P44662 (Y361_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable iron transport system ATP-binding protein HI_0361

Gene names

Ordered Locus Names:

HI_0361

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus influenzae

Protein attributes

Sequence length	306 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of an ATP-driven transport system HI_0359/HI_0360/HI_0361/HI_0362 for iron. Probably responsible for energy coupling to the transport system.
Subcellular location	Cell inner membrane; Peripheral membrane protein Potential.
Sequence similarities	Belongs to the ABC transporter superfamily. Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Ion transport Iron transport Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Ligand	ATP-binding Iron Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from electronic annotation. Source: GOC ion transport Inferred from electronic annotation. Source: UniProtKB-KW iron ion homeostasis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 306	306	Probable iron transport system ATP-binding protein HI_0361		PRO_0000093200
Regions
	Domain	8 – 243	236	ABC transporter
	Nucleotide binding	41 – 48	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	P44662 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 8A725B71E52C6C70	FASTA	306	34,251
	10 20 30 40 50 60 MDSFSTSIWV NDVTVRYNNG HTAIHNMTFS LNSGTICALV GVNGSGKSTL FKSIMGLVKP 70 80 90 100 110 120 QQGEIKLCDL PISQALKRNL VAYVPQSEEV DWQFPVSVYD VVMMGRYGYM NFLRIPKAID 130 140 150 160 170 180 KQKVQEAMQR VNIEHLAHRQ IGELSGGQKK RVFLARALAQ QSPIILLDEP FTGVDVKTEN 190 200 210 220 230 240 AIVDLLQQLR EEGHLILVST HNLGSVPDFC DQVVMINRTV IAAGKTEDTF NQHNLEIVFG 250 260 270 280 290 300 GVLRHIKLLG ENLHNDEDKR SVTVLTDDEK AVVFYGETKQ DPPAPTTQNC HFEDCPYKSA VKNKRD

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC22020.1.
PIR	F64063.
RefSeq	NP_438523.1. NC_000907.1.
3D structure databases
ProteinModelPortal	P44662.
ModBase	Search...
Protein-protein interaction databases
STRING	71421.HI0361.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC22020; AAC22020; HI_0361.
GeneID	950559.
KEGG	hin:HI0361.
PATRIC	20189267. VBIHaeInf48452_0379.
Phylogenomic databases
eggNOG	COG1121.
KO	K11607.
OMA	AQEGQVI.
ProtClustDB	CLSK789426.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. [Graphical view]
Pfam	PF00005. ABC_tran. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y361_HAEIN

Accession

Primary (citable) accession number: P44662

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	May 1, 2013
This is version 91 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program