP_005693783.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22045; AAC22045; HI_0387.
GeneIDi949750.
KEGGihin:HI0387.
PATRICi20189323. VBIHaeInf48452_0405.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC22045.1 .
PIRi A64065.
RefSeqi NP_438548.1. NC_000907.1.
WP_005693783.1. NC_000907.1.

3D structure databases

ProteinModelPortali P44680.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 71421.HI0387.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC22045 ; AAC22045 ; HI_0387 .
GeneIDi 949750.
KEGGi hin:HI0387.
PATRICi 20189323. VBIHaeInf48452_0405.

Phylogenomic databases

eggNOGi COG1199.
KOi K03722.
OMAi ICDSRLV.
OrthoDBi EOG6742WF.
PhylomeDBi P44680.

Family and domain databases

Gene3Di 3.40.50.300. 3 hits.
InterProi IPR006555. ATP-dep_Helicase_C.
IPR014013. Helic_SF1/SF2_ATP-bd_DinG/Rad3.
IPR006935. Helicase/UvrB_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF13307. Helicase_C_2. 1 hit.
PF04851. ResIII. 1 hit.
[Graphical view ]
SMARTi SM00487. DEXDc. 1 hit.
SM00491. HELICc2. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 4 hits.
PROSITEi PS51193. HELICASE_ATP_BIND_2. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiY387_HAEIN
AccessioniPrimary (citable) accession number: P44680
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: September 3, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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