Skip Header

Contribute Send feedback
Read comments (?) or add your own

P44569 (5NTD_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 96. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable 5'-nucleotidase
EC=3.1.3.5
Gene names
Ordered Locus Names:HI_0206
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus ›

Protein attributes

Sequence length603 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.

Cofactor

Divalent cations By similarity.

Sequence similarities

Belongs to the 5'-nucleotidase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2525 Ref.2
Chain26 – 603578Probable 5'-nucleotidase
PRO_0000000026

Regions

Region540 – 5467Substrate binding By similarity

Sites

Metal binding441Divalent metal cation 1 By similarity
Metal binding461Divalent metal cation 1 By similarity
Metal binding941Divalent metal cation 1 By similarity
Metal binding941Divalent metal cation 2 By similarity
Metal binding1261Divalent metal cation 2 By similarity
Metal binding2271Divalent metal cation 2 By similarity
Binding site4561Substrate By similarity
Site1271Transition state stabilizer By similarity
Site1301Transition state stabilizer By similarity

Secondary structure

1 .......................................................................................................... 603
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P44569 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: B641C32A5A2B6AEA

FASTA60366,245
        10         20         30         40         50         60 
MLLSKKSASF ALSAFAMLFT SVALAKEAPQ AHKAVELSIL HINDHHSYLE PHETRINLNG 

        70         80         90        100        110        120 
QQTKVDIGGF SAVNAKLNKL RKKYKNPLVL HAGDAITGTL YFTLFGGSAD AAVMNAGNFH 

       130        140        150        160        170        180 
YFTLGNHEFD AGNEGLLKLL EPLKIPVLSA NVIPDKNSIL YNKWKPYDIF TVDGEKIAII 

       190        200        210        220        230        240 
GLDTVNKTVN SSSPGKDVKF YDEIATAQIM ANALKQQGIN KIILLSHAGS EKNIEIAQKV 

       250        260        270        280        290        300 
NDIDVIVTGD SHYLYGNDEL RSLKLPVIYE YPLEFKNPNG DPVFVMEGWA YSAVVGDLGV 

       310        320        330        340        350        360 
KFSPEGIASI TRKIPHVLMS SHKLQVKNAE GKWTELTGDE RKKALDTLKS MKSISLDDHD 

       370        380        390        400        410        420 
AKTDMLISKY KSEKDRLAQE IVGVITGSAM PGGSANRIPN KAGSNPEGSI ATRFIAETMY 

       430        440        450        460        470        480 
NELKTVDLTI QNAGGVRADI LPGNVTFNDA YTFLPFGNTL YTYKMEGSLV KQVLEDAMQF 

       490        500        510        520        530        540 
ALVDGSTGAF PYGAGIRYEA NETPNAEGKR LVSVEVLNKQ TQQWEPIDDN KRYLVGTNAY 

       550        560        570        580        590        600 
VAGGKDGYKT FGKLFNDPKY EGVDTYLPDA ESFIKFMKKH PHFEAYTSSN VKFNASTDAL 


PKK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L42023 Genomic DNA. Translation: AAC21874.1.
PIRE64054.
RefSeqNP_438375.1. NC_000907.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3ZTVX-ray1.30A25-603[»]
3ZU0X-ray2.00A/B25-603[»]
ProteinModelPortalP44569.
ModBaseSearch...

Protein-protein interaction databases

STRING71421.HI0206.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC21874; AAC21874; HI_0206.
GeneID951116.
KEGGhin:HI0206.
PATRIC20188909. VBIHaeInf48452_0211.

Phylogenomic databases

eggNOGCOG0737.
KOK01081.
OMAQGDFRAL.
ProtClustDBCLSK793390.

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-8341.

Family and domain databases

Gene3D3.90.780.10. 1 hit.
InterProIPR008334. 5'-Nucleotdase_C.
IPR006146. 5'-Nucleotdase_CS.
IPR006179. 5_nucleotidase/apyrase.
IPR004843. Metallo_PEstase_dom.
IPR006420. NadN.
[Graphical view]
PANTHERPTHR11575. PTHR11575. 1 hit.
PfamPF02872. 5_nucleotid_C. 1 hit.
PF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSPR01607. APYRASEFAMLY.
SUPFAMSSF55816. 5'-Nucleotdase_C. 1 hit.
TIGRFAMsTIGR01530. nadN. 1 hit.
PROSITEPS00785. 5_NUCLEOTIDASE_1. 1 hit.
PS00786. 5_NUCLEOTIDASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry name5NTD_HAEIN
AccessionPrimary (citable) accession number: P44569
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 1, 2013
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents