Reviewed, UniProtKB/Swiss-Prot P44589 (ARSC_HAEIN)

Names and origin

Protein names

Recommended name:
    Putative arsenate reductase
    EC=1.20.4.1

Gene names

Name:	arsC
Synonyms:	arsG
Ordered Locus Names:	HI0236

Organism

Haemophilus influenzae [Complete proteome] [HAMAP]

Taxonomic identifier

727 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	116 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Reduction of arsenate [As(V)] to arsenite [As(III)] Potential.
Catalytic activity	Arsenate + glutaredoxin = arsenite + glutaredoxin disulfide + H2O.
Sequence similarities	Belongs to the arsC family.

Ontologies

Keywords
Biological process	Arsenical resistance
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW response to arsenic Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	arsenate reductase (glutaredoxin) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 116	116	Putative arsenate reductase		PRO_0000162539

Sequences

	Sequence		Length	Mass (Da)
	P44589-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 4780A59D04C4247E	FASTA	116	13,228
	10 20 30 40 50 60 MSVIIYHNPH CSKSRETLAL LENKGIQPII ELYLQKQYSV NELQSIAKKL GIDDVRQMMR 70 80 90 100 110 TKDELYKSLN LDNLDLSQAE LFKAISEHSA LIERPIVING DKAKIGRPPE TVLEIL

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L42023 Genomic DNA. Translation: AAC21906.1.
PIR	G64056.
RefSeq	NP_438407.1.
3D structure databases
HSSP	HSSP built from PDB template 1I9D based on UniProtKB P08692.
ModBase	Search...
Genome annotation databases
GeneID	951153.
GenomeReviews	Gene locus HI0236 in contig L42023_GR.
KEGG	hin:HI0236.
TIGR	HI0236.
Phylogenomic databases
HOGENOM	P44589.
OMA	P44589. MRTKDEL.
Enzyme and pathway databases
BioCyc	HINF71421:HI_0236-MON.
BRENDA	1.20.4.1. 109.
Family and domain databases
InterPro	IPR006659. Arsenate_reductase. IPR006660. Arsenate_reductase-like. IPR012335. Thioredoxin_fold. [Graphical view]
Gene3D	G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
Pfam	PF03960. ArsC. 1 hit. [Graphical view]
TIGRFAMs	TIGR00014. arsC. 1 hit.
PROSITE	PS51353. ARSC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ARSC_HAEIN

Accession

Primary (citable) accession number: P44589

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	June 16, 2009
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)