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P44560 (TATC_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Sec-independent protein translocase protein TatC
Gene names
Name:tatC
Ordered Locus Names:HI_0188
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length256 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides By similarity. HAMAP-Rule MF_00902

Subunit structure

The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon By similarity.

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_00902.

Sequence similarities

Belongs to the TatC family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 256256Sec-independent protein translocase protein TatC HAMAP-Rule MF_00902
PRO_0000098086

Regions

Transmembrane25 – 4521Helical; Potential
Transmembrane77 – 9721Helical; Potential
Transmembrane117 – 13721Helical; Potential
Transmembrane158 – 17821Helical; Potential
Transmembrane195 – 21521Helical; Potential
Transmembrane217 – 23721Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P44560 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: F69971A264928DCC

FASTA25628,734
        10         20         30         40         50         60 
MSNVDESQPL ITHLVELRNR LLRCVICVVL VFVALVYFSN DIYHFVAAPL TAVMPKGATM 

        70         80         90        100        110        120 
IATNIQTPFF TPIKLTAIVA IFISVPYLLY QIWAFIAPAL YQHEKRMIYP LLFSSTILFY 

       130        140        150        160        170        180 
CGVAFAYYIV FPLVFSFFTQ TAPEGVTIAT DISSYLDFAL ALFLAFGVCF EVPIAIILLC 

       190        200        210        220        230        240 
WTGITTVKAL SEKRPYIIVA AFFIGMLLTP PDVFSQTLLA IPMCLLFELG LLVARFYQPK 

       250 
DDESAVKNND ESEKTQ 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L42023 Genomic DNA. Translation: AAC21857.1.
PIRC64145.
RefSeqNP_438357.1. NC_000907.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING71421.HI0188.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC21857; AAC21857; HI_0188.
GeneID951098.
KEGGhin:HI0188.
PATRIC20188873. VBIHaeInf48452_0193.

Phylogenomic databases

eggNOGCOG0805.
KOK03118.
OMAVILHQIW.
OrthoDBEOG60SCQS.
PhylomeDBP44560.

Family and domain databases

HAMAPMF_00902. TatC.
InterProIPR019820. Sec-indep_translocase_CS.
IPR002033. TatC.
[Graphical view]
PfamPF00902. TatC. 1 hit.
[Graphical view]
PRINTSPR01840. TATCFAMILY.
TIGRFAMsTIGR00945. tatC. 1 hit.
PROSITEPS01218. TATC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTATC_HAEIN
AccessionPrimary (citable) accession number: P44560
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: July 9, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names