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P44554 (NAGK_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-acetyl-D-glucosamine kinase

EC=2.7.1.59
Alternative name(s):
GlcNAc kinase
Gene names
Name:nagK
Ordered Locus Names:HI_0182
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length304 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P By similarity. HAMAP-Rule MF_01271

Catalytic activity

ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate. HAMAP-Rule MF_01271

Pathway

Cell wall biogenesis; peptidoglycan recycling. HAMAP-Rule MF_01271

Sequence similarities

Belongs to the ROK (NagC/XylR) family. NagK subfamily.

Sequence caution

The sequence AAC21851.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 304304N-acetyl-D-glucosamine kinase HAMAP-Rule MF_01271
PRO_0000095719

Regions

Nucleotide binding4 – 118ATP Potential
Nucleotide binding133 – 1408ATP Potential

Sites

Metal binding1571Zinc By similarity
Metal binding1781Zinc By similarity
Metal binding1801Zinc By similarity
Metal binding1851Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
P44554 [UniParc].

Last modified November 28, 2006. Version 2.
Checksum: 97E174C5EF48CB7F

FASTA30433,107
        10         20         30         40         50         60 
MYYGLDIGGT KIELAVFNEK LEKLYSERVP TPKTDYEEWL NTIVDLVNRA DEKFGEVGTV 

        70         80         90        100        110        120 
GLGVPGFVNQ QTGLAEIANI RVADNKPILC DLSTRLGREV RAENDANCFA LSEAWDTENQ 

       130        140        150        160        170        180 
QYSTVLGLIL GTGFGGGFVL NGKVHSGQVG MAGELGHLQL NYHALKLLGW DNAPIYQCGC 

       190        200        210        220        230        240 
GNKACLDNYL SGRGFEMLYQ DLKGETLSAR KIINLFYQSN ESAVDFVNLF VELAAISIGN 

       250        260        270        280        290        300 
IITAFDPHMI VLGGGLSNFD YLYEALPKAL PPHLMRKAKV PPIKKAKHGD SGGVRGAAAL 


FLTK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L42023 Genomic DNA. Translation: AAC21851.1. Different initiation.
PIRH64144.
RefSeqNP_438350.2. NC_000907.1.

3D structure databases

ProteinModelPortalP44554.
SMRP44554. Positions 1-303.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING71421.HI0182.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC21851; AAC21851; HI_0182.
GeneID951092.
KEGGhin:HI0182.
PATRIC20188859. VBIHaeInf48452_0186.

Phylogenomic databases

eggNOGCOG1940.
KOK00884.
OMAPEIVAQW.
OrthoDBEOG61P6P0.
PhylomeDBP44554.

Enzyme and pathway databases

UniPathwayUPA00544.

Family and domain databases

HAMAPMF_01271. GlcNAc_kinase.
InterProIPR023505. N-acetyl-D-glucosamine_kinase.
IPR000600. ROK.
[Graphical view]
PfamPF00480. ROK. 1 hit.
[Graphical view]
PROSITEPS01125. ROK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNAGK_HAEIN
AccessionPrimary (citable) accession number: P44554
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 28, 2006
Last modified: July 9, 2014
This is version 85 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names