Reviewed, UniProtKB/Swiss-Prot P44537 (NAGA_HAEIN)

Names and origin

Protein names

Recommended name:
    N-acetylglucosamine-6-phosphate deacetylase
    EC=3.5.1.25
Alternative name(s):
    GlcNAc 6-P deacetylase

Gene names

Name:	nagA
Ordered Locus Names:	HI0140

Organism

Haemophilus influenzae [Complete proteome] [HAMAP]

Taxonomic identifier

727 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	381 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate.
Sequence similarities	Belongs to the nagA family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	N-acetylglucosamine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	N-acetylglucosamine-6-phosphate deacetylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 381	381	N-acetylglucosamine-6-phosphate deacetylase		PRO_0000170917

Sequences

	Sequence		Length	Mass (Da)
	P44537-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: A502DF70BC03965A	FASTA	381	41,593
	10 20 30 40 50 60 MKYALINCVI YTKYDVLRDF AVIINGEIIE AVIPQAELET GIKTIDLQGN NLTAGFIDLQ 70 80 90 100 110 120 LNGCGGVMFN DQTSVETLEI MQETNLKSGC TSFLPTFITA PDENIKSAVK IMREYLNKHK 130 140 150 160 170 180 NQALGLHIEG PYLSIEKKGV HRPEYIREIT PEMKDFLCEN GDVITKMTIA AENPTINYTP 190 200 210 220 230 240 DFVKAGIIVS VGHSNATYEV AKAAFHKGAT FATHLHNAMS PISSGREMGV VGAVLDSDVY 250 260 270 280 290 300 TGIIVDGVHI NYGNVRIDKK IKGDKLCIVT DSIAAAGAPP ELESFTFVGK TIYIKEGRCY 310 320 330 340 350 360 DANDTIAGAS ITMMESIKNA VEYVEIPLAE AIRMSNLYPA RAIGIDDRLG SVEKGKIANL 370 380 AVFTPNYQVI GTVVNGKWKE N

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC21812.1.
PIR	E64050.
RefSeq	NP_438309.1.
3D structure databases
SMR	P44537. Positions 3-379.
ModBase	Search...
Genome annotation databases
GeneID	951049.
GenomeReviews	Gene locus HI0140 in contig L42023_GR.
KEGG	hin:HI0140.
NMPDR	fig|71421.1.peg.131.
TIGR	HI0140.
Phylogenomic databases
HOGENOM	HBG464950.
OMA	TSSDEDM.
Enzyme and pathway databases
BioCyc	HINF71421:HI_0140-MONOMER.
BRENDA	3.5.1.25. 109.
Family and domain databases
InterPro	IPR006680. Amidohydro_1. IPR003764. GlcNAc_6-P_deAcase. IPR011059. Metal-dep_hydrolase_composite. [Graphical view]
Pfam	PF01979. Amidohydro_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR00221. nagA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

NAGA_HAEIN

Accession

Primary (citable) accession number: P44537

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	February 9, 2010
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)