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P44560

- TATC_HAEIN

UniProt

P44560 - TATC_HAEIN

Protein

Sec-independent protein translocase protein TatC

Gene

tatC

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 95 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.UniRule annotation

    GO - Molecular functioni

    1. protein transmembrane transporter activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. protein transport by the Tat complex Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Protein transport, Translocation, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Sec-independent protein translocase protein TatCUniRule annotation
    Gene namesi
    Name:tatCUniRule annotation
    Ordered Locus Names:HI_0188
    OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
    Taxonomic identifieri71421 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000000579: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of plasma membrane Source: UniProtKB-HAMAP
    2. TAT protein transport complex Source: UniProtKB-HAMAP

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 256256Sec-independent protein translocase protein TatCPRO_0000098086Add
    BLAST

    Interactioni

    Subunit structurei

    The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.UniRule annotation

    Protein-protein interaction databases

    STRINGi71421.HI0188.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei25 – 4521HelicalUniRule annotationAdd
    BLAST
    Transmembranei77 – 9721HelicalUniRule annotationAdd
    BLAST
    Transmembranei117 – 13721HelicalUniRule annotationAdd
    BLAST
    Transmembranei158 – 17821HelicalUniRule annotationAdd
    BLAST
    Transmembranei195 – 21521HelicalUniRule annotationAdd
    BLAST
    Transmembranei217 – 23721HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TatC family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0805.
    KOiK03118.
    OMAiVILHQIW.
    OrthoDBiEOG60SCQS.
    PhylomeDBiP44560.

    Family and domain databases

    HAMAPiMF_00902. TatC.
    InterProiIPR019820. Sec-indep_translocase_CS.
    IPR002033. TatC.
    [Graphical view]
    PfamiPF00902. TatC. 1 hit.
    [Graphical view]
    PRINTSiPR01840. TATCFAMILY.
    TIGRFAMsiTIGR00945. tatC. 1 hit.
    PROSITEiPS01218. TATC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P44560-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSNVDESQPL ITHLVELRNR LLRCVICVVL VFVALVYFSN DIYHFVAAPL    50
    TAVMPKGATM IATNIQTPFF TPIKLTAIVA IFISVPYLLY QIWAFIAPAL 100
    YQHEKRMIYP LLFSSTILFY CGVAFAYYIV FPLVFSFFTQ TAPEGVTIAT 150
    DISSYLDFAL ALFLAFGVCF EVPIAIILLC WTGITTVKAL SEKRPYIIVA 200
    AFFIGMLLTP PDVFSQTLLA IPMCLLFELG LLVARFYQPK DDESAVKNND 250
    ESEKTQ 256
    Length:256
    Mass (Da):28,734
    Last modified:November 1, 1995 - v1
    Checksum:iF69971A264928DCC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC21857.1.
    PIRiC64145.
    RefSeqiNP_438357.1. NC_000907.1.

    Genome annotation databases

    EnsemblBacteriaiAAC21857; AAC21857; HI_0188.
    GeneIDi951098.
    KEGGihin:HI0188.
    PATRICi20188873. VBIHaeInf48452_0193.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC21857.1 .
    PIRi C64145.
    RefSeqi NP_438357.1. NC_000907.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 71421.HI0188.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC21857 ; AAC21857 ; HI_0188 .
    GeneIDi 951098.
    KEGGi hin:HI0188.
    PATRICi 20188873. VBIHaeInf48452_0193.

    Phylogenomic databases

    eggNOGi COG0805.
    KOi K03118.
    OMAi VILHQIW.
    OrthoDBi EOG60SCQS.
    PhylomeDBi P44560.

    Family and domain databases

    HAMAPi MF_00902. TatC.
    InterProi IPR019820. Sec-indep_translocase_CS.
    IPR002033. TatC.
    [Graphical view ]
    Pfami PF00902. TatC. 1 hit.
    [Graphical view ]
    PRINTSi PR01840. TATCFAMILY.
    TIGRFAMsi TIGR00945. tatC. 1 hit.
    PROSITEi PS01218. TATC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

    Entry informationi

    Entry nameiTATC_HAEIN
    AccessioniPrimary (citable) accession number: P44560
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 95 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Haemophilus influenzae
      Haemophilus influenzae (strain Rd): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3