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P44613 (MENF_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Menaquinone-specific isochorismate synthase
EC=5.4.4.2
Alternative name(s):
Isochorismate mutase
Gene names
Name:menF
Ordered Locus Names:HI_0285
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length430 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Chorismate = isochorismate.

Pathway

Cofactor biosynthesis; menaquinone biosynthesis; menaquinone-2 from chorismate: step 1/8.

Sequence similarities

Belongs to the isochorismate synthase family.

Ontologies

Keywords
   Biological processMenaquinone biosynthesis
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processmenaquinone biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionisochorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 430430Menaquinone-specific isochorismate synthase
PRO_0000154148

Sequences

Sequence LengthMass (Da)Tools
P44613 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 3BA131F8B62A1B38

FASTA43048,466
        10         20         30         40         50         60 
MYLKQNLMSY LAQAIGELKS QIHAYLQQST NELVRFQVKL DKVDLLAWLK GQSAYPQFYL 

        70         80         90        100        110        120 
HFRDEEKALA ALGAVQSFSQ LNLAQEFIEE SGFPLVGGLQ FQGTAQFVLP KMLVEQDNKG 

       130        140        150        160        170        180 
TLVSFFVKNE QSANDTLAHL KTFENLTALS ALPKQIPLHT ELRANERTWC DWVNQALVEI 

       190        200        210        220        230        240 
KSGELTKIVL ANETTFHLKQ AINAYDFLAE SEKQNQGCYH FLWAENSHSV FVGSTPERLF 

       250        260        270        280        290        300 
AREYNLLLTE ALAGTASVSE SEEETQSQAN WLLNDEKNLK ENWLVVEDIS QNLRKQVESF 

       310        320        330        340        350        360 
DVSNVELKPL RKVQHLIRKI RANLTAHYAD VNILKAIHPT AAVSGLPQQQ AKMILSEIET 

       370        380        390        400        410        420 
FDRGWYAGTL GVMSDVCSEF CVAIRSAFIE GHRIRVFAGA GIVAGSQPLE EWKEIERKAA 

       430 
GLISLFAEEK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L42023 Genomic DNA. Translation: AAC21947.1.
PIRE64059.
RefSeqNP_438452.1. NC_000907.1.

3D structure databases

ProteinModelPortalP44613.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID949812.
GenomeReviewsGene locus HI_0285 in contig L42023_GR.
KEGGhin:HI0285.
NMPDRfig|71421.1.peg.267.
PATRIC20189107. VBIHaeInf48452_0300.
TIGRHI_0285.

Phylogenomic databases

HOGENOMHBG405459.
OMAWYAGTLG.
PhylomeDBP44613.
ProtClustDBCLSK869946.

Enzyme and pathway databases

BioCycHINF71421:HI_0285-MONOMER.

Family and domain databases

InterProIPR005801. ADC_synthase.
IPR015890. Chorismate-bd_C.
IPR004561. IsoChor_synthase.
[Graphical view]
Gene3DG3DSA:3.60.120.10. TRPE_1_chor_bd. 1 hit.
KOK02552.
PANTHERPTHR11236:SF3. Isochor_synth. 1 hit.
PfamPF00425. Chorismate_bind. 1 hit.
[Graphical view]
SUPFAMSSF56322. TRPE_1_chor_bd. 1 hit.
TIGRFAMsTIGR00543. Isochor_syn. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMENF_HAEIN
AccessionPrimary (citable) accession number: P44613
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: January 25, 2012
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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