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P44680

- Y387_HAEIN

UniProt

P44680 - Y387_HAEIN

Protein

Probable ATP-dependent helicase HI_0387

Gene

HI_0387

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 97 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + H2O = ADP + phosphate.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi51 – 588ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. ATP-dependent helicase activity Source: InterPro
    3. DNA binding Source: UniProtKB-KW

    Keywords - Molecular functioni

    Helicase, Hydrolase

    Keywords - Ligandi

    ATP-binding, DNA-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable ATP-dependent helicase HI_0387 (EC:3.6.4.12)
    Gene namesi
    Ordered Locus Names:HI_0387
    OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
    Taxonomic identifieri71421 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000000579: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 640640Probable ATP-dependent helicase HI_0387PRO_0000102007Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi71421.HI0387.

    Structurei

    3D structure databases

    ProteinModelPortaliP44680.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini16 – 278263Helicase ATP-bindingPROSITE-ProRule annotationAdd
    BLAST
    Domaini458 – 634177Helicase C-terminalPROSITE-ProRule annotationAdd
    BLAST

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi231 – 2344DEAH box

    Sequence similaritiesi

    Belongs to the helicase family. DinG subfamily.Curated
    Contains 1 helicase ATP-binding domain.PROSITE-ProRule annotation
    Contains 1 helicase C-terminal domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG1199.
    KOiK03722.
    OMAiICDSRLV.
    OrthoDBiEOG6742WF.
    PhylomeDBiP44680.

    Family and domain databases

    Gene3Di3.40.50.300. 3 hits.
    InterProiIPR006555. ATP-dep_Helicase_C.
    IPR014013. Helic_SF1/SF2_ATP-bd_DinG/Rad3.
    IPR006935. Helicase/UvrB_dom.
    IPR014001. Helicase_ATP-bd.
    IPR001650. Helicase_C.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF13307. Helicase_C_2. 1 hit.
    PF04851. ResIII. 1 hit.
    [Graphical view]
    SMARTiSM00487. DEXDc. 1 hit.
    SM00491. HELICc2. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 4 hits.
    PROSITEiPS51193. HELICASE_ATP_BIND_2. 1 hit.
    PS51194. HELICASE_CTER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P44680-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDYENQIANI FSLNGELSQN IKGFRPRAEQ LEMAYAVGKA IQNKSSLVIE    50
    AGTGTGKTFA YLAPALVFGK KTIISTGSKN LQDQLFNRDL PAIKKALNFT 100
    GKIALLKGRA NYLCLERLDQ VIAQGVLGDK SVLAELSKVR KWNNSTKTGD 150
    FTECIELAED SPIIPQLTST AESCLGTDCP NYSECYVASA RKKALNADLV 200
    VVNHHLFFAD MAVKESGFGE LIPNAEVIIF DEAHQLPDIA SQYFGQSLTS 250
    RQLFDLCKDI NIVYRTELKD MQQLGTTSDT LLKVVQDFRL LLGNGSNVRG 300
    NWRELYTQSA VKKAFELLQE KIDFLSEVIK LALGRSQTLD SIFERVESIK 350
    IQLKRLSETN IVGYCYWYEG NGRQFGLHIT PLTVADKFGA QLEAKEAAWI 400
    FTSATLEVGG TFNHFCQRLG IENATQKILY SPFNYPEQSL LCVPRYLPNT 450
    NQMNTLNSLG EILLPVIEAN KGRCFVLCTS YSMMRGLAEY FREKSHLSIL 500
    LQGETSKGKL LEQFIKETHS VLVATSSFWE GVDVRGDALS LVIIDKLPFT 550
    APDEPLLKAR IEDCRLQGGD PFNDIQIPEA VITLKQGVGR LIRDVTDRGV 600
    VIICDNRLVM RNYGETFLKS LPNSSRTRDL NKVIQFLQNK 640
    Length:640
    Mass (Da):71,531
    Last modified:November 1, 1995 - v1
    Checksum:iEC659D19C2F23D3C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22045.1.
    PIRiA64065.
    RefSeqiNP_438548.1. NC_000907.1.
    WP_005693783.1. NC_000907.1.

    Genome annotation databases

    EnsemblBacteriaiAAC22045; AAC22045; HI_0387.
    GeneIDi949750.
    KEGGihin:HI0387.
    PATRICi20189323. VBIHaeInf48452_0405.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22045.1 .
    PIRi A64065.
    RefSeqi NP_438548.1. NC_000907.1.
    WP_005693783.1. NC_000907.1.

    3D structure databases

    ProteinModelPortali P44680.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 71421.HI0387.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC22045 ; AAC22045 ; HI_0387 .
    GeneIDi 949750.
    KEGGi hin:HI0387.
    PATRICi 20189323. VBIHaeInf48452_0405.

    Phylogenomic databases

    eggNOGi COG1199.
    KOi K03722.
    OMAi ICDSRLV.
    OrthoDBi EOG6742WF.
    PhylomeDBi P44680.

    Family and domain databases

    Gene3Di 3.40.50.300. 3 hits.
    InterProi IPR006555. ATP-dep_Helicase_C.
    IPR014013. Helic_SF1/SF2_ATP-bd_DinG/Rad3.
    IPR006935. Helicase/UvrB_dom.
    IPR014001. Helicase_ATP-bd.
    IPR001650. Helicase_C.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF13307. Helicase_C_2. 1 hit.
    PF04851. ResIII. 1 hit.
    [Graphical view ]
    SMARTi SM00487. DEXDc. 1 hit.
    SM00491. HELICc2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 4 hits.
    PROSITEi PS51193. HELICASE_ATP_BIND_2. 1 hit.
    PS51194. HELICASE_CTER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

    Entry informationi

    Entry nameiY387_HAEIN
    AccessioniPrimary (citable) accession number: P44680
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 97 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Haemophilus influenzae
      Haemophilus influenzae (strain Rd): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3