P44680 (Y387_HAEIN) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 88.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Probable ATP-dependent helicase HI_0387 EC=3.6.4.12 | ||
| Gene names |
| ||
| Organism | Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP] | ||
| Taxonomic identifier | 71421 [NCBI] | ||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › ![]() |
Protein attributes
| Sequence length | 640 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | ATP + H2O = ADP + phosphate. |
| Sequence similarities | Belongs to the helicase family. DinG subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. |
Ontologies
| Keywords | |
|---|---|
| Ligand | ATP-binding DNA-binding Nucleotide-binding |
| Molecular function | Helicase Hydrolase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Molecular_function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATP-dependent helicase activityInferred from electronic annotation. Source: InterPro DNA bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 640 | 640 | Probable ATP-dependent helicase HI_0387 | PRO_0000102007 | |||||
Regions | |||||||||
| Domain | 16 – 278 | 263 | Helicase ATP-binding | ||||||
| Domain | 458 – 634 | 177 | Helicase C-terminal | ||||||
| Nucleotide binding | 51 – 58 | 8 | ATP Potential | ||||||
| Motif | 231 – 234 | 4 | DEAH box | ||||||
Sequences
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References
| [1] | "Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. Venter J.C.Science 269:496-512(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | L42023 Genomic DNA. Translation: AAC22045.1. |
| PIR | A64065. |
| RefSeq | NP_438548.1. NC_000907.1. |
3D structure databases | |
| ProteinModelPortal | P44680. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 71421.HI0387. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | AAC22045; AAC22045; HI_0387. |
| GeneID | 949750. |
| KEGG | hin:HI0387. |
| PATRIC | 20189323. VBIHaeInf48452_0405. |
Phylogenomic databases | |
| eggNOG | COG1199. |
| KO | K03722. |
| OMA | QFGLHIT. |
| ProtClustDB | CLSK870213. |
Family and domain databases | |
| InterPro | IPR006555. ATP-dep_Helicase_C. IPR014013. Helic_SF1/SF2_ATP-bd_DinG/Rad3. IPR006935. Helicase/UvrB_dom. IPR014001. Helicase_ATP-bd. IPR001650. Helicase_C. [Graphical view] |
| Pfam | PF13307. Helicase_C_2. 1 hit. PF04851. ResIII. 1 hit. [Graphical view] |
| SMART | SM00487. DEXDc. 1 hit. SM00491. HELICc2. 1 hit. [Graphical view] |
| PROSITE | PS00690. DEAH_ATP_HELICASE. False negative. PS51193. HELICASE_ATP_BIND_2. 1 hit. PS51194. HELICASE_CTER. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | Y387_HAEIN | ||||||||
| Accession | Primary (citable) accession number: P44680 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Haemophilus influenzae Haemophilus influenzae (strain Rd): entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with
