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Protein

Apolipoprotein N-acyltransferase

Gene

lnt

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transfers the fatty acyl group on membrane lipoproteins.By similarity

Pathwayi: lipoprotein biosynthesis (N-acyl transfer)

This protein is involved in the pathway lipoprotein biosynthesis (N-acyl transfer), which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway lipoprotein biosynthesis (N-acyl transfer) and in Protein modification.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei276Proton acceptorPROSITE-ProRule annotation1
Active sitei342PROSITE-ProRule annotation1
Active sitei394NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

UniPathwayiUPA00666

Names & Taxonomyi

Protein namesi
Recommended name:
Apolipoprotein N-acyltransferase (EC:2.3.1.-)
Short name:
ALP N-acyltransferase
Alternative name(s):
Copper homeostasis protein CutE homolog
Gene namesi
Name:lnt
Synonyms:cutE
Ordered Locus Names:HI_0302
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei17 – 37HelicalSequence analysisAdd BLAST21
Transmembranei61 – 81HelicalSequence analysisAdd BLAST21
Transmembranei98 – 118HelicalSequence analysisAdd BLAST21
Transmembranei164 – 184HelicalSequence analysisAdd BLAST21
Transmembranei197 – 217HelicalSequence analysisAdd BLAST21
Transmembranei495 – 515HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001780681 – 522Apolipoprotein N-acyltransferaseAdd BLAST522

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0302

Structurei

3D structure databases

ProteinModelPortaliP44626
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini236 – 483CN hydrolasePROSITE-ProRule annotationAdd BLAST248

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CE8 Bacteria
COG0815 LUCA
KOiK03820
OMAiPIGEFVP

Family and domain databases

CDDicd07571 ALP_N-acyl_transferase, 1 hit
Gene3Di3.60.110.10, 1 hit
HAMAPiMF_01148 Lnt, 1 hit
InterProiView protein in InterPro
IPR004563 Apolipo_AcylTrfase
IPR003010 C-N_Hydrolase
IPR036526 C-N_Hydrolase_sf
PfamiView protein in Pfam
PF00795 CN_hydrolase, 1 hit
SUPFAMiSSF56317 SSF56317, 1 hit
TIGRFAMsiTIGR00546 lnt, 1 hit
PROSITEiView protein in PROSITE
PS50263 CN_HYDROLASE, 1 hit

Sequencei

Sequence statusi: Complete.

P44626-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNLNRILLS IKFMNKYFTY LIAIISGLLG VFAFSPFDYW PLAYVSLLGL
60 70 80 90 100
LYVAKNPKKS TALLSTFLWA MGFFCFGVSW LNVSIHQFGG ASLGVSYFLV
110 120 130 140 150
GLLAAYLALY PMLFTYLVHH FKVQSAVIFA VIWTLTEFLR GWIFTGFPWL
160 170 180 190 200
QFGYTQIDSP FYGIAPIFGV TGLTFFTVWA SAVIFNLVSS LFKTKNLKLV
210 220 230 240 250
LANALLLIIV GGLSAYSSRI HFVKSVEDKA ISVTLAQGNI EQNLKWDPNY
260 270 280 290 300
FYSTLAIYQK LITENLGKTD LIILPESALP TLENAITPFF EGLERAAKET
310 320 330 340 350
KTEIMVGTVF QDTKSGKLLN SIMTAGNPDF PYQPNTQNRY NKHHLVPFGE
360 370 380 390 400
YVPLESILRP LNSVFNLPMS AFQSGEAVQP SLIAKKRAFS PAICYEIIFG
410 420 430 440 450
EQVRQNLKQD TDYLLTLSND AWFGDSIGPW QHLQMARMRA LELGKPLIRA
460 470 480 490 500
TNTGISVFVD AQGKVLAQAP QFIETTLTYK IAPAEGKTPY SVLGNMPLYA
510 520
LSLLFLLLHS MMAFIRRKMN IL
Length:522
Mass (Da):58,553
Last modified:November 1, 1995 - v1
Checksum:i8D327E5C50053C8F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA Translation: AAC21967.1
PIRiH64060
RefSeqiNP_438469.2, NC_000907.1

Genome annotation databases

EnsemblBacteriaiAAC21967; AAC21967; HI_0302
GeneIDi949425
KEGGihin:HI0302
PATRICifig|71421.8.peg.319

Similar proteinsi

Entry informationi

Entry nameiLNT_HAEIN
AccessioniPrimary (citable) accession number: P44626
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: March 28, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

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