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P44560

- TATC_HAEIN

UniProt

P44560 - TATC_HAEIN

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Protein

Sec-independent protein translocase protein TatC

Gene
tatC, HI_0188
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides By similarity.UniRule annotation

GO - Molecular functioni

  1. protein transmembrane transporter activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. protein transport by the Tat complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Sec-independent protein translocase protein TatC
Gene namesi
Name:tatC
Ordered Locus Names:HI_0188
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei25 – 4521Helical; Reviewed predictionAdd
BLAST
Transmembranei77 – 9721Helical; Reviewed predictionAdd
BLAST
Transmembranei117 – 13721Helical; Reviewed predictionAdd
BLAST
Transmembranei158 – 17821Helical; Reviewed predictionAdd
BLAST
Transmembranei195 – 21521Helical; Reviewed predictionAdd
BLAST
Transmembranei217 – 23721Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of plasma membrane Source: UniProtKB-HAMAP
  2. TAT protein transport complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 256256Sec-independent protein translocase protein TatCUniRule annotationPRO_0000098086Add
BLAST

Interactioni

Subunit structurei

The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon By similarity.

Protein-protein interaction databases

STRINGi71421.HI0188.

Family & Domainsi

Sequence similaritiesi

Belongs to the TatC family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0805.
KOiK03118.
OMAiVILHQIW.
OrthoDBiEOG60SCQS.
PhylomeDBiP44560.

Family and domain databases

HAMAPiMF_00902. TatC.
InterProiIPR019820. Sec-indep_translocase_CS.
IPR002033. TatC.
[Graphical view]
PfamiPF00902. TatC. 1 hit.
[Graphical view]
PRINTSiPR01840. TATCFAMILY.
TIGRFAMsiTIGR00945. tatC. 1 hit.
PROSITEiPS01218. TATC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P44560-1 [UniParc]FASTAAdd to Basket

« Hide

MSNVDESQPL ITHLVELRNR LLRCVICVVL VFVALVYFSN DIYHFVAAPL    50
TAVMPKGATM IATNIQTPFF TPIKLTAIVA IFISVPYLLY QIWAFIAPAL 100
YQHEKRMIYP LLFSSTILFY CGVAFAYYIV FPLVFSFFTQ TAPEGVTIAT 150
DISSYLDFAL ALFLAFGVCF EVPIAIILLC WTGITTVKAL SEKRPYIIVA 200
AFFIGMLLTP PDVFSQTLLA IPMCLLFELG LLVARFYQPK DDESAVKNND 250
ESEKTQ 256
Length:256
Mass (Da):28,734
Last modified:November 1, 1995 - v1
Checksum:iF69971A264928DCC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC21857.1.
PIRiC64145.
RefSeqiNP_438357.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC21857; AAC21857; HI_0188.
GeneIDi951098.
KEGGihin:HI0188.
PATRICi20188873. VBIHaeInf48452_0193.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC21857.1 .
PIRi C64145.
RefSeqi NP_438357.1. NC_000907.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 71421.HI0188.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC21857 ; AAC21857 ; HI_0188 .
GeneIDi 951098.
KEGGi hin:HI0188.
PATRICi 20188873. VBIHaeInf48452_0193.

Phylogenomic databases

eggNOGi COG0805.
KOi K03118.
OMAi VILHQIW.
OrthoDBi EOG60SCQS.
PhylomeDBi P44560.

Family and domain databases

HAMAPi MF_00902. TatC.
InterProi IPR019820. Sec-indep_translocase_CS.
IPR002033. TatC.
[Graphical view ]
Pfami PF00902. TatC. 1 hit.
[Graphical view ]
PRINTSi PR01840. TATCFAMILY.
TIGRFAMsi TIGR00945. tatC. 1 hit.
PROSITEi PS01218. TATC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiTATC_HAEIN
AccessioniPrimary (citable) accession number: P44560
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: July 9, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi